Hyal-Joint Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hyal-Joint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hyal-Joint is a dietary supplement by Doctor's Best with 2 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Hyal-Joint by Doctor's Best
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Hyal-Joint contains 2 active ingredients. Sodium hyaluronate is a form of hyaluronic acid, a substance that holds water in tissues and is used to support joint, skin, and eye health.
Collagen is a structural protein, though we don't have detailed information on file about how it works in this formula. The capsule also contains inactive ingredients: rice powder, gelatin, magnesium stearate (a binder), and silicon dioxide (an anti-caking agent).
Does it work?
Not established
Sodium hyaluronate has possibly effective evidence for dry eye and venous leg ulcers (slow-healing wounds on the lower leg). For aging skin, hay fever, and sexual dysfunction, the evidence isn't strong enough to rate it one way or the other — there's insufficient reliable data.
We don't have effectiveness information on file for collagen in this product.
How safe is it?
Well-documented data
Sodium hyaluronate (hyaluronic acid) appears to be well tolerated when taken by mouth or applied to skin. The safety notes on file advise caution because long-term safety of oral supplements isn't fully studied, and they recommend checking with your doctor before taking it orally.
Topical use has rarely caused eczema, redness, itching, or wound infection, and eye drops with hyaluronic acid have rarely caused eye pain. Pregnancy and lactation data for these ingredients isn't on file.
Talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for the sodium hyaluronate in this product. However, because collagen's interaction data is not on file with us, check with your doctor or pharmacist about whether it's appropriate for any medications you take.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
Hyal-Joint may be worth considering if you're interested in joint, skin, or eye support and your doctor agrees. Because we have no interaction data for collagen and the long-term safety of oral hyaluronic acid isn't fully established, it's worth a conversation with your own doctor or pharmacist before you start — especially if you take medications or are pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hyal-Joint, straight from the product label.
| Brand | Doctor's Best |
|---|---|
| Barcode (UPC) | 753950001947 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 22, 2016 |
| DSLD ID | 60197 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hyal-Joint by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Collagen | 2 mg | -- |
| Sodium Hyaluronate | 24 mg | -- |
| Hyal-Joint | 40 mg | -- |
Other ingredients: Rice powder, Gelatin Capsule, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Hyal-Joint is a patented extract of rooster combs composed of 60% hyaluronic acid, along with collagen and other glycosaminoglycans that form the structural components of connective tissue in joints.
General Statements
Essential for healthy joint function and mobility, hyaluronic acid occurs naturally in the body as a part of synovial fluid, which provides the liquid layer that cushions and lubricates joints.*
Helps maintain joint mobility*
HELPS NOURISH JOINT FLUID FOR ~ FREE AND EASY MOVEMENT*
Scan for more info
20 mg
Suggested Adult Use: Take 2 capsules twice daily with or without food, for one or more months, followed by 1 capsule twice daily for one or more months, followed by a maintenance dose of 1 capsule daily, or as recommendedy by a nutritionally-informed physician.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Hyal-Joint is a registered trademark of Bioiberica, S.A.
Science-Based Nutrition
General
DRB194-1
FDA Statement of Identity
Dietary Supplement
Formulation
Non-GMO and Gluten Free
Storage
Store in a cool dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hyal-Joint by Doctor's Best label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hyal-Joint by Doctor's Best
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Hyal-Joint
- › Collagen
- › Sodium Hyaluronate
Other (inactive) ingredients: Rice powder, Gelatin Capsule, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Hyal-Joint by Doctor's Best Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Hyal-Joint. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Hyal-Joint, from the product label.
Doctor's Best
See all Doctor's Best products- Name
- Doctor's Best, Inc.
- City
- San Clemente
- State
- CA
- ZipCode
- 92673
- Phone Number
- (800) 777-2474
- Web Address
- www.drbvitamins.com
Hyal-Joint by Doctor's Best: Common Questions
Does Hyal-Joint by Doctor's Best interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is sodium hyaluronate and what does it do in this supplement?
Is this safe to take long-term?
Can I take this if I'm pregnant or breastfeeding?
What does collagen do in this product?
Does this interact with medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hyal-Joint is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hyal-Joint’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hyal-Joint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hyaluronic Acid 4 references
- Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
- U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
- Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
- Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC