Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Immune FX Ingredients & Drug Interactions

by The People's Chemist

Immune FX label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Immune FX against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Immune FX is a dietary supplement by The People's Chemist with 2 active ingredients. Its ingredients are commonly taken for common cold and flu symptoms, upper respiratory infections, sore throat.Based on those ingredients, 912 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are full spectrum Coriandrum sativum, full spectrum Andrographis paniculata. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Immune FX by The People's Chemist

Ask about any prescription or over-the-counter medication and we check it for interactions with Immune FX by The People's Chemist — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Immune FX by The People's Chemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Immune FX Blend” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

Immune FX contains 2 active ingredients: full spectrum andrographis (Andrographis paniculata) and full spectrum coriander (Coriandrum sativum). These are plant extracts—andrographis is traditionally used for inflammation and immune support, while coriander is a culinary spice sometimes used for digestive and metabolic purposes.

The product is delivered in gelatin capsules.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Nature's immunity booster for flu, colds, infections.
  • We looked for evidence on: Influenza, Upper respiratory tract infection (URTI), Tonsillopharyngitis, Acute bronchitis, Rhinosinusitis, Skin irritation — and 4 related terms.
  • The strongest evidence on file: Andrographis is rated "Possibly Effective" for Tonsillopharyngitis (Natural Medicines).
  • Also on file: Coriander is rated "Insufficient Reliable Evidence To Rate" for Skin irritation.
  • Also on file: Andrographis is rated "Insufficient Reliable Evidence To Rate" for Acute bronchitis, Upper respiratory tract infection (URTI), Influenza, Rhinosinusitis, and more.

The evidence for this product is limited. Andrographis has "possibly effective" ratings for ulcerative colitis (inflammatory bowel disease), tonsillopharyngitis (sore throat or tonsil inflammation), and osteoarthritis, though the data aren't definitive.

Coriander has insufficient evidence to establish whether it works for any of the conditions it's been studied for—anorexia, anxiety, constipation, diabetes, diarrhea, and indigestion. The product is sold as an immune support formula, but we hold no effectiveness data specifically for that claim.

The evidence, ingredient by ingredient Andrographis Coriander

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Andrographis is generally well tolerated at normal doses over short periods, but the quality of products and long-term safety aren't well established. At higher doses (5–10 mg/kg of andrographolide content) or beyond 14 days, side effects become more likely: abdominal discomfort, altered taste, diarrhea, dizziness, fatigue, headache, nausea, vomiting, itching, and rash.

Rare but serious reactions—including severe allergic reactions and anaphylaxis—have been reported. Skin reactions are frequent enough to warrant attention; cases of Stevens-Johnson syndrome and other severe rashes have been documented.

Coriander is generally well tolerated orally and topically, though contact dermatitis can occur in sensitive people, and rare anaphylaxis has been reported. The safety data advises against andrographis during pregnancy because of theoretical and animal study concerns about reproductive effects.

There isn't enough safety information to recommend andrographis while breastfeeding. For coriander, the pregnancy and lactation safety data isn't on file.

Side effects, ingredient by ingredient Andrographis Coriander

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Coriander, Andrographis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 912 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, have your doctor or pharmacist review it if you take blood thinners or antiplatelet drugs (moderate risk of bleeding), blood pressure medications (moderate risk of low pressure), immunosuppressants (moderate risk of interference), sedatives or CNS depressants (moderate risk of added drowsiness), photosensitizing drugs (moderate risk of sun sensitivity), diabetes medications (moderate risk of low blood sugar), or the pain relievers etoricoxib or celecoxib, or the diabetes drug glipizide (minor interactions with unclear clinical importance).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in andrographis for a sore throat, inflammatory bowel condition, or joint pain, this product may be worth discussing with your doctor—the evidence is modest but present. However, if you take blood thinners, blood pressure medications, diabetes drugs, sedatives, or immunosuppressants, you'll need to check with your own doctor or pharmacist first, because the interactions are real and potentially significant.

Pregnant or breastfeeding individuals should avoid andrographis. Always confirm your specific medications against this product before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Immune FX, straight from the product label.

Brand The People's Chemist
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 240338
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Immune FX by The People's Chemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Immune FX Blend1000 mg--
full spectrum Andrographis paniculata600 mg--
full spectrum Coriandrum sativum400 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Nature's immunity booster

Raw

Organic

Gluten free Non GMO No soy No excipients

Frequently Asked Questions 1. What would I take Immune FX for? You can take Immune FX to treat flu, strep throat, pneumonia, the common cold and most any skin infection (along with appropriate topical ointments).

10. What is the difference between Relief FX, Joint FX and Immune FX? Relief FX is the most potent, non-toxic, natural pain killer available. It’s safe enough for children, yet strong enough for the NFL. Joint FX is a non-toxic, natural blend for those suffering from joint pain and stiffness. By helping the body rebuild cartilage, it relieves joint pain.

Immune FX helps the immune system overcome illness by helping to rid the body of “biological nasties.” It will not soothe pain and it should NOT be taken as a preventive measure. It is to be taken only when ill or suffering from allergies.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

2. How often do I take Immune FX? You can take it daily, unless you’re trying to become pregnant or are currently pregnant.

5. The usage on the bottle says to take 1-2 capsules twice daily to fight infection. So does that mean that along with everything else, now I have to take another supplement every day? No. You only need to take Immune FX when you are trying to fight off infection. It is not intended to be taken daily as a regular supplement. Generally, children would take the smaller dose and adults, the larger. 6. How will I know if I need to take more? As your body’s immune response kicks into a higher gear, you should start to feel better within a day or two. The natural ingredients in Immune FX can help to remove “biological nasties” from your body, so you spend less time feeling sick and more time living young. If you feel dehydrated or have a dry mouth, you took too much.

11. Since the usage does not specify, should I take Immune FX with food or on an empty stomach? Take after a meal. 12. Can I take it with alcohol? Yes. 13. When should I stop taking it? When you're better.

Precautions

3. Can I take Immune FX if I’m breastfeeding? Yes, it is 100% safe and effective for mom to take. Indirectly, this will help babies’ immune system, too.

4. Can I take it for allergies? Yes. Many people have found that their air-born allergies are much easier to manage with Immune FX. Unlike common medications, it helps remove biological nasties and works with the body’s own natural defenses, without suppressing other functions.

7. Can I take this if I am pregnant? No.

8. Is there anything else I should do in conjunction with taking Immune FX? Yes. There is a whole chapter dedicated to overcoming illness safely and naturally in the award-winning book, Over-The-Counter Natural Cures. You should buy it and read it. Be sure to apply everything laid out in that chapter. There are some simple, but powerful, steps to follow so you can avoid antibiotics.

9. Can I take Immune FX with medication? Yes.

14. Can I give Immune FX to my children? Yes. If they can swallow a pill. You can’t open the capsule and put into food or drink because the active ingredients taste horrible. It might be possible to conceal taste in yogurt and maple syrup…But it’s a long shot.

General Statements

For more information on how to prevent illness, live healthier & feel younger than you’ve ever felt in your life, buy and read, Over-The-Counter Natural Cures and The Stop Eating So F#@%ing Much Diet and follow all of the suggestions.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Immune FX by The People's Chemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Immune FX label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Immune FX by The People's Chemist

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Immune FX Blend

1000 mg per serving

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Immune FX by The People's Chemist Drug Interactions

Want to check YOUR meds against Immune FX?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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912Drugs
911 Moderate 1 Minor

Ingredients driving the most interactions

full spectrum Coriandrum sativum 717
full spectrum Andrographis paniculata 413

Individual Drug Interactions

The ingredients in Immune FX interact with 912 drugs. Click any drug to see the details.

2 of the 2 ingredients in Immune FX interact with drugs. Each result below shows which ingredient is responsible. full spectrum Coriandrum sativum full spectrum Andrographis paniculata

Each ingredient & the kinds of drugs it affects

For each ingredient in Immune FX with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

full spectrum Coriandrum sativum4 drug types · 717 drugs

Antidiabetes Drugs

Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.

Likelihood Possible Evidence D
full spectrum Coriandrum sativum full monograph & interactions

full spectrum Andrographis paniculata6 drug types · 413 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal and laboratory studies suggest that andrographis has antiplatelet effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that andrographis has hypotensive effects.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Laboratory research suggests that andrographolide has immunostimulant activity.

Likelihood Possible Evidence D
Celecoxib (Celebrex)

Theoretically, andrographis extract might increase the maximum concentration and time to peak concentration of celecoxib. The clinical significance of these changes is unclear.
Animal research suggests that andrographis extract taken orally increases the maximum concentration and time to peak concentration of celecoxib but does not appear to impact the area under the curve.

Likelihood Possible Evidence D
Etoricoxib (Arcoxia)

Theoretically, andrographis might decrease the absorption of etoricoxib, although the clinical significance is unclear.
Animal research shows that andrographis extract, or the constituent andrographolide, taken orally with etoricoxib decreases the bioavailability of etoricoxib. However, this reduced bioavailability is not correlated with a reduction in the anti-inflammatory effects of etoricoxib in arthritic mice models. The clinical significance of this interaction is unclear.

Likelihood Possible Evidence D
Glipizide (Glucotrol)

Theoretically, andrographis extract might increase the maximum concentration and area under the curve of glipizide; however, opposite effects are seen with the constituent, andrographolide. The clinical significance of this interaction is unclear.
Animal research suggests that andrographis extract taken orally with glipizide in diabetes-induced rats increases the maximum concentration and area under the curve of glipizide. However, the opposite effect is seen with the constituent, andrographolide, in which the maximum concentration and area under the curve are decreased when taken with glipizide.

Likelihood Possible Evidence D
full spectrum Andrographis paniculata full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Immune FX, from the product label.

The People's Chemist

See all The People's Chemist products
Name
The People's Chemist
Pharmacist Counseling Corner

Immune FX by The People's Chemist: Common Questions

Does Immune FX by The People's Chemist interact with any medications?
Yes. Based on its ingredients, Immune FX has a known interaction with 912 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Immune FX contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is andrographis safe to take long-term?
Andrographis is often well tolerated for short-term use, but long-term safety isn't well established. The research shows that doses stay gentler and side effects are less likely when you keep doses below 5–10 mg/kg of andrographolide and use it for 14 days or fewer. Talk with your doctor if you're thinking of taking it longer.
Can I take this if I'm pregnant or breastfeeding?
No—the safety data advises against andrographis during pregnancy due to theoretical and animal-study concerns about reproductive effects. There also isn't enough safety information to recommend it while breastfeeding. Coriander's pregnancy and lactation safety information isn't on file. Speak with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or nursing.
What side effects might I experience?
Common side effects of andrographis include stomach discomfort, changes in taste, diarrhea, dizziness, tiredness, headache, nausea, vomiting, itching, and rash. These happen more often at higher doses or beyond 14 days of use. Coriander is generally well tolerated orally, though itching and burning sensations can occur if applied to skin. Rare but serious allergic reactions, including anaphylaxis, have been reported with both ingredients.
Does coriander actually help with diabetes or digestion?
The evidence we hold on coriander for diabetes, indigestion, constipation, diarrhea, anorexia, and anxiety is insufficient—we can't confirm it works for any of these. Coriander is safe in normal food amounts, but medicinal doses lack solid safety data.
Why does this product interact with so many drugs?
Andrographis can lower blood pressure, may thin the blood slightly, and may stimulate the immune system—actions that overlap with how many common medications work. Coriander similarly affects blood pressure, blood sugar, and sedation. When a plant extract shares those same pathways with your drugs, there's potential for an additive or interfering effect. That's why checking your exact medications is important.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Immune FX label
Go deeper

The Full Monographs Behind Immune FX’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Andrographis

Interacts with 413 drugs

Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten how long they last. The evidence is limi...

Read the full Andrographis monograph → Herb & supplement monograph

Coriander

Interacts with 717 drugs

Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a food it is generally safe for most people,...

Read the full Coriander monograph →
Sources

Sources & How We Checked

Immune FX's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 38 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Andrographis 26 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Thamlikitkul V, Dechatiwongse T, Theerapong S, et al. Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults. J Med Assoc Thai 1991;74:437-42.
  3. Zhang CY, Tan BK. Mechanisms of cardiovascular activity of Andrographis paniculata in the anaesthetized rat. J Ethnopharmacol 1997;56:97-101. PubMed
  4. Zhao HY, Fang WY. Antithrombotic effects of Andrographis paniculata nees in preventing myocardial infarction. Chin Med J (Engl) 1991;104:770-5.
  5. Amroyan E, Gabrielian E, Panossian A, et al. Inhibitory effect of andrographolide from Andrographis paniculata on PAF-induced platelet aggregation. Phytomedicine 1999;6:27-31. PubMed
  6. Zhang C, Kuroyangi M, Tan BK. Cardiovascular activity of 14-deoxy-11,12-didehydroandrographolide in the anaesthetised rat and isolated right atria. Pharmacol Res 1998;38:413-7. PubMed
  7. Puri A, Saxena R, Saxena RP, et al. Immunostimulant agents from Andrographis paniculata. J Nat Prod 1993;56:995-9. PubMed
  8. Melchoir J, Spasov AA, Ostrovskij OV, et al. Double-blind, placebo-controlled pilot and phase III study of activity of standardized Andrographis paniculata Herba Nees extract fixed combination (Kan Jang) in the treatment of uncomplicated upper-respirator
  9. Calabrese C, Berman SH, Babish JG, et al. A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother Res 2000;14:333-8. PubMed
  10. Gabrielian ES, Shukarian AK, Goukasova GI, et al. A double blind, placebo-controlled study of Andrographis paniculata fixed combination Kan Jang in the treatment of acute upper respiratory tract infections including sinusitis. Phytomedicine 2002;9:589-97 PubMed
  11. Poolsup N, Suthisisang C, Prathanturarug S, et al. Andrographis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: systematic review of randomized controlled trials. J Clin Pharm Ther 2004;29:37-45. PubMed
  12. Coon JT, Ernst E. Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med 2004;70:293-8.
  13. Kligler, B., Ulbricht, C., Basch, E., Kirkwood, C. D., Abrams, T. R., Miranda, M., Singh Khalsa, K. P., Giles, M., Boon, H., and Woods, J. Andrographis paniculata for the treatment of upper respiratory infection: a systematic review by the natural standa
  14. Burgos, R. A., Hancke, J. L., Bertoglio, J. C., Aguirre, V., Arriagada, S., Calvo, M., and Caceres, D. D. Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled tria
  15. Saxena, R. C., Singh, R., Kumar, P., Yadav, S. C., Negi, M. P., Saxena, V. S., Joshua, A. J., Vijayabalaji, V., Goudar, K. S., Venkateshwarlu, K., and Amit, A. A randomized double blind placebo controlled clinical evaluation of extract of Andrographis pa
  16. Tang, T., Targan, S. R., Li, Z. S., Xu, C., Byers, V. S., and Sandborn, W. J. Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine. Aliment.Pharmacol Ther 2011;33(2) PubMed
  17. Sandborn, W. J., Targan, S. R., Byers, V. S., Rutty, D. A., Mu, H., Zhang, X., and Tang, T. Andrographis paniculata extract (HMPL-004) for active ulcerative colitis. Am J Gastroenterol. 2013;108(1):90-98. PubMed
  18. Melchior, J., Palm, S., and Wikman, G. Controlled clinical study of standardized Andrographis paniculata extract in common cold - a pilot trial. Phytomedicine. 1997;3(4):315-318. PubMed
  19. Balap A, Atre B, Lohidasan S, et al. Pharmacokinetic and pharmacodynamic herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide with etoricoxib after oral administration in rats. J Ethnopharmacol. 2016 May 13;183:9-17. PubMed
  20. Bertoglio JC, Baumgartner M, Palma R, et al. Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-month double-blind placebo-controlled pilot study. BMC Neurol. 2016; 16(1):77. PubMed
  21. Suwankesawong W, Saokaew S, Permsuwan U, et al. Characterization of hypersensitivity reactions reported among Andrographis paniculata users in Thailand using Health Product Vigilance Center (HPVC) database. BMC Complement Altern Med. 2014; 14:515. PubMed
  22. Ciampi E, Uribe-San-Martin R, Cárcamo C, et al. Efficacy of andrographolide in not active progressive multiple sclerosis: a prospective exploratory double-blind, parallel-group, randomized, placebo-controlled trial. BMC Neurol 2020;20(1):173. PubMed
  23. Worakunphanich W, Thavorncharoensap M, Youngkong S, Thadanipon K, Thakkinstian A. Safety of Andrographis paniculata: A systematic review and meta-analysis. Pharmacoepidemiol Drug Saf 2021;30(6):727-739.
  24. More SJ, Tandulwadkar SS, Balap AR, Lohidasan S, Sinnathambi A, Mahadik KR. Effect of Andrographis paniculata extract and Andrographolide on the pharmacokinetics of Aceclofenac and Celecoxib in rats. Futur J Pharm Sci. 2023;9(1):1. PubMed
  25. Sundhani E, Nugroho AE, Nurrochmad A, Puspitasari I, Amalia Prihati D, Lukitaningsih E. Pharmacokinetic Herb-Drug Interactions of Glipizide with Andrographis paniculata (Burm. f.) and Andrographolide in Normal and Diabetic Rats by Validated HPLC Method. M PubMed
  26. Shang YX, Shen C, Stub T, et al. Adverse Effects of Andrographolide Derivative Medications Compared to the Safe use of Herbal Preparations of Andrographis paniculata: Results of a Systematic Review and Meta-Analysis of Clinical Studies. Front Pharmacol 20 PubMed

See these in context on the Andrographis monograph →

Coriander 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
  11. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
  12. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed

See these in context on the Coriander monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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