Hist-D Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hist-D against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hist-D is a dietary supplement by Adaptogen Research with 1 active ingredient.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Hist-D by Adaptogen Research
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hist-D, straight from the product label.
| Brand | Adaptogen Research |
|---|---|
| Barcode (UPC) | 722537501699 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 22, 2024 |
| DSLD ID | 307150 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hist-D by Adaptogen Research, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Diamine Oxidase | 600 mcg | -- |
Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Sucrose, Ascorbic Acid, Rice Starch, Shellac, Hydroxypropyl Cellulose, Polyvinylpolypyrrolidone, Magnesium Silicate, Hydrated, Acetylated Corn Starch, Sodium Carboxymethyclellose, Glycerol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Take one to two capsules no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare professional.
Precautions
Consult your healthcare professional prior to use. Do not use if tamper seal is damaged.
Individuals taking medication should discuss potential interactions with their healthcare professional.
Avoid if allergic to pork or any other ingredient. Hist-D is not effective for symptoms of immune-related food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease.
Hist-D does not manage or address antibody-related or IgE-related food allergies.
Professional use only
Report any adverse reaction to adaptogenresearch.com
Formula
Hist-D is a patented enzyme formula containing diamine oxidase (DAO) - the main enzyme responsible for the degradation of ingested histamine. This enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract. DAO is not absorbed and does not have systemic activity. Hist-D does not manage or address antibody-related or IgE-related food allergies.
Brand IP Statement(s)
Hist-D is a patented enzyme formula containing diamine oxidase (DAO) - the main enzyme responsible for the degradation of ingested histamine.
Hist-D is exclusively manufactured for healthcare professionals under license of Sciotec Diagnostic Technologies GmbH, Vienna, Austria. Patented in Austria. Patent pending in the United States.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Storage: Keep closed in a cool, dry place out of reach of children.
Formulation
Formulated to exclude: wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, and artificial preservatives. Made with Non-GMO ingredients Does not contain gluten
Vegetarian Formula
Supports healthy degradation of food-derived histamine
Manufactured in a GMP compliant facility
Vegetarian caps
Seals/Symbols
Vegetarian Formula Made with Non-GMO ingredients
Guaranteed GMP Compliant Products
FDA Statement of Identity
Dietary Supplement
General Statements
This package is completely recyclable
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hist-D by Adaptogen Research label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hist-D by Adaptogen Research
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Diamine Oxidase
Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Sucrose, Ascorbic Acid, Rice Starch, Shellac, Hydroxypropyl Cellulose, Polyvinylpolypyrrolidone, Magnesium Silicate, Hydrated, Acetylated Corn Starch, Sodium Carboxymethyclellose, Glycerol. These complete the product’s ingredient list but are not active constituents.
Hist-D by Adaptogen Research Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Hist-D. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Hist-D, from the product label.
Adaptogen Research
See all Adaptogen Research products- Name
- Adaptogen Research
- Street Address
- 625 Barksdale Road, Suite 113
- City
- Newark
- State
- DE
- ZipCode
- 19711
- Web Address
- adaptogenresearch.com
Hist-D by Adaptogen Research: Common Questions
Does Hist-D by Adaptogen Research interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hist-D is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
Hist-D's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC