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Dietary supplement

Pumpkin Seed Oil 2000 mg Ingredients & Drug Interactions

by Vitamatic

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pumpkin Seed Oil 2000 mg is a dietary supplement by Vitamatic with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pumpkin Seed Oil 2000 mg by Vitamatic

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains three ingredients: pumpkin seed oil (the active component at 2000 mg per serving) and two types of dietary fat — polyunsaturated and monounsaturated. The softgel capsule itself is an inactive ingredient that holds everything together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cardiovascular health and prostate function support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Overactive bladder, prostate health, urinary function.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Overactive bladder.

The evidence behind pumpkin seed oil is limited. It's possibly effective for benign prostatic hyperplasia (BPH) — a condition where an enlarged prostate causes urinary symptoms.

For everything else listed — hair loss, bladder inflammation (interstitial cystitis), parasite infections, and urinary tract infections — the evidence isn't reliable enough to rate it either way.

The evidence, ingredient by ingredient Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin as a food is well tolerated. The concentrated seed-oil supplements in this product are generally well tolerated too, though the long-term safety data on supplements isn't as robust as it is for whole food.

The most common side effects in trials are abdominal discomfort, diarrhea, nausea, and vomiting. Anaphylaxis (a severe allergic reaction) is very rare.

Two case reports describe temporary hair loss a few weeks after eating pumpkin or squash with high levels of cucurbitacin (a bitter compound); this is uncommon and was tied to wild or bitter-tasting varieties. There isn't enough data to say whether this concentrated supplement is safe during pregnancy or breastfeeding.

Talk with your doctor or pharmacist about whether it's right for you in these situations.

Side effects, ingredient by ingredient Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, flag this product with your doctor or pharmacist before you start — pumpkin seed oil may reduce lithium excretion and raise its levels in your body, and your dose may need adjustment. No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pumpkin seed oil may help with an enlarged prostate (BPH), though the evidence is still developing. If you take lithium, you need to check with your doctor or pharmacist before starting — the product might affect your lithium levels.

Otherwise, it's generally well tolerated, but run any medications you're on through the interaction checker on this page first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pumpkin Seed Oil 2000 mg, straight from the product label.

Brand Vitamatic
Barcode (UPC) 602343800721
Net contents 180 Softgel(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 283075
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pumpkin Seed Oil 2000 mg by Vitamatic, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
90
UPC/BARCODE
602343800721
IngredientAmount% DV
Calories20 Calorie(s)--
Polyunsaturated Fat1 Gram(s)--
Monounsaturated Fat0.5 Gram(s)--
Total Fat2 Gram(s)3%
Saturated Fat0.5 Gram(s)3%
Pumpkin seed Oil2 Gram(s)--

Other ingredients: Softgel Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports: Cardiovascular health Extra virgin, cold pressed Rich in phytosterols

Free of sugar, starch, sodium, yeast, soy, corn, wheat, egg, artificial colors, flavors & preservatives.

Supports healthy prostate function Contains essential fatty acids Cold pressed

Non GMO

Precautions

Caution: Consult with your healthcare provider if you are pregnant, nursing, taking any medications or planning any medical procedures.

Do not use it if the safety seal is broken or missing.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice Certified Made in U.S.A.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults: As a dietary supplement, take two (2) softgels daily preferably before meal.

See for yourself

Pumpkin Seed Oil 2000 mg by Vitamatic label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pumpkin Seed Oil 2000 mg by Vitamatic

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.

Pumpkin seed Oil

Interacts with
1 drug
2 Gram(s) per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin seed Oil monograph & interactions

Other (inactive) ingredients: Softgel Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pumpkin Seed Oil 2000 mg by Vitamatic Drug Interactions

Want to check YOUR meds against Pumpkin Seed Oil 2000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pumpkin Seed Oil 2000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pumpkin seed Oil1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Pumpkin Seed Oil 2000 mg, from the product label.

Vitamatic

See all Vitamatic products
Name
Vitamatic
Street Address
PO Box 406
City
Raritan
State
NJ
ZipCode
08869
Phone Number
1-973-400-9165
Web Address
www.vitamaticusa.com
Pharmacist Counseling Corner

Pumpkin Seed Oil 2000 mg by Vitamatic: Common Questions

Does Pumpkin Seed Oil 2000 mg by Vitamatic interact with any medications?
Yes. Based on its ingredients, Pumpkin Seed Oil 2000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pumpkin Seed Oil 2000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does pumpkin seed oil actually help with prostate problems?
It's possibly effective for benign prostatic hyperplasia (BPH), the condition that causes an enlarged prostate and urinary trouble. That means there's some evidence, but not a lot — more research is needed. Talk with your doctor about whether it makes sense for your situation.
What are the most common side effects?
Most people tolerate it fine. A small number of trial participants reported abdominal discomfort, diarrhea, nausea, or vomiting. Severe allergic reactions are very rare.
Can I take this while pregnant or breastfeeding?
There isn't enough data to know whether concentrated pumpkin seed oil supplements are safe in pregnancy or breastfeeding. Pumpkin as a food is fine, but the supplement is a different story. Talk with your doctor or pharmacist — they can help you decide whether it's right for you.
What does this product actually contain?
The main ingredient is pumpkin seed oil (2000 mg per serving), plus polyunsaturated and monounsaturated fats. The softgel capsule is just the delivery method.
I've heard pumpkin can cause hair loss. Should I worry?
There are two old case reports of temporary hair loss a few weeks after eating pumpkin or squash with very high levels of a bitter compound called cucurbitacin — this is found mostly in wild pumpkins. It's very uncommon and hasn't been reported with standard pumpkin seed oil products. If you notice any unusual hair loss, mention it to your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pumpkin Seed Oil 2000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pumpkin Seed Oil 2000 mg label
Go deeper

The Full Monographs Behind Pumpkin Seed Oil 2000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pumpkin Seed Oil 2000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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