Green Lipped Mussels Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Green Lipped Mussels against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Green Lipped Mussels is a dietary supplement by Fresh Nutrition with 1 active ingredient. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis symptoms, joint stiffness and mobility.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Green Lipped Mussels by Fresh Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: New Zealand green-lipped mussel, a shellfish-derived source. The capsule itself is vegetarian.
Does it work?
Not established
The evidence for green-lipped mussel isn't established in the data we hold. The ingredient has been studied for asthma, ADHD, breast cancer, and exercise-related muscle soreness, but the available evidence is insufficient to rate whether it actually works for any of these uses.
How safe is it?
Well-documented data
New Zealand green-lipped mussel is generally well tolerated. The most common side effects are abdominal pain, acid reflux, diarrhea, flatulence, and nausea — mild digestive complaints that some people experience.
Rarely, serious liver problems have been reported, including hepatitis and liver function abnormalities, though these cases are uncommon. If you have a shellfish allergy, avoid this product.
The ingredient is derived from shellfish, so it's not safe for you. Pregnant people should avoid it — there isn't enough safety data to know it's okay.
Breastfeeding is also not recommended, since safety hasn't been established.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we checked. That doesn't mean interactions can't happen — just that we have no documented ones on file.
Check your exact medications with the tool on this page to be safe.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
Green-lipped mussel might be worth considering if you're curious about its potential benefits, but keep in mind the evidence for it isn't solid yet. If you're pregnant, breastfeeding, or allergic to shellfish, skip it.
Anyone else should talk with their pharmacist before starting, especially if they have liver concerns or a history of digestive upset.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Green Lipped Mussels, straight from the product label.
| Brand | Fresh Nutrition |
|---|---|
| Barcode (UPC) | 850008467196 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 22, 2021 |
| DSLD ID | 241967 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Green Lipped Mussels by Fresh Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Green Lipped Mussel | 500 mg | -- |
Other ingredients: Vegetarian Capsules
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Non GMO Gluten free Soy free
No artificial colors. No artificial flavors. No preservatives. Made with Non-GMO, all natural ingredients!
Vegan
All natural
May help stronger respiration May enhance range of motion May assist joint health
Fresh Nutrition produces the most potent and highest quality Green Lipped Mussels. Our raw materials are carefully sourced and cultivated; contain no fillers, additives, and are manufactured domestically in a cGMP facility. Thank you for choosing Fresh!
Formula
Green Lipped Mussels Known as 'Greenshell', these mussels are native to New Zealand, and contain properties and nutrients that can improve your overall health and quality of life. These nutrients have been shown to ease joint pain and increase air flow, so not only will you move easier, but you'll also breathe easier.
Made with Non-GMO, all natural ingredients!
Made with New Zealand green mussels Source of omega-3 fatty acids
General Statements
Fresh Nutrition Our goal is to create high-quality natural products using both organic and responsibly sourced ingredients to optimize health and well-being.
Suggested/Recommended/Usage/Directions
Recommended Dosage Take three (3) capsules daily with sufficient water before a meal.
Seals/Symbols
Quality Verified Third Party Tested For Quality And Purity To provide our consumers with complete confidence in our product quality, every batch is 3rd party tested for quality & purity.
Made in USA
GMP Manufactured in a GMP registered facility
FDA Statement of Identity
Dietary Supplement
Precautions
Do not use this product if you are pregnant or nursing, or if you have a history of gallstones or bile duct obstruction. Consult with your physician prior to taking this product if you are taking medication which may affect blood clotting, or if you plan to have surgery.
Allergy Warning: Contains fish and shellfish.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Green Lipped Mussels by Fresh Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Green Lipped Mussels by Fresh Nutrition
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Green Lipped Mussel
No knowninteractions
New Zealand green-lipped mussel is a shellfish-derived supplement rich in omega-3 fats that is mostly used for joint pain and arthritis. Some studies...
Green Lipped Mussel monograph & interactionsOther (inactive) ingredients: Vegetarian Capsules. These complete the product’s ingredient list but are not active constituents.
Green Lipped Mussels by Fresh Nutrition Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Green Lipped Mussels. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Green Lipped Mussels, from the product label.
Fresh Nutrition
See all Fresh Nutrition products- Name
- Fresh Nutrition
- Street Address
- 1601 Dove St
- City
- Newport Beach
- State
- California
- ZipCode
- 92660
- Web Address
- www.fresh-nutrition.com
Green Lipped Mussels by Fresh Nutrition: Common Questions
Does Green Lipped Mussels by Fresh Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I have a shellfish allergy?
Is it safe to use while pregnant or breastfeeding?
What side effects might I notice?
Does green-lipped mussel actually work for asthma or muscle soreness?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Green Lipped Mussels is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Green Lipped Mussels’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Green Lipped Mussels's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
New Zealand Green-lipped Mussel 12 references
- Miller T, Wu H. In vivo evidence for prostaglandin inhibitory activity in New Zealand green-lipped mussel extract. N Z Med J 1984;97:355-7.
- Gibson SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus: a randomised trial. Complement Ther Med 1998;6:122-6.
- Gibson RG, Gibson SL, Conway V, Chappell D. Perna canaliculus in the treatment of arthritis. Practitioner 1980;224:955-60.
- Fabrin, B. [Possible toxic hepatitis after intake of an alternative preparation]. Ugeskr.Laeger 6-13-1988;150(24):1474-1475.
- Gibson, R. G. and Gibson, S. L. Green-lipped mussel extract in arthritis. Lancet 2-21-1981;1(8217):439. PubMed
- Ahern, M. J., Milazzo, S. C., and Dymock, R. Granulomatous hepatitis and Seatone. Med J Aust 8-9-1980;2(3):151-152. PubMed
- Croft, J. E. Granulomatous hepatitis and Seatone. Med J Aust 10-4-1980;2(7):401-402. PubMed
- Lau, S., Chiu, P. K., Chu, E. M. Y., Cheng, I. Y. W., Tang, W. M., Man, R. Y. K., and Halpern, G. M. Treatment of knee osteoarthritis with Lyprinol, lipid extract of the green-lipped mussel - a double-blind placebo-controlled study. Progress in Nutrition
- Gruenwald, J., Graubaum, H., Hansen, K., and Grube, B. Efficacy and tolerability of a combination of LYPRINOL and high concentrations of EPA and DHA in inflammatory rheumatoid disorders... eicosapentaenoic acid... decosahexaenoid acid. Advances in Therap PubMed
- Coulson S, Vecchio P, Gramotnev H, Vitetta L. Green-lipped mussel (Perna canaliculus) extract efficacy in knee osteoarthritis and improvement in gastrointestinal dysfunction: a pilot study. Inflammopharmacology 2012;20:71-6. PubMed
- Sukumaran S, Pittman KB, Patterson WK, et al. A phase I study to determine the safety, tolerability and maximum tolerated dose of green-lipped mussel (Perna canaliculus) lipid extract, in patients with advanced prostate and breast cancer. Ann Oncol 2010;2 PubMed
- Lello J, Liang A, Robinson E, et al. Treatment of children's asthma with a lipid extract of the new Zealand green lipped mussel (Perna canaliculus) (Lyprinol®)-A double blind, randomized controlled trial in children with moderate to serve chronic obstruct
See these in context on the New Zealand Green-lipped Mussel monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC