No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Herbal Actives Olive Leaf 250 MG/6% Oleuropein Ingredients & Drug Interactions

by Nature's Plus

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Herbal Actives Olive Leaf 250 MG/6% Oleuropein is a dietary supplement by Nature's Plus with 1 active ingredient. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Herbal Actives Olive Leaf 250 MG/6% Oleuropein by Nature's Plus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: olive leaf extract, standardized to 6% oleuropein. Oleuropein is the compound researchers believe carries olive leaf's potential effects — it's been studied for a range of concerns, from bone health to immune function, though the evidence for most of those uses remains limited.

The capsule also contains inactive ingredients (microcrystalline cellulose, silica, vegetable cellulose, and purified water) that help hold the supplement together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Olive product and its label doesn't state a use — see Olive's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for olive leaf extract isn't established yet. Our data rates it as having insufficient reliable evidence for osteoporosis, gastroesophageal reflux disease (GERD), exercise-induced respiratory infections, herpes zoster (shingles), influenza, and osteoarthritis — the conditions it's most often promoted for.

That means researchers haven't done enough high-quality trials to say whether it works for any of these uses. If you're thinking about trying it for a specific condition, it's worth discussing with your doctor to see whether there's a better-studied option.

The evidence, ingredient by ingredient Olive

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive as a food and oil is very safe, but concentrated supplements like this one are less studied, so caution is warranted. Most people tolerate olive leaf extract well.

The most common side effects reported in trials are headache and stomach discomfort. One person in a trial reported skin problems and acne.

Additionally, if you have seasonal allergies to olive tree pollen, this supplement might trigger or worsen those symptoms. Our data doesn't include pregnancy and lactation safety information for this ingredient.

There isn't enough data to know whether it's safe during pregnancy or breastfeeding, so talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient Olive

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for olive leaf extract in our data. You're clear on that front — but it's still smart to mention any new supplement to your own doctor or pharmacist before you start taking it regularly.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Olive leaf extract is generally well tolerated and carries no documented medication interactions, but the evidence for what it actually does is limited. If you're considering it for bone health, digestive issues, immune support, or any other condition, check with your doctor first — they may recommend something with stronger evidence behind it.

Mention this supplement to your pharmacist or doctor before starting, especially if you have seasonal allergies or take any regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Herbal Actives Olive Leaf 250 MG/6% Oleuropein, straight from the product label.

Brand Nature's Plus
Barcode (UPC) 097467072343
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 1, 2012
DSLD ID 13774
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Herbal Actives Olive Leaf 250 MG/6% Oleuropein by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
097467072343
IngredientAmount% DV
Olive Leaf extract250 mg--

Other ingredients: Microcrystalline Cellulose, Silica, Vegetable Cellulose, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Note: If you are pregnant or nursing, consult your health care professional before using any herbal product.

THIS IS NOT A PRESCRIPTION PRODUCT. It is a dietary supplement made with the highest possible quality standards.

Printed HerbaShield inner seal and full bottle seal. Do not use if either seal is missing or broken.

KEEP OUT OF REACH OF CHILDREN.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

HerbaShield(R)

GLUTEN Free

MAXIMUM GUARANTEED POTENCY(R)

Formulation

Free from artificial colors and preservatives. Free from the common allergens yeast, wheat, corn, soy and milk.

Formula

HYPO-ALLERGENIC.

Storage

KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.

Brand IP Statement(s)

Vcaps(TM) is a trademark of Capsugel(R), a division of Pfizer, Inc.

(C)NATURAL ORGANICS(R)

The Energy Supplements(R)

General Statements

Nutritional Support for General Well-Being.* Each Herbal Actives Olive Leaf capsule, providing the greatest concentration of active botanical principles, maximizes the synergistic benefits of the whole leaf, which naturally contains calcium elenolate and numerous phytonutrients. Guaranteed Maximum Potency: Each Herbal Actives formula is scientifically standardized to the highest level of active principles. HerbaShield: An exclusive purity and safety system including light-resistant bottle, airtight inner seal, moisture-absorbing packet, tamper-evident safety cap and tamper-proof full bottle seal.

PRESCRIPTION QUALITY

FDA Statement of Identity

STANDARDIZED BOTANICAL SUPPLEMENT

General

PRODUCT NO. 7234 LBL. 1128961

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement offering the consistent benefits of exact potency, one capsule daily or as recommended by your health care professional.

See for yourself

Herbal Actives Olive Leaf 250 MG/6% Oleuropein by Nature's Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Herbal Actives Olive Leaf 250 MG/6% Oleuropein by Nature's Plus

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Olive Leaf extract

No known
interactions
250 mg per serving Form: Oleuropein

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive Leaf extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Silica, Vegetable Cellulose, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Herbal Actives Olive Leaf 250 MG/6% Oleuropein by Nature's Plus Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Herbal Actives Olive Leaf 250 MG/6% Oleuropein. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Herbal Actives Olive Leaf 250 MG/6% Oleuropein, from the product label.

Nature's Plus

See all Nature's Plus products
Name
Natural Organics Laboratories, Inc. makers of Nature's Plus
Street Address
9500 New Horizons Blvd.
City
Amityville
State
New York
ZipCode
11701
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Herbal Actives Olive Leaf 250 MG/6% Oleuropein by Nature's Plus: Common Questions

Does Herbal Actives Olive Leaf 250 MG/6% Oleuropein by Nature's Plus interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Herbal Actives Olive Leaf 250 MG/6% Oleuropein. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Herbal Actives Olive Leaf 250 MG/6% Oleuropein contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is oleuropein, and why is it in this product?
Oleuropein is the main active compound in olive leaves. It's the ingredient researchers believe may be responsible for olive leaf's potential health effects. This product is standardized to 6% oleuropein to ensure you're getting a consistent dose.
Is olive leaf extract safe to take long-term?
Olive as a food and oil is very safe, but concentrated supplements haven't been studied as thoroughly. Most people who take olive leaf extract tolerate it well, but because the long-term safety data is thinner than for whole foods, it's a good idea to check with your doctor before using it regularly.
What side effects might I experience?
Headache and stomach discomfort are the most common ones people report in trials. One person reported skin problems and acne. If you're allergic to olive tree pollen, this supplement might worsen seasonal allergies.
Does this product actually work for the conditions it's marketed for?
Our data shows insufficient reliable evidence for olive leaf extract to rate its effectiveness for osteoporosis, GERD, immune support, shingles, flu, or osteoarthritis. That means there haven't been enough solid clinical trials to say it works. Your doctor can help you find options with stronger evidence if you're dealing with one of these conditions.
Can I take this while pregnant or breastfeeding?
We don't have safety data on file for olive leaf extract during pregnancy or lactation. There isn't enough information to know either way, so talk with your doctor or pharmacist for advice tailored to your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Herbal Actives Olive Leaf 250 MG/6% Oleuropein is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Herbal Actives Olive Leaf 250 MG/6% Oleuropein label
Go deeper

The Full Monographs Behind Herbal Actives Olive Leaf 250 MG/6% Oleuropein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Herbal Actives Olive Leaf 250 MG/6% Oleuropein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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