Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Grassfed Beef Heart Ingredients & Drug Interactions

by Ancestral Supplements

Grassfed Beef Heart label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Grassfed Beef Heart against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Grassfed Beef Heart is a dietary supplement by Ancestral Supplements with 2 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Grassfed Beef Heart by Ancestral Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Grassfed Beef Heart by Ancestral Supplements — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Grassfed Beef Heart by Ancestral Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: beef liver extract and beef heart. Liver has been used traditionally to support energy and whole-body function.

Heart is included as an organ-support supplement, though the evidence for its specific effects isn't established in the data we hold. The capsules also contain gelatin as an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

For chronic fatigue syndrome, liver extract is rated possibly ineffective — meaning the evidence doesn't suggest it works for that condition. For hepatitis C, the evidence is too thin to rate either way.

We don't hold effectiveness data for the heart ingredient.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Liver products carry some important cautions. They naturally contain high levels of vitamin A and iron, which is fine in food amounts but can become a concern at supplement doses.

There's also a source-quality issue: liver extract comes from raw animal liver at slaughterhouses, and there's a small theoretical risk of contamination with diseased tissue or, in rare cases, BSE (mad cow disease) if sourced from affected countries, though no human cases from contaminated liver extract have ever been reported. Pregnancy is a particular concern — the high vitamin A content may harm a developing baby, so you should avoid this product in pregnancy unless your doctor advises otherwise.

Safety hasn't been thoroughly studied overall, so check with your doctor before starting, especially if you have an iron-storage condition or are pregnant or nursing.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your pharmacist or use the tool below if you take warfarin (a blood thinner) or any iron supplements or iron-containing medications. We couldn't check the heart ingredient for interactions, so run your full medication list through the checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is a niche product best suited to people interested in nose-to-tail nutrition who don't take warfarin or iron supplements. If you're on either of those, check with your pharmacist first.

Pregnant or nursing mothers should skip it unless cleared by their doctor. Talk to us before you start if you have any iron-overload condition or take regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Grassfed Beef Heart, straight from the product label.

Brand Ancestral Supplements
Barcode (UPC) 675757264243
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 275553
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Grassfed Beef Heart by Ancestral Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
675757264243
IngredientAmount% DV
Liver300 mg--
Heart3000 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

For most of human history, we consumed the whole animal (nose-to-tail), with deep respect and profound purpose. For instance, Native Americans and early ancestral healers believed and supported the health of the corresponding organ of the individual- also known as "like supports like." The traditional way of treating a person with a weak heart was to feed the person the heart of a healthy animal. Since we've abandoned these ways, the modern world has left us malnourished with an epidemic of declining health. The solution is to find ways to recreate our ancestral environment (sleep, nourishment, movement, sunshine, etc). It's time we honor our ancestors by putting back in what the modern world has left out (to return our people back to strength, health and happiness). We walk our talk and we offer a one-of-a-kind "guided" experience. Learn more at www.ancestralsupplements.com

Brian Johnson "Liver King"

One small batch at a time

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Pasture-raised in New Zealand & Australia Grass-fed & grass-finished

Hormone, pesticide & GMO free Absolutely no fillers (or) flow agents

Formula

180 capsules 550 mg ea

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 6 capsules daily or as directed by a healthcare professional

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Grassfed Beef Heart by Ancestral Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Grassfed Beef Heart label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Grassfed Beef Heart by Ancestral Supplements

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Liver

Interacts with
3 drugs
300 mg per serving Form: Bovine

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Liver monograph & interactions

Heart

3000 mg per serving Form: Bovine

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Grassfed Beef Heart by Ancestral Supplements Drug Interactions

Want to check YOUR meds against Grassfed Beef Heart?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Liver 3

Individual Drug Interactions

The ingredients in Grassfed Beef Heart interact with 3 drugs. Click any drug to see the details.

1 of the 2 ingredients in Grassfed Beef Heart interact with drugs. Each result below shows which ingredient is responsible. Liver

Each ingredient & the kinds of drugs it affects

For each ingredient in Grassfed Beef Heart with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
Liver full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Grassfed Beef Heart, from the product label.

Ancestral Supplements

See all Ancestral Supplements products
Name
Ancestral Supplements, LLC
City
Willis
State
TX
ZipCode
77318
Web Address
www.ancestralsupplements.com
Pharmacist Counseling Corner

Grassfed Beef Heart by Ancestral Supplements: Common Questions

Does Grassfed Beef Heart by Ancestral Supplements interact with any medications?
Yes. Based on its ingredients, Grassfed Beef Heart has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Grassfed Beef Heart contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
Liver extract contains very high vitamin A, which can harm a developing baby, so you should avoid this product in pregnancy unless your doctor tells you it's okay. Safety during breastfeeding hasn't been well studied either, so talk with your doctor or pharmacist before using it while nursing.
Can I take this if I have an iron-storage condition like hemochromatosis?
This product contains heme iron from beef liver, so there's a risk of iron overload or stomach problems if you have hemochromatosis or another condition where your body stores too much iron. Check with your doctor before starting.
What's the concern about BSE or contamination?
Liver extract comes from raw animal liver at slaughterhouses, and there's a small theoretical risk of contamination with diseased tissue or BSE if sourced from certain countries. No human cases from contaminated liver extract have ever been reported, but the product's origin matters — ask the brand where their beef comes from.
How well does this work for chronic fatigue?
The evidence doesn't support liver extract for chronic fatigue syndrome — it's rated possibly ineffective for that condition. If that's why you're considering it, this may not be the right choice.
What does the heart ingredient do?
Heart is included as an organ-support supplement, but we don't have effectiveness data on file for it, so we can't tell you what it's designed to do beyond that traditional use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Grassfed Beef Heart label
Go deeper

The Full Monographs Behind Grassfed Beef Heart’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Liver Extract

Interacts with 3 drugs

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once used to treat certain anemias before pu...

Read the full Liver Extract monograph →
Sources

Sources & How We Checked

Grassfed Beef Heart's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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