No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Hyaluronic Acid 50 mg Ingredients & Drug Interactions

by SimplySupplements

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Hyaluronic Acid 50 mg is a dietary supplement by SimplySupplements with 1 active ingredient. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Hyaluronic Acid 50 mg by SimplySupplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: hyaluronic acid at 50 mg per capsule. Hyaluronic acid is a naturally occurring compound found in connective tissue; oral supplements of it are marketed to support skin hydration, joint health, and eye moisture.

The capsule also contains inactive ingredients — maltodextrin, magnesium stearate, gelatin, and titanium dioxide — which are fillers, binders, and the capsule shell itself.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hyaluronic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: joint comfort and synovial fluid health.
  • We looked for evidence on: Osteoarthritis, Joint pain, Joint mobility, Cartilage support.
  • The closest evidence on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis (Natural Medicines).

The evidence for oral hyaluronic acid is mixed. It's rated possibly effective for dry eye and venous leg ulcers (slow-healing sores on the leg).

For aging skin, hay fever, and sexual dysfunction, there isn't enough reliable evidence in our data to rate its effectiveness — so we can't say whether it works or doesn't for those uses.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic acid taken by mouth or applied to skin appears to be well tolerated overall. The most common topical side effects are eczema, redness, itching, and rarely wound bleeding or infection.

One rare report mentions eye pain in people using eye drops with hyaluronic acid. The safety notes we hold flag that long-term safety of oral supplements isn't fully studied, and recommend talking with your doctor before taking oral hyaluronic acid supplements.

We don't have specific pregnancy or lactation safety data on file for this ingredient, so check with your own doctor or pharmacist if you're pregnant, breastfeeding, or planning to become pregnant.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That doesn't mean interactions can't occur — it means we hold no monograph data showing them.

Check with your own pharmacist or doctor before starting if you take any medications regularly.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Hyaluronic Acid 50 mg may be worth considering if you're interested in support for dry eyes or leg ulcers — though the evidence is modest. Long-term safety data is limited, so it's not a "set it and forget it" choice.

Talk it over with your own doctor or pharmacist before you start, especially if you're pregnant, breastfeeding, or taking any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hyaluronic Acid 50 mg, straight from the product label.

Brand SimplySupplements
Barcode (UPC) 5060208411188
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 22504
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hyaluronic Acid 50 mg by SimplySupplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
UPC/BARCODE
5060208411188
IngredientAmount% DV
Hyaluronic Acid50 mg--

Other ingredients: Maltodextrin, Magnesium Stearate, Gelatin, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

SimplySupplements(TM)

General Statements

HIGH STRENGTH

The Perfect Partner To Glucosamine

Quality Assured

Product Information The viscosity and elasticity of the synovial fluid within a joint is thought to rely upon a healthy supply of hyaluronic acid. This key component within synovial fluid has been widely referred to as the ‘goo’ molecule.

Image is for illustration purposes only.

AUTO DESPATCH SAVE 10% and get FREE P&P on all repeat orders by having your favourite supplements conveniently scheduled and delivered automatically with our unique Auto Despatch system. SAME DAY DESPATCH We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class! PRICE MATCH GUARANTEE! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!

Precautions

Food supplement: This product should not be used as a substitute for a varied diet.

Do not use if seal is broken.

Pregnant or lactating women should consult a Doctor before using this product.

Important Information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.

Do not exceed stated dose.

Keep away from children at all times.

Allergy Advice: Contains an ingredient derived from Beef.

Suggested/Recommended/Usage/Directions

Suggested Daily Intake Take one to four capsules daily as a food supplement or as directed by a healthcare professional.

Storage

Store in a cool dry place.

General

S752

See for yourself

Hyaluronic Acid 50 mg by SimplySupplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hyaluronic Acid 50 mg by SimplySupplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Hyaluronic Acid

No known
interactions
50 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Other (inactive) ingredients: Maltodextrin, Magnesium Stearate, Gelatin, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hyaluronic Acid 50 mg by SimplySupplements Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Hyaluronic Acid 50 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Hyaluronic Acid 50 mg, from the product label.

SimplySupplements

See all SimplySupplements products
Name
Simply Supplements
Street Address
PO Box 204
City
Guernsey
ZipCode
GY1 3NB
Pharmacist Counseling Corner

Hyaluronic Acid 50 mg by SimplySupplements: Common Questions

Does Hyaluronic Acid 50 mg by SimplySupplements interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Hyaluronic Acid 50 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Hyaluronic Acid 50 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does hyaluronic acid actually help dry eyes?
It's rated possibly effective for dry eye, which means there's some evidence it may help, but the research isn't conclusive yet. If you're considering it for that reason, ask your eye doctor whether it makes sense for your specific situation.
What are the side effects?
When taken by mouth or applied to skin, hyaluronic acid is generally well tolerated. Topical use has occasionally caused eczema, redness, itching, or (rarely) wound bleeding or infection. Eye drops containing it have rarely caused eye pain.
Is it safe to take long-term?
The long-term safety of oral hyaluronic acid supplements isn't fully studied yet. That's worth keeping in mind if you're thinking about taking it for months or years — talk with your doctor about whether it's right for you.
Can I take this if I'm pregnant or breastfeeding?
We don't have specific safety data on file for oral hyaluronic acid in pregnancy or lactation. That's a conversation to have with your own doctor or pharmacist — they can weigh what you need against what we know and don't know.
Will this help my skin look younger?
For aging skin, there isn't enough reliable evidence to say whether it works or doesn't. If that's what you're hoping it'll do, you might not find the science backs it up yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hyaluronic Acid 50 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hyaluronic Acid 50 mg label
Go deeper

The Full Monographs Behind Hyaluronic Acid 50 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Hyaluronic Acid 50 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring