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Dietary supplement

Glycine Powder Ingredients & Drug Interactions

by Carlson

Glycine Powder label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glycine Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glycine Powder is a dietary supplement by Carlson with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glycine Powder by Carlson

Ask about any prescription or over-the-counter medication and we check it for interactions with Glycine Powder by Carlson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glycine Powder by Carlson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Carlson Glycine Powder contains one active ingredient: glycine, an amino acid your body uses in protein synthesis and other processes. It's a straightforward, single-ingredient supplement with no inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Glycine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: energy, sleep, and collagen production.
  • We looked for evidence on: Insomnia, Cognitive function, Physical performance, Wound healing, Aging, Sleep quality — and 2 related terms.
  • The closest evidence on file: Glycine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function (Natural Medicines).
  • Also on file: Glycine is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Wound healing, Physical performance, Aging.

The evidence for glycine is mixed. It's rated possibly effective for schizophrenia, meaning some clinical support exists — though that support includes the finding that adding it to clozapine may actually worsen symptoms.

For other uses listed in our data — 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, ADHD, benign prostatic hyperplasia (enlarged prostate), and cystic fibrosis — there isn't enough reliable evidence to rate how well it works.

The evidence, ingredient by ingredient Glycine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, but long-term safety data are limited. Mild side effects have been reported rarely, including sedation, soft stools, nausea, vomiting, upper stomach discomfort, and dry mouth — these resolve quickly if you stop taking it.

Other symptoms like irritability, insomnia, fatigue, memory problems, headache, and sensory changes have been reported, but it's unclear whether glycine caused them. There isn't enough reliable safety data on glycine in pregnancy or while breastfeeding, so it's best avoided unless your doctor approves.

Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Glycine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glycine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take clozapine (Clozaril), an antipsychotic medication, check with your doctor or pharmacist before adding this product — glycine may make it less effective and could worsen schizophrenia symptoms.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Glycine powder may be worth considering if you're interested in its uses, but the evidence is limited for most conditions. If you take clozapine for schizophrenia, you'll need to clear this with your doctor first — the interaction could worsen your symptoms.

Check your exact medications with the search tool on this page, and talk it over with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glycine Powder, straight from the product label.

Brand Carlson
Barcode (UPC) 088395683602
Net contents 17.6 Ounce(s); 1.1 lb(s); 500 Gram(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 309283
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glycine Powder by Carlson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
250
UPC/BARCODE
088395683602
IngredientAmount% DV
Glycine2 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Free-form amino acid

Glycine helps maintain optimal energy levels and a healthy metabolism, promotes relaxation and a healthy sleep pattern, and plays an important role in collagen production. Glycine in powder form promotes superior absorption.

FDA Statement of Identity

Dietary Supplement

Formulation

Energy support Healthy sleep Collagen production

Gluten-free No artificial preservatives

Potency & quality guaranteed An FDA Regulated Facility

This product may vary in appearance and consistency.

IGEN Non-GMO tested

Suggested/Recommended/Usage/Directions

Directions: Adults: Take 1/2 teaspoonful (one level scoopful) daily mixed into food or liquid.

Storage

Keep bottle tightly closed. Store away from heat and moisture.

This product is sold by weight not volume.

Precautions

Warning: Do not take if you are pregnant or lactating or are sensitive to glycine.

Brand IP Statement(s)

Carlson Providing the highest quality nutritional supplements since 1965

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Reduced Plastic Impact Impact Collective

Seals/Symbols

IGEN Non-GMO tested

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glycine Powder by Carlson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glycine Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glycine Powder by Carlson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container250 Amounts shown are per serving.

Glycine

Interacts with
1 drug
2 Gram(s) per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions
Interaction report

Glycine Powder by Carlson Drug Interactions

Want to check YOUR meds against Glycine Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Glycine 1

Individual Drug Interactions

The ingredients in Glycine Powder interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Glycine Powder interact with drugs. Each result below shows which ingredient is responsible. Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glycine Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glycine Powder, from the product label.

Carlson

See all Carlson products
Name
Carlson Division of J.R. Carlson Laboratories, Inc.
City
Arlington Heights
State
IL
ZipCode
60004
Phone Number
888-234-5656
Web Address
carlsonlabs.com
Pharmacist Counseling Corner

Glycine Powder by Carlson: Common Questions

Does Glycine Powder by Carlson interact with any medications?
Yes. Based on its ingredients, Glycine Powder has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glycine Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glycine the same as the amino acid in protein?
Yes, glycine is a naturally occurring amino acid that your body uses to build and repair proteins and for other important functions. This supplement provides it in concentrated form as a powder.
Can glycine help with ADHD?
There isn't enough reliable evidence in our data to rate how well glycine works for ADHD. If you're interested in trying it, talk with your doctor about whether it makes sense for your situation.
What side effects might I experience?
Side effects are rare, but they can include mild sedation, soft stools, nausea, vomiting, or stomach discomfort. These typically go away quickly if you stop taking it. A few people have reported irritability, insomnia, or headache, though it's unclear if glycine caused them.
Is it safe to use while pregnant or breastfeeding?
There isn't enough reliable safety data to know either way. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before using this product.
How long has glycine been studied?
Long-term safety data for glycine are limited, so we don't have as much information about its effects over months or years as we'd like. Your doctor or pharmacist can discuss what that means for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glycine Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glycine Powder label
Go deeper

The Full Monographs Behind Glycine Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph →
Sources

Sources & How We Checked

Glycine Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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