No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Illicium Supreme 450 mg Ingredients & Drug Interactions

by Supreme Nutrition Products

Illicium Supreme 450 mg label
See full label image
Capsule Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Illicium Supreme 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Illicium Supreme 450 mg is a dietary supplement by Supreme Nutrition Products with 1 active ingredient. Its ingredients are commonly taken for digestive upset and gas, cough and respiratory complaints, antimicrobial.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Illicium Supreme 450 mg by Supreme Nutrition Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Illicium Supreme contains one active ingredient: star anise (Illicium), supplied at 450 mg per capsule. The capsule itself is made from vegetable cellulose, an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Star Anise product and its label doesn't state a use — see Star Anise's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for star anise in our records, so we can't tell you what this supplement is intended to do or whether evidence supports its use.

The evidence, ingredient by ingredient Star Anise

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Star anise eaten in the small amounts you'd use in cooking is generally well tolerated. But this product is a concentrated supplement dose, and the safety of medicinal amounts isn't established.

Avoid it in supplement or tea form because of contamination risk and lack of safety data. Serious adverse effects from star anise tea are rare but documented: neurological effects like increased reflexes, jitteriness, rapid eye movements, seizures, and vomiting have been reported, though it's unclear whether contamination with toxic species played a role.

Gastrointestinal effects like vomiting, diarrhea, and abdominal distension have also been reported. Applied to skin, star anise can cause dermatitis (irritation, redness, scaling, and blistering).

Side effects, ingredient by ingredient Star Anise

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could check. Still, run your exact medications through the checker on this page before you start, and let your doctor or pharmacist know you're considering this product given the safety gaps.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Star anise in food amounts is generally safe, but this concentrated supplement raises concerns because medicinal safety isn't established and contamination with toxic look-alike species is a documented risk. If you're considering it, talk with your doctor or pharmacist first about whether the benefit is worth that uncertainty — and about your specific situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Illicium Supreme 450 mg, straight from the product label.

Brand Supreme Nutrition Products
Net contents 90 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Sep 24, 2021
DSLD ID 252068
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Illicium Supreme 450 mg by Supreme Nutrition Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Illicium450 mg--

Other ingredients: Vegetable Cellulose Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule twice daiy or as directed by a physician.

Precautions

If pregnant or breastfeeding consult your physician before using this product.

Keep out of reach of children.

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to treat, diagnose, prevent or cure any disease or illness.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Illicium Supreme 450 mg by Supreme Nutrition Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Illicium Supreme 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Illicium Supreme 450 mg by Supreme Nutrition Products

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Illicium

No known
interactions
450 mg per serving

Star anise (Illicium verum) is a star-shaped spice widely used in cooking and traditional medicine, mostly for digestive and respiratory complaints. H...

Illicium monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Illicium Supreme 450 mg by Supreme Nutrition Products Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Illicium Supreme 450 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Illicium Supreme 450 mg, from the product label.

Supreme Nutrition Products

See all Supreme Nutrition Products products
Name
Supreme Nutrition Products
Street Address
1019 Regents Blvd #203
City
Tacoma
State
WA
ZipCode
98466
Web Address
www.SupremeNutritionProducts.com
Pharmacist Counseling Corner

Illicium Supreme 450 mg by Supreme Nutrition Products: Common Questions

Does Illicium Supreme 450 mg by Supreme Nutrition Products interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Illicium Supreme 450 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Illicium Supreme 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is star anise safe to take as a supplement?
The safety data for concentrated supplements isn't established. Food amounts are generally well tolerated, but medicinal doses and supplement forms carry contamination risk — toxic look-alike species have appeared in some batches — and lack solid safety data. Talk with your doctor or pharmacist before starting.
What are the serious side effects of star anise?
They're rare, but star anise tea has been linked to neurological effects like seizures, rapid eye movements, jitteriness, and vomiting — though it's unclear if contamination with a toxic species was involved. Gastrointestinal effects like vomiting, diarrhea, and belly distension have also been reported. If applied to skin, it can cause dermatitis (irritation and redness).
Is it safe to take during pregnancy or while breastfeeding?
The safety data we hold shows conflicting ratings — one entry marks star anise as likely safe in pregnancy and lactation, while another marks it possibly unsafe. Because the evidence is mixed and safety for concentrated supplements isn't established, talk with your doctor or pharmacist for personalized advice before taking it.
What is star anise used for?
We don't hold effectiveness data for this product, so we can't tell you what it's intended to treat or whether evidence supports its use. Your doctor or pharmacist can discuss that with you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Illicium Supreme 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Illicium Supreme 450 mg label
Go deeper

The Full Monographs Behind Illicium Supreme 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Star Anise

Star anise (Illicium verum) is a star-shaped spice widely used in cooking and traditional medicine, mostly for digestive and respiratory complaints. Human evidence for health benefits is lim...

Read the full Star Anise monograph →
Sources

Sources & How We Checked

Illicium Supreme 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Star Anise 10 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Anon. FDA issue advisory on star anise "teas." FDA News P03-67; September 10, 2003.
  3. Ize-Ludlow D, Ragone S, Bernstein JN, et al. Chemical composition of Chinese star anise (Illicium verum) and neurotoxicity in infants. JAMA 2004;291:562-3. PubMed
  4. Ize-Ludlow D, Ragone S, Bruck IS, et al. Neurotoxicities in infants seen with the consumption of star anise tea. Pediatrics 2004;114:e653-6. PubMed
  5. Franks A. Contact allergy to anethole in toothpaste associated with loss of taste. Contact Dermatitis 1998;38:354-5. PubMed
  6. Rudzki E, Grzywa Z. Sensitizing and irritating properties of star anise oil. Contact Dermatitis 1976;2:305-8. PubMed
  7. Garzo, Fernandez C., Gomez, Pintado P., Barrasa, Blanco A., Martinez, Arrieta R., Ramirez, Fernandez R., and Ramon, Rosa F. [Cases of neurological symptoms associated with star anise consumption used as a carminative]. An.Esp.Pediatr. 2002;57(4):290-294.
  8. Minodier, P., Pommier, P., Moulene, E., Retornaz, K., Prost, N., and Deharo, L. [Star anise poisoning in infants]. Arch Pediatr. 2003;10(7):619-621.
  9. Casanova Cuenca M, Calzado Agrasot MÁ, Mir Pegueroles C, Esteban Cantó V. New cases of star anise poisoning: Are we providing enough information? Neurologia. 2019;34(3):211-213. DOI
  10. Donner J, Ruest S. Neonate with seizures after consuming star anise tea. R I Med J. 2021 Oct 1;104(8):8-10.

See these in context on the Star Anise monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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