Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

He Ye Ingredients & Drug Interactions

by Herbal Terra

He Ye label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking He Ye against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

He Ye is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for digestive upset and diarrhea, anxiety and relaxation, sleep support.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Nelumbo nucifera Leaf Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against He Ye by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with He Ye by Herbal Terra — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of He Ye by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 1 active ingredient: lotus leaf extract (from Nelumbo nucifera). Lotus is a traditional herb used in Asian medicine.

The liquid also contains alcohol, water, and glycerin as inactive ingredients to preserve and deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lotus product and its label doesn't state a use — see Lotus's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for lotus leaf extract isn't established in our data. The product has been studied for nausea, sore throat, insomnia, weight management, heavy periods, and bleeding, but the data we hold shows insufficient reliable evidence to rate it for any of these uses.

That doesn't mean it doesn't work—just that the science we have on file isn't conclusive yet.

The evidence, ingredient by ingredient Lotus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lotus is common as a food, but when used as a concentrated supplement, safety hasn't been well studied in humans. You should avoid medicinal doses of lotus supplements because we don't have enough safety data yet.

Allergic reactions like hives and skin rashes have been reported, especially after eating lotus root. Don't use this supplement while breastfeeding—there isn't enough safety data.

For pregnancy, safety data isn't on file, so talk with your pharmacist or doctor before using it.

Side effects, ingredient by ingredient Lotus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lotus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against lotus before starting, especially if you take blood thinners or antiplatelet drugs (risk of bleeding), antidiabetes medications (risk of low blood sugar), or pentobarbital or other sedatives.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you eat lotus as a food, that's different from this concentrated supplement. This product might interest someone looking for traditional herbal support, but if you take blood thinners, diabetes drugs, or barbiturate sedatives, you'll need to check with us first.

Talk with your pharmacist before starting—especially if you're pregnant, breastfeeding, or have a history of allergic reactions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about He Ye, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7238360251388
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 325089
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for He Ye by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7238360251388
IngredientAmount% DV
Nelumbo nucifera Leaf Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Nelumbo nucifera

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

He Ye by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

He Ye label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in He Ye by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Nelumbo nucifera Leaf Extract, Dry

Interacts with
212 drugs
983 mg per serving

Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for digestion...

Nelumbo nucifera Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

He Ye by Herbal Terra Drug Interactions

Want to check YOUR meds against He Ye?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Nelumbo nucifera Leaf Extract, Dry 212

Individual Drug Interactions

The ingredients in He Ye interact with 212 drugs. Click any drug to see the details.

1 of the 1 ingredient in He Ye interact with drugs. Each result below shows which ingredient is responsible. Nelumbo nucifera Leaf Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in He Ye with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Nelumbo nucifera Leaf Extract, Dry3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concurrent use of lotus with other antiplatelet drugs might reduce platelet aggregation and increase the risk of bleeding.
Neferine and isoliensinine, constituents of lotus, have been shown to inhibit platelet aggregation, in vitro. These constituents can inhibit the production of pro-aggregating factors like prostaglandins.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lotus might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Animal research shows that the ethanolic extract of lotus reduces blood glucose levels and potentiates the effects of injected insulin. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, taking lotus concomitantly with pentobarbital might increase sedation.
Animal research shows that lotus extract increases pentobarbitone-induced sleeping time. It is not known if this occurs in humans or if this effect occurs with other barbiturates or sedatives.

Likelihood Possible Evidence D
Nelumbo nucifera Leaf Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for He Ye, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

He Ye by Herbal Terra: Common Questions

Does He Ye by Herbal Terra interact with any medications?
Yes. Based on its ingredients, He Ye has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
He Ye contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's in this He Ye liquid?
It's lotus leaf extract plus alcohol, water, and glycerin. The lotus leaf comes from Nelumbo nucifera, a water lily used in traditional Asian medicine.
Can I take this while pregnant?
Safety data for lotus in pregnancy isn't on file. Talk with your pharmacist or doctor before using it—they can give you personalized advice.
Can I take this while breastfeeding?
No, safety data advises against using this supplement while breastfeeding. There isn't enough information to know it's safe for your baby.
Can lotus cause allergic reactions?
Yes. Hives and skin rashes have been reported, especially after eating lotus root. Stop and see a doctor if you develop a rash or itching.
Is this proven to work for insomnia or weight loss?
The evidence we hold shows insufficient reliable data to rate lotus for those uses yet. That doesn't mean it won't help—just that we don't have solid proof on file.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if He Ye is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

He Ye label
Go deeper

The Full Monographs Behind He Ye’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lotus

Interacts with 212 drugs

Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for digestion, calm, and overall wellness. Most healt...

Read the full Lotus monograph →
Sources

Sources & How We Checked

He Ye's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lotus 5 references
  1. Yu, J. and Hu, W. S. [Effects of neferine on platelet aggregation in rabbits]. Yao Xue.Xue.Bao. 1997;32(1):1-4.
  2. Yang, J. and Zhou, K. NMR spectroscopic analysis of neferine and isoliensinine. Magn Reson.Chem 2004;42(11):994-997. PubMed
  3. Mukherjee, P. K., Saha, K., Balasubramanian, R., Pal, M., and Saha, B. P. Studies on psychopharmacological effects of Nelumbo nucifera Gaertn. rhizome extract. J Ethnopharmacol. 1996;54(2-3):63-67. PubMed
  4. Mukherjee, P. K., Saha, K., Pal, M., and Saha, B. P. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. J Ethnopharmacol. 1997;58(3):207-213. PubMed
  5. Hiraguchi Y, Tokuda R, Gen M, et al. Identification of a novel food allergen in lotus root. Allergol Int. 2018;67(1):141-143. PubMed

See these in context on the Lotus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team