No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

High Potency Biotin 2500 mcg Ingredients & Drug Interactions

by Nature Made

Softgel Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

High Potency Biotin 2500 mcg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of High Potency Biotin 2500 mcg by Nature Made

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin at 2500 micrograms (mcg) per softgel. Biotin is a B vitamin that your body uses to break down fats, carbohydrates, and amino acids.

The softgel also contains inactive ingredients — soybean oil, gelatin, glycerin, yellow beeswax, water, soy lecithin, and added colors — that make up the capsule and help deliver the biotin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support healthy hair, skin and nails.
  • We looked for evidence on: Biotin deficiency, Brittle nails, Hair loss, Skin quality.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for treating biotin deficiency, a genuine shortage of the vitamin in your body. For other uses — hair loss (alopecia areata), seborrheic dermatitis (a scaly skin condition), or multiple sclerosis — the evidence we hold shows either possibly ineffective or insufficient evidence to rate it.

If you're considering this supplement for a specific condition, talk with your doctor about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at higher doses, because your body excretes excess amounts in urine. High-dose biotin has rarely been linked to mild diarrhea in isolated cases.

One unusual case report described a woman on a very high dose who developed a rare inflammatory condition, but whether biotin was responsible is unclear, and no similar cases have been reported since. Because this is a high-dose product, check with your doctor before starting it — normal dietary amounts and those in prenatal vitamins are fine, but high-dose supplements warrant a conversation first.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for biotin. That said, it's always smart to show your doctor or pharmacist the label before adding any new supplement to your routine.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This biotin supplement is useful if you have a documented biotin deficiency. If you're taking it for hair, skin, or neurological concerns, the evidence for those uses is weak or unproven — your doctor can help you decide if it's worth trying.

Talk with your doctor or pharmacist before you start, especially since this is a high-dose formulation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High Potency Biotin 2500 mcg, straight from the product label.

Brand Nature Made
Barcode (UPC) 031604029173
Net contents 150 Softgel(s)
Market status On market
Date entered into DSLD Aug 31, 2018
DSLD ID 179952
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High Potency Biotin 2500 mcg by Nature Made, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
031604029173
IngredientAmount% DV
Biotin2500 mcg833%

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Water, Soy Lecithin, Colors added

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Value size #1 pharmacist recommended

May help support healthy hair, skin and nails

Biotin may help support healthy hair, skin and nails in those that are biotin deficient. Biotin also supports carbohydrate, protein & fat metabolism.

USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.

General

List No. 2917 L201 Cat. A521 5A044

Formula

High Potency Biotin 2500 mcg

Contains: Soy.

Seals/Symbols

USP Dietary Supplement Verified

FDA Statement of Identity

Dietary Supplement

Formulation

Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Suggested/Recommended/Usage/Directions

Suggested use: Take one softgel daily with a meal. For easier swallowing, take with water before and during ingestion.

Storage

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Contains: Soy.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

High Potency Biotin 2500 mcg by Nature Made label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in High Potency Biotin 2500 mcg by Nature Made

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Biotin

No known
interactions
2500 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Water, Soy Lecithin, Colors added. These complete the product’s ingredient list but are not active constituents.

Interaction report

High Potency Biotin 2500 mcg by Nature Made Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in High Potency Biotin 2500 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for High Potency Biotin 2500 mcg, from the product label.

Nature Made

See all Nature Made products
Name
Nature Made Nutritional Products
City
Mission Hills
State
CA
ZipCode
91346-9606
Phone Number
1-800-276-2878
Web Address
www.NatureMade.com
Pharmacist Counseling Corner

High Potency Biotin 2500 mcg by Nature Made: Common Questions

Does High Potency Biotin 2500 mcg by Nature Made interact with any medications?
We do not currently list a known interaction for the mapped ingredients in High Potency Biotin 2500 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
High Potency Biotin 2500 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe to take while I'm pregnant or breastfeeding?
Biotin is rated likely safe in pregnancy and lactation. Normal dietary amounts and prenatal vitamin amounts are fine. But since this is a high-dose supplement, run it by your doctor or midwife first to make sure it's right for you.
Will biotin help my hair grow back or stop it from falling out?
The evidence for biotin in alopecia areata (patchy hair loss) is insufficient — we don't have enough reliable data to say whether it works. If hair loss is a concern, talk with your doctor about proven options.
What side effects should I watch for?
High-dose biotin is rarely associated with mild diarrhea. One isolated case report described a more serious condition, but it's unclear whether biotin was the cause, and no similar cases have been reported since. Most people tolerate it without problems.
Can I take this if I'm on blood thinners or other medications?
No interactions are documented in our data for biotin. Still, check with your pharmacist or doctor before adding any new supplement to your routine — they can confirm it's safe alongside your specific medications.
Why does the label say to check with my doctor before taking this?
Because this is a high-dose biotin product, not the amount you'd normally get from food or a standard vitamin. Your doctor can confirm it's appropriate for you and won't interfere with anything else you're taking.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High Potency Biotin 2500 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High Potency Biotin 2500 mcg label
Go deeper

The Full Monographs Behind High Potency Biotin 2500 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

High Potency Biotin 2500 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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