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Dietary supplement

Hydrangea Ingredients & Drug Interactions

by Herbalist & Alchemist

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Hydrangea is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for kidney and bladder stones, urinary tract complaints, enlarged prostate symptoms.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are dried Hydrangea root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Hydrangea by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dried hydrangea root extract. Hydrangea is thought to work as a diuretic, a substance that encourages urine output.

The liquid is suspended in distilled water, ethyl alcohol, and vegetable glycerin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: promotes healthy urinary tract function.
  • We looked for evidence on: Urinary tract infections, Kidney stones, Bladder health.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Our data hold no effectiveness ratings for hydrangea root extract against any specific condition. The evidence to support its use isn't established in the information we have on file.

The evidence, ingredient by ingredient Hydrangea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for hydrangea are limited, and large or prolonged doses may cause unwanted effects. Possible side effects from oral use include gastroenteritis (stomach and intestinal irritation), dizziness, and a feeling of tightness in the chest.

The safety data advise against use during pregnancy and while breastfeeding, as there isn't enough reliable information to ensure it's safe in these situations.

Side effects, ingredient by ingredient Hydrangea

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hydrangea.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, check with your pharmacist or doctor before starting this product. Hydrangea may reduce how your body clears lithium, potentially raising its level in your blood.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Hydrangea may be worth considering if you're interested in its traditional diuretic properties, but the evidence supporting it isn't established in our data. If you take lithium, you'll need to talk with your pharmacist or doctor before starting—your dose may need to change.

Because safety data are limited, especially at higher doses or longer term, it's a good idea to discuss this product with your pharmacist before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hydrangea, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056116743
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175826
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hydrangea by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
667056116743
IngredientAmount% DV
dried Hydrangea root extract2 mL--

Other ingredients: distilled Water, Ethyl Alcohol, Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Hydrangea arborescens

OK

General Statements

Promotes healthy urinary tract function

Botanical preparation ratio 1:4

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 20-40 drops (1-2 mL) in juice or water. Take 4 times per day. Shake well before using.

Precautions

Contraindications: Use with caution during pregnancy.

Keep out of children's reach

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General

NO. HYD-2 1740FR

Seals/Symbols

OK

See for yourself

Hydrangea by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Hydrangea by Herbalist & Alchemist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Dried Hydrangea root extract

Interacts with
1 drug
2 mL per serving

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to...

Dried Hydrangea root extract monograph & interactions

Other (inactive) ingredients: Distilled Water, Ethyl Alcohol, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hydrangea by Herbalist & Alchemist Drug Interactions

Want to check YOUR meds against Hydrangea?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Hydrangea with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

dried Hydrangea root extract1 drug type · 1 drug

Lithium

Hydrangea is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, hydrangea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Hydrangea, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

Hydrangea by Herbalist & Alchemist: Common Questions

Does Hydrangea by Herbalist & Alchemist interact with any medications?
Yes. Based on its ingredients, Hydrangea has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hydrangea contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is hydrangea used for?
Hydrangea root extract is traditionally thought to work as a diuretic, meaning it may encourage urine output. Our data don't establish its effectiveness for any specific condition, so talk with your pharmacist about whether it's right for you.
Can I take this while pregnant or breastfeeding?
The safety data advise against both. There isn't enough reliable information to know it's safe during pregnancy or while breastfeeding. Talk with your doctor or midwife for personalized advice.
What side effects might I experience?
Possible side effects include gastroenteritis (stomach and intestinal irritation), dizziness, and a feeling of tightness in the chest. Human safety data are limited, so larger or prolonged doses may cause unwanted effects we don't yet know about.
Is this product safe for long-term use?
Safety data are limited. Large or prolonged doses may cause unwanted effects, so it's best to talk with your pharmacist about how long you plan to use it and whether that's safe for you.
Does this contain any fillers or additives?
The liquid is formulated in distilled water, ethyl alcohol, and vegetable glycerin. These are inactive ingredients used to deliver and preserve the extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hydrangea is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hydrangea label
Sources

Sources & How We Checked

Hydrangea's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hydrangea 1 reference
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

See these in context on the Hydrangea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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