Gluten/Dairy Digest Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Gluten/Dairy Digest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gluten/Dairy Digest is a dietary supplement by Pure Encapsulations with 3 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Gluten/Dairy Digest by Pure Encapsulations
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Gluten/Dairy Digest has three active ingredients. Lactase is an enzyme that breaks down lactose (milk sugar), the carbohydrate in dairy that causes bloating and discomfort in people who can't digest it well.
Protease is another enzyme that helps break down proteins in your food. Tolerase G is a blend ingredient — the product uses component ingredients within it, though their individual details aren't on file for us here.
The capsule also contains cellulose and water as inactive ingredients (fillers and capsule material).
Does it work?
Strong evidence
Lactase is effective for lactose intolerance — the main claim of this product. For other uses like prematurity or colic, the evidence isn't strong enough to rate.
We don't have effectiveness data on file for protease or the Tolerase G blend in this context, so we can't tell you how well they work for the product's intended purpose.
How safe is it?
Well-documented data
Lactase is generally well tolerated when you take it as directed. Protease is also generally well tolerated for most adults, though it may cause digestive upset or allergic reactions in some people.
A rare allergic reaction to lactase itself has been reported in one worker exposed to powdered lactase — itching and nasal/eye symptoms confirmed by allergy testing. Protease can trigger occupational airway allergies in rare cases, but that's mainly from workplace inhalation exposure, not from swallowing it in a supplement.
During pregnancy, lactase is likely safe, but talk with your doctor before taking it regularly. Protease safety hasn't been established in pregnancy, so it's best avoided unless your doctor prescribes it.
During breastfeeding, lactase is likely safe, but there's little safety data on protease, so check with your doctor or pharmacist first. We don't have pregnancy or breastfeeding safety data on file for Tolerase G.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. This doesn't guarantee none exist — check your exact medications with the search tool on this page before you start.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product is straightforward for people with lactose intolerance who want enzyme support. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before starting — especially about the protease component.
Check your medications with the tool on this page, and run any questions about how it fits into your routine by your own healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gluten/Dairy Digest, straight from the product label.
| Brand | Pure Encapsulations |
|---|---|
| Barcode (UPC) | 766298023649 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2023 |
| DSLD ID | 293967 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gluten/Dairy Digest by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactase | 0 NP | -- |
| Tolerase G | 0 NP | -- |
| Protease | 0 NP | -- |
| BioCore Dairy | 105 mg | -- |
Other ingredients: Cellulose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Recommendations: as a dietary supplement, take 1 capsule as needed, with a meal, or as directed by a health care professional.
Precautions
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
Tolerase G is not intended to replace a gluten-free diet. Tolerase G is not intended to treat or prevent celiac disease.
General Statements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements.
Seals/Symbols
GFCO.org (Gluten-Free Certification Organization)
Formulation
Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org
Supports gluten and dairy digestion
Gluten-free, non-GMO & hypoallergenic
Gluten-free, non-GMO & hypoallergenic
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
BioCore is a trademark of National Enzyme Company. Tolerase G is a trademark of DSM.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gluten/Dairy Digest by Pure Encapsulations label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gluten/Dairy Digest by Pure Encapsulations
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.
Gluten/Dairy Digest by Pure Encapsulations Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Gluten/Dairy Digest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Gluten/Dairy Digest, from the product label.
Pure Encapsulations
See all Pure Encapsulations products- Name
- Pure Encapsulations
- Street Address
- 490 Boston Post Road
- City
- Sudbury
- State
- MA
- Phone Number
- 1-800-753-2277
- Web Address
- www.PureEncapsulations.com
Gluten/Dairy Digest by Pure Encapsulations: Common Questions
Does Gluten/Dairy Digest by Pure Encapsulations interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is lactase safe if I'm pregnant or breastfeeding?
Does lactase actually work for lactose intolerance?
Can I be allergic to the ingredients in this product?
What does the protease do in this product?
What is Tolerase G?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gluten/Dairy Digest is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gluten/Dairy Digest’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Gluten/Dairy Digest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC