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Dietary supplement

Grassfed Beef Liver Ingredients & Drug Interactions

by Ancestral Supplements

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Grassfed Beef Liver is a dietary supplement by Ancestral Supplements with 1 active ingredient. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Bovine Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Grassfed Beef Liver by Ancestral Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bovine liver (grassfed beef liver). The capsules also contain gelatin as an inactive ingredient.

Beef liver is nutrient-dense and has been used traditionally as a nutritional supplement. The product is designed to deliver whole-food liver in capsule form.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on beef liver for chronic fatigue syndrome (CFS) is not in our favor — it's rated possibly ineffective. For hepatitis C, there isn't enough reliable evidence to know one way or the other.

We don't hold effectiveness data for other uses you may have in mind, so ask us if you're considering this for something specific.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported in the data we hold, but a full safety evaluation hasn't been done. The bigger concerns are practical: liver products deliver very high amounts of vitamin A and iron, which matters if you're taking other supplements or have conditions affecting how your body handles those nutrients.

There's also a sourcing question — liver extract comes from raw animal liver at slaughterhouses, raising potential concerns about contamination from sick animals or, in rare cases, mad cow disease (BSE) if the cattle came from affected countries. No human cases of BSE from liver extract have been reported, but the risk exists until more is known.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take warfarin (Coumadin) — vitamin K in liver extract can reduce its blood-thinning effect. Also flag any iron supplements or iron-containing drugs, since adding liver extract increases total iron intake.

Use the search tool on this page to verify your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This product is generally low-risk for healthy adults eating normal food amounts of liver, but it concentrates vitamin A and iron significantly. If you take warfarin, iron supplements, or have iron-overload issues, check with your pharmacist first.

Pregnant people should avoid it due to high vitamin A content unless a doctor advises otherwise. Ask us about the source country to confirm BSE risk is minimal.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Grassfed Beef Liver, straight from the product label.

Brand Ancestral Supplements
Barcode (UPC) 789185534783
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 309431
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Grassfed Beef Liver by Ancestral Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
789185534783
IngredientAmount% DV
Bovine Liver3000 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

For most of human history, we consumed the whole animal (nose-to-tail) with deep respect and profound purpose. For instance, Native Americans and early ancestral healers believed that eating the organs from a healthy animal would strengthen and support the health of the corresponding organ of the individual-Also known as "like supports like." The traditional way of treating a person with a weak heart was to feed the person the heart of a healthy animal. Since we've abandoned these ways, the modern world has left us malnourished with an epidemic of declining health. The solution is to find ways to recreate our ancestral environment (sleep, nourishment, movement, sunshine, etc). It's time we honor our ancestors by putting back in, what the modern world has left out (To return our people back to strength, health and happiness). We walk our talk and we offer a one-of-a-kind "guided" experience. Learn more at www.ancestralsupplements.com Brian Johnson "Liver King"

One small batch at a time.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Pasture raised in New Zealand & Australia Grass-Fed & Grass-Finished

Hormone, pesticide & GMO free Absolutely no fillers (or) flow agents

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 6 capsules daily or as directed by a healthcare professional.

Formula

Grassfed Beef Liver 180 capsules 500 mg ea

See for yourself

Grassfed Beef Liver by Ancestral Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Grassfed Beef Liver by Ancestral Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Bovine Liver

Interacts with
3 drugs
3000 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Bovine Liver monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Grassfed Beef Liver by Ancestral Supplements Drug Interactions

Want to check YOUR meds against Grassfed Beef Liver?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Grassfed Beef Liver with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bovine Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Grassfed Beef Liver, from the product label.

Ancestral Supplements

See all Ancestral Supplements products
Name
Ancestral Supplements, LLC
City
Spring
State
TX
ZipCode
77379
Web Address
www.ancestralsupplements.com
Pharmacist Counseling Corner

Grassfed Beef Liver by Ancestral Supplements: Common Questions

Does Grassfed Beef Liver by Ancestral Supplements interact with any medications?
Yes. Based on its ingredients, Grassfed Beef Liver has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Grassfed Beef Liver contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without checking with your pharmacist first. Liver extract contains vitamin K, which can interfere with how warfarin works and lower your INR. The interaction hasn't been directly studied, so we can't say exactly how much risk applies to you — that's why your pharmacist needs to weigh your specific dose and situation.
Is it safe to take with iron supplements?
Be cautious. Liver extract contains heme iron, so combining it with iron pills or supplements raises your total iron intake. That can cause stomach upset or, with high doses over time, iron buildup in your body. Talk to your pharmacist, especially if you have hemochromatosis or another iron-storage condition.
Can I take this while pregnant?
The safety data advises against it. Liver products contain very high levels of vitamin A, which may harm a developing baby. Don't start unless your doctor specifically advises it.
Does beef liver actually work for chronic fatigue?
The evidence doesn't support it. For chronic fatigue syndrome, it's rated possibly ineffective in the data we hold. If you're considering it for another reason, let us know — we may have different information for that use.
Where does this liver come from, and is BSE a real concern?
Liver extract comes from raw animal liver at slaughterhouses. Mad cow disease (BSE) has been reported in cattle from Great Britain, France, The Netherlands, Portugal, Luxembourg, Ireland, Switzerland, Oman, and Belgium. No human cases from contaminated liver extract have been reported, but until more is known, check the product label or ask the manufacturer which country the cattle came from.
What's in the capsule besides liver?
Gelatin is the only other ingredient listed — that's the capsule material itself. There are no added fillers or binders.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Grassfed Beef Liver is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Grassfed Beef Liver label
Sources

Sources & How We Checked

Grassfed Beef Liver's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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