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Dietary supplement

Pumpkin Seed 2000 mg Ingredients & Drug Interactions

by SimplySupplements

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pumpkin Seed 2000 mg is a dietary supplement by SimplySupplements with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pumpkin Seed 2000 mg by SimplySupplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: pumpkin seed at 2000 mg per capsule. The inactive ingredients are maltodextrin, gelatin, and magnesium stearate — common binders and capsule material used to hold the supplement together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: prostate health and prevention.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Overactive bladder, Prostate function, Urinary health.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Overactive bladder.

Pumpkin seed is possibly effective for benign prostatic hyperplasia (BPH), a condition where the prostate gland enlarges and can make urination difficult. For other uses — including male-pattern hair loss, interstitial cystitis (bladder pain), intestinal parasite infection, and urinary tract infections — the evidence isn't strong enough yet to rate it.

We don't have established effectiveness data for those conditions.

The evidence, ingredient by ingredient Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin as a food is well tolerated, but concentrated seed supplements are less well studied. The most common side effects from oral pumpkin products are abdominal discomfort, diarrhea, nausea, and vomiting.

Rarely, anaphylaxis (a severe allergic reaction) has been reported. There are also two case reports of temporary hair loss linked to bitter-tasting pumpkin or squash with high levels of a plant compound called cucurbitacin — thought to be from wild varieties.

For pregnancy and breastfeeding, the data on concentrated pumpkin seed supplements isn't robust enough to say whether they're safe; talk with your doctor or pharmacist about whether to use this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium (a mood stabilizer), check with your doctor or pharmacist before using this product — pumpkin seed might raise lithium levels in your blood and require a dose adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pumpkin seed may be worth trying if you have benign prostate enlargement and want a natural option. If you take lithium, check with your doctor or pharmacist before adding this — your dose might need adjusting.

For other uses, the evidence is too thin to say it'll help. Have your medications reviewed before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pumpkin Seed 2000 mg, straight from the product label.

Brand SimplySupplements
Barcode (UPC) 5060208416701
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 22431
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pumpkin Seed 2000 mg by SimplySupplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
5060208416701
IngredientAmount% DV
Pumpkin200 mg--

Other ingredients: Maltodextrin, Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

HIGH STRENGTH

Packed with high levels of zinc magnesium, calcium, iron and vitamins.

Image is for illustration purposes only.

- Easy to Swallow - Easy to Absorb - Easy to Digest - No Product Odour - No Bad Taste

AutoDespatch SAVE 10% and get FREE P&P on all repeat orders by having your favourite supplements conveniently scheduled and delivered automatically with our unique Auto Despatch system. Same Day Despatch We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class! Price Match Guarantee! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!

Quality Assured

Formula

Product Information A supplement exclusively for men which may help prostate health and act as a prevention remedy for the future.

An Important supplement for men

Precautions

Important Information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.

Do not exceed stated dose.

Keep away from children at all times.

Do not use if seal is broken.

Pregnant or lactating women should consult a Doctor before using this product.

Allergy Advice: Contains gelatin which is derived from Beef.

Food supplement: This product should not be used as a substitute for a varied diet.

Seals/Symbols

EasyGest CAPSULES

SimplySupplements(TM)

General

S622

Suggested/Recommended/Usage/Directions

Suggested Daily Intake Take one capsule daily as a food supplement or as directed by a healthcare professional

Storage

Store in a cool dry place.

See for yourself

Pumpkin Seed 2000 mg by SimplySupplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pumpkin Seed 2000 mg by SimplySupplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Pumpkin

Interacts with
1 drug
200 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin monograph & interactions

Other (inactive) ingredients: Maltodextrin, Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pumpkin Seed 2000 mg by SimplySupplements Drug Interactions

Want to check YOUR meds against Pumpkin Seed 2000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pumpkin Seed 2000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pumpkin1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Pumpkin Seed 2000 mg, from the product label.

SimplySupplements

See all SimplySupplements products
Phone Number
0800 988 0292
Pharmacist Counseling Corner

Pumpkin Seed 2000 mg by SimplySupplements: Common Questions

Does Pumpkin Seed 2000 mg by SimplySupplements interact with any medications?
Yes. Based on its ingredients, Pumpkin Seed 2000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pumpkin Seed 2000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pumpkin seed used for?
Pumpkin seed is possibly effective for benign prostatic hyperplasia (BPH), a condition where the prostate gland enlarges and affects urination. For other uses — like male-pattern hair loss, urinary tract infections, and bladder pain — the evidence isn't established yet in our data.
Does pumpkin seed have side effects?
Most people tolerate it well. The common side effects are mild: abdominal discomfort, diarrhea, nausea, and vomiting. Rarely, anaphylaxis (a serious allergic reaction) has been reported. There are also two case reports of temporary hair loss tied to bitter-tasting pumpkin with high levels of a plant toxin, likely from wild varieties.
Is it safe to take during pregnancy or breastfeeding?
The data on concentrated pumpkin seed supplements during pregnancy and breastfeeding isn't thorough enough to know either way. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or nursing.
What's actually in this product?
It's one active ingredient — 2000 mg of pumpkin seed — plus inactive fillers: maltodextrin, gelatin, and magnesium stearate, which help hold the capsule together.
Will it interact with my blood pressure or thyroid medication?
No interactions are documented in our data for those drug types. The one documented interaction is with lithium. Use the search tool on this page to check your exact medications before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pumpkin Seed 2000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pumpkin Seed 2000 mg label
Go deeper

The Full Monographs Behind Pumpkin Seed 2000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pumpkin Seed 2000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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