No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Heartsease Ingredients & Drug Interactions

by Hawaii Pharm

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Heartsease is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for skin conditions like eczema and cradle cap, mild respiratory complaints (cough), mild inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Heartsease by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: heartsease extract. We don't have detailed information on what role it plays in the body, but traditionally it's been used for respiratory and skin health.

The liquid also contains vegetable palm glycerin, pharmaceutical-grade alcohol, and artesian Hawaiian purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Heart's Ease product and its label doesn't state a use — see Heart's Ease's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold isn't strong enough to say whether heartsease works for chronic obstructive pulmonary disease (COPD) or atopic dermatitis (eczema, a chronic itchy skin condition). The rating for both is insufficient reliable evidence to rate — meaning studies either don't exist, are too small, or don't clearly show a benefit.

That's not a verdict that it doesn't work, just that we can't confirm it from the data.

The evidence, ingredient by ingredient Heart's Ease

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Heartsease is generally well tolerated when taken by mouth. The safety data are limited, though, so we don't have a complete picture of how safe it is long-term or in all groups.

One important note: there's a case report of hemolysis (the breakdown of red blood cells) in a nine-month-old infant with glucose-6-phosphate-dehydrogenase (G6PD) deficiency, a genetic condition affecting how blood cells handle certain substances. If you or a family member has G6PD deficiency, talk to your doctor or pharmacist before using this product.

There isn't enough safety information to know if heartsease is safe during pregnancy or while breastfeeding. Because of that, the data advise against using it in those times.

If you're pregnant, nursing, or planning to be, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Heart's Ease

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, before you start this product, run your full medication list through the search tool on this page — absence of documented interactions isn't a guarantee none exist.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Heartsease extract is generally well tolerated, but the evidence for what it actually does isn't established in our data. It's not recommended during pregnancy or breastfeeding due to limited safety information, and anyone with G6PD deficiency should check with their doctor or pharmacist first.

If you're considering it, talk it over with your doctor or pharmacist to decide if it fits your health plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Heartsease, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 650905459313
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 237258
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Heartsease by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
650905459313
IngredientAmount% DV
Heartsease extract970 mg--

Other ingredients: Vegetable Palm Glycerin, pharmaceutical grade Alcohol, artesian Hawaiian purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Formula

(Viola tricolor)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

See for yourself

Heartsease by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Heartsease by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Heartsease extract

No known
interactions
970 mg per serving

Heart's Ease (Viola tricolor) is a traditional European herb used mostly for skin problems and mild coughs. Modern human evidence for these uses is ve...

Heartsease extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Pharmaceutical grade Alcohol, Artesian Hawaiian purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Heartsease by Hawaii Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Heartsease. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Heartsease, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Heartsease by Hawaii Pharm: Common Questions

Does Heartsease by Hawaii Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Heartsease. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Heartsease contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety information isn't there to say it's okay during pregnancy or breastfeeding, so it's best avoided in those times. Talk with your doctor or pharmacist for personalized advice about whether this product is right for you.
What is heartsease used for?
Traditionally it's been used for respiratory and skin health. The evidence we hold isn't strong enough to confirm it works for chronic obstructive pulmonary disease (COPD) or atopic dermatitis (eczema).
Does heartsease have side effects?
Most people tolerate it well by mouth. One important case: a nine-month-old infant with a genetic condition called glucose-6-phosphate-dehydrogenase (G6PD) deficiency had hemolysis (red blood cell breakdown) from it. If you or a family member has G6PD deficiency, check with your doctor or pharmacist before using this product.
Is the alcohol content high enough to worry about?
The product does contain pharmaceutical-grade alcohol as an inactive ingredient, but we don't have data on the exact concentration. If alcohol content is a concern for you, check the label or ask your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Heartsease is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Heartsease label
Go deeper

The Full Monographs Behind Heartsease’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Heartsease's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Heart's Ease 4 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Behmanesh Y, Abdollahi M. Hemolysis after consumption of Viola tricolor. WHO Drug Inf (Iran) 2002;16:15-16.
  3. Klovekorn, W., Tepe, A., and Danesch, U. A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatit
  4. Kirichenko TV, Sobenin IA, Markina YV, et al. Clinical effectiveness of a combination of black elder berries, violet herb, and calendula flowers in chronic obstructive pulmonary disease: the results of a double-blinded placebo-controlled study. Biology (B PubMed

See these in context on the Heart's Ease monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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