Keydigest Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Keydigest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Keydigest is a dietary supplement by Whole Body Research with 16 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Keydigest by Whole Body Research
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Keydigest is a blend of 16 digestive enzymes. They include Lipase (breaks down fats), Lactase (breaks down milk sugar), Phytase (affects mineral absorption), Acid Protease, Bacterial Protease, and Fungal Protease (all break down proteins), plus several others like Amylase, Cellulase, Beta-Glucanase, Xylanase, Hemicellulase, Glucoamylase, Alpha-Galactosidase, Invertase, Pectinase, and Diastase — each one targets different types of food compounds to aid breakdown in your digestive tract.
The capsule also contains Rice Bran and Vegetable Cellulose as inactive ingredients.
Does it work?
Strong evidence
The evidence for these enzymes in supplement form is mixed and often thin. Lactase is effective for lactose intolerance — that's the one with solid support.
For the others — Lipase, Phytase, and the various proteases — the data we hold shows insufficient reliable evidence to rate their effectiveness for the conditions they're marketed for, including inflammatory bowel disease, indigestion, iron or zinc deficiency, and skin aging. No effectiveness data are on file for several of the enzymes in this blend.
How safe is it?
Well-documented data
The enzymes in this product are generally well tolerated by most adults, though digestive upset or allergic reactions are possible with the proteases. Lactase is likely safe in pregnancy, but phytase should be avoided unless your doctor says otherwise — safety data during pregnancy are insufficient or absent for most of the other ingredients.
During breastfeeding, check with your doctor or pharmacist first; limited data exist for Lactase, Lipase, and the proteases in that setting. If you have a serious digestive condition, use this product only under medical guidance.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, because we hold no safety information for roughly half the enzymes in this product, run your medications through the checker on this page before you start to be sure.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Keydigest is a multi-enzyme blend with no documented interactions in our database, though we couldn't check all of its ingredients. Lactase in the formula is effective for lactose intolerance; the other enzymes lack strong evidence for most claimed uses.
If you're pregnant, planning to breastfeed, or have a digestive disorder, talk with your doctor or pharmacist before starting — they can weigh whether this supplement is right for your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 16 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Keydigest, straight from the product label.
| Brand | Whole Body Research |
|---|---|
| Net contents | 90 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 16, 2022 |
| DSLD ID | 268855 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Keydigest by Whole Body Research, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Beta-Glucanase | 0 NP | -- |
| Phytase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Acid Protease | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Pectinase | 0 NP | -- |
| Diastase | 0 NP | -- |
| Bacterial Protease | 0 NP | -- |
| Fungal Protease | 0 NP | -- |
Other ingredients: Rice Bran, Vegetable Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1-2 capsules with your meals.
Formulation
KEYDIGEST is made in the USA from the highest quality ingredients according to cGMP guidelines.
Made in USA
Reduce Gas and Bloating Aids Breakdown of Food Supports Digestive Function
Precautions
Warning: Consult your health care provider prior to use if you are pregnant, nursing, are thinking about getting pregnant, have any medical conditions, or are taking any medications.
Keep out of the reach of children.
Storage
Store in a cool, dry place. Avoid excessive heat.
Seals/Symbols
GMP Good Manufacturing Practice Product
General Statements
Available online at: WholeBodyResearch.com Questions or Comments: 1-800-240-7721
FDA Disclaimer Statement
These statements have not been evaluated by The Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Keydigest by Whole Body Research label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Keydigest by Whole Body Research
These are the 16 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Amylase
Lipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsCellulase
Beta-Glucanase
Phytase
No knowninteractions
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and c...
Phytase monograph & interactionsXylanase
Hemicellulase
Glucoamylase
Acid Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Acid Protease monograph & interactionsAlpha-Galactosidase
Invertase
Pectinase
Diastase
Bacterial Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Bacterial Protease monograph & interactionsFungal Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Fungal Protease monograph & interactionsOther (inactive) ingredients: Rice Bran, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.
Keydigest by Whole Body Research Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Keydigest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Keydigest, from the product label.
Whole Body Research
See all Whole Body Research products- Name
- Whole Body Research
- City
- Chatsworth
- State
- CA
- ZipCode
- 91311
- Phone Number
- 1-800-240-7721
- Web Address
- wholebodyresearch.com
Keydigest by Whole Body Research: Common Questions
Does Keydigest by Whole Body Research interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Keydigest safe during pregnancy?
Can I take this while breastfeeding?
Does Keydigest actually help with digestion?
What are the main enzymes in Keydigest?
Can I get an allergic reaction to this product?
Is Keydigest safe for people with IBD?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Keydigest is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Keydigest’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographPhytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Keydigest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC