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Dietary supplement

Grass Fed Beef Liver 500 mg Ingredients & Drug Interactions

by Optimal Carnivore

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Grass Fed Beef Liver 500 mg is a dietary supplement by Optimal Carnivore with 1 active ingredient. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are New Zealand Bovine Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Grass Fed Beef Liver 500 mg by Optimal Carnivore

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: New Zealand Bovine Liver at 500 mg per capsule. Beef liver is nutrient-dense and delivers a range of vitamins and minerals naturally present in the tissue.

The capsule itself is made from gelatin, an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for beef liver extract in chronic fatigue syndrome (CFS) rates as possibly ineffective — meaning studies do not support its use for that condition. For hepatitis C, there isn't enough reliable evidence to rate whether it works.

We don't hold data on effectiveness for other uses.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beef liver products are generally low risk for healthy adults eating food amounts, but this supplement can deliver high levels of vitamin A and iron — both of which can cause problems at high doses. There's also a source-quality concern: liver extract comes from raw animal livers collected at slaughterhouses, and there's theoretical risk of contamination from sick animals or, in countries where BSE (mad cow disease) has been reported, from diseased tissue.

No cases of BSE transfer to humans from liver extract have been reported, but the safety data is limited. Because of the high vitamin A content, pregnant women should avoid this product unless a doctor advises otherwise.

A thorough safety evaluation hasn't been done, so check with your doctor before using.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking if you use warfarin (Coumadin) — a blood thinner — or iron supplements or iron-containing medications. Both interactions are minor but worth confirming with your exact drugs using the tool below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is a single-ingredient beef liver supplement, primarily of interest to people following a carnivore diet or seeking whole-food nutrition. If you take warfarin, iron supplements, or have an iron-overload condition, check your exact medications first.

Pregnant women and anyone with liver disease or BSE concerns should talk to their doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Grass Fed Beef Liver 500 mg, straight from the product label.

Brand Optimal Carnivore
Barcode (UPC) X002INKUVH
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 323269
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Grass Fed Beef Liver 500 mg by Optimal Carnivore, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
X002INKUVH
IngredientAmount% DV
New Zealand Bovine Liver3000 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Helping you thrive with the most nutrient dense foods on the planet We believe that everyone deserves access to the most nutrient-dense food on the planet in a convenient, easy to take form. We only source from 100% grass-fed animals in New Zealand-one of the cleanest purest environments on earth. The cattle are reared as nature intended, without the use of growth-promoting hormones, free to roam grass pastures. We gently freeze-dry the organs to preserve all the vitamins, minerals, proteins and enzymes.

Nothing but nutrients Hormone-free & Non-GMO. 100% additive-free. No stearates, lubricants, binders, fillers or flow agents.

New Zealand

Formula

Six capsules provide the equivalent of one ounce of fresh, raw whole organs.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 6 capsules daily or as directed by a healthcare professional

Seals/Symbols

GMP Quality Good Manufacturing Practice Certification Made in USA

See for yourself

Grass Fed Beef Liver 500 mg by Optimal Carnivore label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Grass Fed Beef Liver 500 mg by Optimal Carnivore

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

New Zealand Bovine Liver

Interacts with
3 drugs
3000 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

New Zealand Bovine Liver monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Grass Fed Beef Liver 500 mg by Optimal Carnivore Drug Interactions

Want to check YOUR meds against Grass Fed Beef Liver 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Grass Fed Beef Liver 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

New Zealand Bovine Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Grass Fed Beef Liver 500 mg, from the product label.

Optimal Carnivore

See all Optimal Carnivore products
Name
Optimal Carnivore, LLC
Street Address
13359 N Hwy 183, Ste 406.
City
Austin
State
TX
ZipCode
78750
Web Address
www.optimalcarnivore.com
Pharmacist Counseling Corner

Grass Fed Beef Liver 500 mg by Optimal Carnivore: Common Questions

Does Grass Fed Beef Liver 500 mg by Optimal Carnivore interact with any medications?
Yes. Based on its ingredients, Grass Fed Beef Liver 500 mg has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Grass Fed Beef Liver 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy?
No — beef liver is very high in vitamin A, which can harm a developing baby. Avoid it unless your doctor specifically advises you to use it.
Can this help with chronic fatigue?
The evidence suggests it's probably not effective for chronic fatigue syndrome. If you're considering it for that reason, talk with your doctor about better-studied options.
What's the concern about BSE (mad cow disease)?
Liver extract comes from raw animal livers from slaughterhouses. In countries where BSE has been reported — including Great Britain, France, and several others — there's theoretical risk of contaminated tissue in the product. No human BSE cases from liver extract have been reported, but if you're concerned, check the country of origin before buying.
Will this raise my iron levels too high?
Beef liver contains natural heme iron. If you're already taking iron supplements or iron medications, combining them could push your total intake higher and cause stomach upset or iron buildup — especially over time or at high doses. If you have hemochromatosis or another iron-storage condition, this is a bigger concern.
What's in one capsule besides the liver?
Just gelatin — the capsule material. There are no other active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Grass Fed Beef Liver 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Grass Fed Beef Liver 500 mg label
Go deeper

The Full Monographs Behind Grass Fed Beef Liver 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Grass Fed Beef Liver 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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