Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Hunger Chews Mandarin Orange Ingredients & Drug Interactions

by Re-Body

Hunger Chews Mandarin Orange label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hunger Chews Mandarin Orange against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hunger Chews Mandarin Orange is a dietary supplement by Re-Body with 2 active ingredients. Its ingredients are commonly taken for depression and low mood, anxiety, pms symptoms.Based on those ingredients, 521 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Satiereal(R) Saffron Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hunger Chews Mandarin Orange by Re-Body

Ask about any prescription or over-the-counter medication and we check it for interactions with Hunger Chews Mandarin Orange by Re-Body — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hunger Chews Mandarin Orange by Re-Body

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Re-Body Hunger Chews Mandarin Orange contains one active ingredient: Satiereal(R) Saffron Extract. Saffron is a spice derived from the crocus flower, traditionally used in cooking and, in supplement form, studied for its effects on mood, cognition, and appetite.

The product also contains inactive ingredients (excipients) including cane syrup, brown rice syrup, natural flavors, rice syrup solids, palm oil, soy lecithin, citric acid, malic acid, glycerin, and color.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: helps control hunger and curb cravings.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence we hold shows that Satiereal(R) Saffron Extract is possibly effective for chemotherapy-induced peripheral neuropathy (nerve pain and numbness caused by cancer treatment) and possibly effective for Alzheimer disease. For appetite suppression or weight management—the implied use of a 'hunger chew'—the effectiveness data on file does not address those claims, so we cannot speak to how well this product works for that purpose based on the information we hold.

The evidence, ingredient by ingredient Saffron

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, saffron extract is generally well tolerated. The most common side effects are gastrointestinal complaints, nausea, sedation, and vomiting.

In rare cases, anaphylaxis (a severe allergic reaction) can occur, and allergy to saffron has been reported in trials; occupational exposure to saffron can trigger asthma and eye and nasal inflammation in sensitive people. At higher doses, saffron has occasionally caused anxiety and agitation in clinical trials.

Saffron should not be used in medicinal or supplement amounts during pregnancy, as it may stimulate the uterus. Data on breastfeeding is not on file, so talk with your doctor or pharmacist before using this product if you are nursing.

Side effects, ingredient by ingredient Saffron

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Saffron.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 521 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take CNS depressants (sedatives, sleep aids, opioids, or anti-anxiety drugs), blood pressure medications, diabetes medications, or use caffeine regularly. Saffron has documented moderate interactions with all of these drug types, and combining them could affect how well your medications work or increase side effects like drowsiness or low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with nerve pain from chemotherapy or support cognitive function in Alzheimer disease, though the evidence is not conclusive. If you take sleep aids, sedatives, blood pressure medications, diabetes medications, or caffeine regularly, you'll want to check with your doctor or pharmacist before starting it—saffron can interact with all of these.

It's not for use during pregnancy. A conversation with your own healthcare provider will help you decide if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hunger Chews Mandarin Orange, straight from the product label.

Brand Re-Body
Net contents 30 Soft Chew(s)
Market status On market
Date entered into DSLD Mar 25, 2013
DSLD ID 17985
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hunger Chews Mandarin Orange by Re-Body, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chew(s)
Maximum serving Sizes:
1 Chew(s)
Servings per container
30
IngredientAmount% DV
Calories20 {Calories}--
Total Carbohydrates4 g1%
Sugar3 g--
Satiereal(R) Saffron Extract88.5 mg--

Other ingredients: Cane syrup, Brown Rice syrup, Natural flavors, Rice syrup solids, Palm Oil, Soy Lecithin, Citric Acid, Malic Acid, Glycerin, Color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

-Helps control hunger and overeating* -Helps curb snack cravings*

1 855 4RE-BODY (473-2639)

APPETITE CONTROL FORMULA*

NATURALLY FLAVORED FRUIT CHEWS

Keep Re-Body Hunger Chews on hand to help curb those cravings throughout the day.*

Combined with a healthy diet and moderate exercise, Re_Body's Hunger Chews are a delicious supplement that helps support weight management.*

Help control your cravings, help control your weight-with every mouth-watering chew.

Precautions

DO NOT USE IF SEAL IS BROKEN.

Check with your healthcare practitioner before taking this product if you are pregnant, nursing, under a doctor's care or taking medication. Do not take this product if you are currently on anti-depressant medication.

Prior to beginning any exercise or diet program, you should consult your healthcare professional.

KEEP TIGHTLY CLOSED AND OUT OF REACH OF CHILDREN AND PETS.

Brand IP Statement(s)

Satiereal(R) is a trademark of INOREAL. International patents pending.

RE-BODY(R) SAFFRON HUNGER CHEWS(TM) APPETITE CONTROL FORMULA* WITH SATIEREAL(R) SAFFRON EXTRACT

Re-Body Hunger Chews(TM) contains clinically tested Satiereal(R) to help control hunger and reduce the intake of excess calories.

Seals/Symbols

Satiereal(R)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

0G FAT PER SERVING

Formula

20 CALORIES PER SERVING

-Active ingredient Satiereal(R) Saffron Extract 88.5 mg

88.5mg SATIEREAL(R) PER SERVING

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Use in conjunction with a reduced-calorie diet and exercise program.

Directions: As a dietary supplement, take 1 chew twice daily before meals.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hunger Chews Mandarin Orange by Re-Body label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hunger Chews Mandarin Orange label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hunger Chews Mandarin Orange by Re-Body

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Chew(s) Dosage formOther (e.g. Tea Bag) Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

3 g per serving

Satiereal(R) Saffron Extract

Interacts with
521 drugs
88.5 mg per serving

Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research us...

Satiereal(R) Saffron Extract monograph & interactions

Other (inactive) ingredients: Cane syrup, Brown Rice syrup, Natural flavors, Rice syrup solids, Palm Oil, Soy Lecithin, Citric Acid, Malic Acid, Glycerin, Color. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hunger Chews Mandarin Orange by Re-Body Drug Interactions

Want to check YOUR meds against Hunger Chews Mandarin Orange?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
521Drugs
521 Moderate

Ingredients driving the most interactions

Satiereal(R) Saffron Extract 521

Individual Drug Interactions

The ingredients in Hunger Chews Mandarin Orange interact with 521 drugs. Click any drug to see the details.

1 of the 2 ingredients in Hunger Chews Mandarin Orange interact with drugs. Each result below shows which ingredient is responsible. Satiereal(R) Saffron Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Hunger Chews Mandarin Orange with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Satiereal(R) Saffron Extract4 drug types · 521 drugs

Antidiabetes Drugs

Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.

Likelihood Possible Evidence D
Caffeine

Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.

Likelihood Possible Evidence D
Satiereal(R) Saffron Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hunger Chews Mandarin Orange, from the product label.

Re-Body

See all Re-Body products
Name
Re-Body, LLC
Street Address
700 South Florida Avenue, Suite 512
City
Tampa
State
Florida
ZipCode
33602
Phone Number
1 855 473-2639
Pharmacist Counseling Corner

Hunger Chews Mandarin Orange by Re-Body: Common Questions

Does Hunger Chews Mandarin Orange by Re-Body interact with any medications?
Yes. Based on its ingredients, Hunger Chews Mandarin Orange has a known interaction with 521 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hunger Chews Mandarin Orange contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No. Saffron in medicinal or supplement amounts is rated likely unsafe in pregnancy because it may stimulate the uterus. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before using this product.
Will this make me sleepy?
Yes, saffron extract can cause drowsiness and sedation, especially at the doses studied. If you notice sedation, be cautious with activities like driving, and talk with your pharmacist about whether this product is a good fit for you.
What is Satiereal(R) Saffron Extract?
Satiereal(R) is a branded form of saffron extract, the concentrated active compound from the saffron crocus flower. In studies, it has shown promise for nerve pain from chemotherapy and cognitive support in Alzheimer disease.
Is saffron safe at any dose?
Saffron is likely safe in the small amounts used to flavor food, but supplement doses should be used carefully—high doses can be toxic. The data we hold advises caution and careful dosing with supplements.
What are the most common side effects?
Stomach upset, nausea, sedation, and vomiting are the most commonly reported side effects. Rarely, allergic reactions including anaphylaxis can occur in people who are sensitive to saffron.
Can I take this with my caffeine?
Saffron may slow how your body clears caffeine, potentially raising caffeine levels. A small study found this effect in men but not women. If you drink coffee or take caffeine regularly, mention this product to your pharmacist before starting it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hunger Chews Mandarin Orange label
Go deeper

The Full Monographs Behind Hunger Chews Mandarin Orange’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Saffron

Interacts with 521 drugs

Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research uses small trials, so results are not defi...

Read the full Saffron monograph →
Sources

Sources & How We Checked

Hunger Chews Mandarin Orange's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Saffron 22 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Feo F, Martinez J, Martinez A, et al. Occupational allergy in saffron workers. Allergy 1997;52:633-41. PubMed
  5. Wuthrich B, Schmid-Grendelmeyer P, Lundberg M. Anaphylaxis to saffron. Allergy 1997;52:476-7. PubMed
  6. Akhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. Phytother Res 2005;19:148-51.
  7. Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasth
  8. Fatehi, M., Rashidabady, T., and Fatehi-Hassanabad, Z. Effects of Crocus sativus petals' extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig ileum. J Ethnopharmacol. 2003; PubMed
  9. Modaghegh, M. H., Shahabian, M., Esmaeili, H. A., Rajbai, O., and Hosseinzadeh, H. Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers. Phytomedicine. 2008;15(12):1032-1037. PubMed
  10. Imenshahidi, M., Hosseinzadeh, H., and Javadpour, Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats. Phytother.Res 12-9-2009;
  11. Zhang, Y., Shoyama, Y., Sugiura, M., and Saito, H. Effects of Crocus sativus L. on the ethanol-induced impairment of passive avoidance performances in mice. Biol.Pharm Bull. 1994;17(2):217-221. PubMed
  12. Wuthrich, B., Schmid-Grendelmeyer, P., and Lundberg, M. Anaphylaxis to saffron. Allergy 1997;52(4):476-477. PubMed
  13. Akhondzadeh S, Sabet MS, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SSh, Yousefi MH, Alimardani R, Jamshidi A, Zare F, Moradi A. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and plac
  14. Kashani L, Eslatmanesh S, Saedi N, Niroomand N, Ebrahimi M, Hosseinian M, Foroughifar T, Salimi S, Akhondzadeh S. Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial. Ph PubMed
  15. Kianbakht S, Ghazavi A. Immunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trial. Phytother Res. 2011 Dec;25(12):1801-5. PubMed
  16. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. J C
  17. Safarinejad MR, Shafiei N, Safarinejad S. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment. Int J Impo PubMed
  18. Talaei A, Hassanpour Moghadam M, Sajadi Tabassi SA, Mohajeri SA. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: a randomized, double-blind, placebo-controlled, pilot clinical trial. J Affect Disord. 2 PubMed
  19. Azimi P, Ghiasvand R Feizi A, Hariri M, Abbasi B. Effects of cinnamon, cardamom, saffron, and ginger consumption on markers of glycemic control, lipid profile, oxidative stress, and inflammation in type 2 diabetes. Rev Diabet Stud. 2014 Fall-Winter;11(3-4
  20. Begas E, Bounitsi M, Kilindris T, et al. Effects of short-term saffron (Crocus sativus L.) intake on the in vivo activities of xenobiotic metabolizing enzymes in healthy volunteers. Food Chem Toxicol. 2019;130:32-43. PubMed
  21. Moravej Aleali A, Amani R, Shahbazian H, Namjooyan F, Latifi SM, Cheraghian B. The effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabet
  22. Abbaszadeh-Mashkani S, Hoque SS, Banafshe HR, Ghaderi A. The effect of crocin (the main active saffron constituent) on the cognitive functions, craving, and withdrawal syndrome in opioid patients under methadone maintenance treatment. Phytother Res. 2021; PubMed

See these in context on the Saffron monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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