No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

High Potency Biotin 2500 mcg Ingredients & Drug Interactions

by Nature Made

Softgel Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

High Potency Biotin 2500 mcg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of High Potency Biotin 2500 mcg by Nature Made

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 1 active ingredient: biotin, a B vitamin your body needs to convert food into energy and maintain healthy hair, skin, and nails. The remaining ingredients are inactive—soybean oil, gelatin, glycerin, and others that form the softgel capsule and preserve the product.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Healthy hair, skin and nails.
  • We looked for evidence on: Biotin deficiency, Brittle nails, Hair loss, Nail health, Skin condition.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for treating biotin deficiency itself. For multiple sclerosis and seborrheic dermatitis (a flaky, itchy scalp condition), the evidence suggests it's probably not effective.

For alopecia areata (patchy hair loss), there isn't enough reliable evidence to say whether it works or not. Most people take biotin hoping it'll strengthen hair and nails, but the data on file here doesn't cover that use.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body excretes excess in urine. High-dose biotin has rarely been linked to mild diarrhea—in trials, 2 patients taking 300 mg daily reported transient mild diarrhea.

One isolated case report described a woman who developed a rare heart and lung inflammation after taking biotin 10 mg plus pantothenic acid 300 mg daily for 2 months while on other medications; whether biotin itself was the cause remains unclear, and no similar cases have been reported since. Because this is a high-dose supplement, talk with your doctor before starting it.

Biotin is likely safe in pregnancy and lactation, including the amounts in prenatal vitamins, but discuss high-dose products with your doctor first.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the biotin in this product. That said, absence of documented interactions is not a guarantee none exist—check your specific medications with the search tool on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have a documented biotin deficiency, this product is likely to help. For other uses like hair or nail strength, the evidence on file doesn't support its effectiveness.

This is a high-dose supplement, so check with your doctor or pharmacist before taking it, especially if you're on any medications. A quick run-through of your drug list with the tool on this page will give you peace of mind.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High Potency Biotin 2500 mcg, straight from the product label.

Brand Nature Made
Net contents 90 Liquid Softgel(s)
Market status On market
Date entered into DSLD Oct 25, 2013
DSLD ID 26644
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High Potency Biotin 2500 mcg by Nature Made, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
IngredientAmount% DV
Biotin2500 mcg833%

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Water, Soy Lecithin, Artificial Colors, Fruit and Vegetable Juice, Maltodextrin, Citric Acid, Sodium Hydroxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Biotin 2500 mcg Liquid Softgel

General Statements

#1 PHARMACIST RECOMMENDED 50% MORE FREE

HIGH POTENCY

For Healthy Hair, Skin & Nails

FDA Statement of Identity

DIETARY SUPPLEMENT

Precautions

As ingredients may change from time to time, please check the label on the bottle.

Formulation

No Gluten. No Starch. No Yeast. No Preservatives. No Artificial Flavors.

Seals/Symbols

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See for yourself

High Potency Biotin 2500 mcg by Nature Made label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in High Potency Biotin 2500 mcg by Nature Made

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Biotin

No known
interactions
2500 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Water, Soy Lecithin, Artificial Colors, Fruit and Vegetable Juice, Maltodextrin, Citric Acid, Sodium Hydroxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

High Potency Biotin 2500 mcg by Nature Made Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in High Potency Biotin 2500 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for High Potency Biotin 2500 mcg, from the product label.

Nature Made

See all Nature Made products
Name
Nature Made
Pharmacist Counseling Corner

High Potency Biotin 2500 mcg by Nature Made: Common Questions

Does High Potency Biotin 2500 mcg by Nature Made interact with any medications?
We do not currently list a known interaction for the mapped ingredients in High Potency Biotin 2500 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
High Potency Biotin 2500 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will biotin help my hair grow or stop it from falling out?
The data we hold doesn't establish whether biotin works for hair strength or regrowth. Biotin is likely effective only for treating an actual biotin deficiency. If hair loss is a concern, talk with your doctor about what might help.
Is this safe to take while pregnant or breastfeeding?
Biotin is likely safe during pregnancy and lactation, including the smaller amounts in prenatal vitamins. But this is a high-dose product—2500 micrograms is well above dietary levels—so check with your doctor before taking it while pregnant or nursing.
What are the side effects of high-dose biotin?
High-dose biotin is rarely linked to side effects. Mild diarrhea has been reported in a small number of people taking very high doses (300 mg daily). One isolated case report described heart and lung inflammation in a woman taking biotin plus other supplements and medications, but it's unclear whether biotin was the cause.
Can I take this if I have multiple sclerosis or seborrheic dermatitis?
Biotin is probably not effective for either condition, according to the evidence we hold. If you have MS or a flaky, itchy scalp, talk with your doctor about treatments that are proven to work.
Why is this product so much higher in biotin than I'd get from food?
Food-based biotin ranges from trace amounts to a few micrograms per serving. This product delivers 2500 micrograms, which is why it's labeled 'high potency'—and also why your doctor should weigh in before you start it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High Potency Biotin 2500 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High Potency Biotin 2500 mcg label
Go deeper

The Full Monographs Behind High Potency Biotin 2500 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

High Potency Biotin 2500 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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