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Dietary supplement

Whole Body Glutamine Ingredients & Drug Interactions

by Whole Body Research

Powder Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Whole Body Glutamine is a dietary supplement by Whole Body Research with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Whole Body Glutamine by Whole Body Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Whole Body Glutamine contains one active ingredient: L-glutamine, an amino acid your body uses for muscle recovery, immune function, and intestinal health. There are no inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Glutamine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: stomach and intestinal lining health.
  • We looked for evidence on: Crohn disease, Irritable bowel syndrome (IBS), Peptic ulcers, Short bowel syndrome, Chemotherapy-induced diarrhea, Radiation-induced diarrhea — and 4 related terms.
  • The closest evidence on file: Glutamine is rated "Possibly Ineffective" for Crohn disease (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Radiation-induced diarrhea.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-induced diarrhea, Antiretroviral-associated diarrhea, Irritable bowel syndrome (IBS), Oral mucositis, and more.

The evidence supports glutamine for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the data shows it's possibly effective — meaning early results are promising but more research is needed to be certain.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated in healthy adults. You may experience belching, bloating, constipation, diarrhea, nausea, vomiting, or headache — these are the most common side effects reported.

At high doses (10–30 grams daily), GI upset is more likely. If you have kidney or liver disease, use this supplement only under your doctor's supervision.

There isn't enough safety data to recommend it during pregnancy or breastfeeding unless your doctor advises it. In people with bipolar disorder, high-dose glutamine has rarely triggered mood symptoms, so check with your healthcare provider if that applies to you.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant (seizure) medications, check with your doctor or pharmacist before taking this product — glutamine may theoretically reduce how well these drugs work, though this hasn't been confirmed in patients yet. This is a moderate-risk concern.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine may help with sickle cell disease and possibly with muscle wasting or recovery after surgery or critical illness. It's generally well tolerated, but GI side effects are common, especially at high doses.

If you take seizure medication, have kidney or liver disease, or have bipolar disorder, talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Whole Body Glutamine, straight from the product label.

Brand Whole Body Research
Net contents 150 Gram(s); 0.33 lbs
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47952
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Whole Body Glutamine by Whole Body Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
10 Gram(s)
Servings per container
30
IngredientAmount% DV
L-Glutamine5000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Whole Body Glutamine(TM) helps your digestive health by helping to protect the stomach and intestinal lining.

General Statements

Supplementation of Whole Body Glutamine, in conjunction with our digestive health products, can also help improve overall health and well-being. For best results, take the suggested dose every day as part of your healthy routine.

Made in USA

For stomach and intestinal health

30 Servings

Precautions

Warning: Consult your health care provider prior to use if you are pregnant, nursing, are thinking about getting pregnant, have any medical conditions. or are taking any medications.

Keep out of the reach of children.

Seals/Symbols

GMP - GOOD MANUFACTURING PRACTICE - PRODUCT

General

V11

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions for use: Take 1-2 scoops (5-10 grams) with 8-16 oz. of water on an empty stomach once daily or as directed by your health care provider.

See for yourself

Whole Body Glutamine by Whole Body Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Whole Body Glutamine by Whole Body Research

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Whole Body Glutamine by Whole Body Research Drug Interactions

Want to check YOUR meds against Whole Body Glutamine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Whole Body Glutamine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Whole Body Glutamine, from the product label.

Pharmacist Counseling Corner

Whole Body Glutamine by Whole Body Research: Common Questions

Does Whole Body Glutamine by Whole Body Research interact with any medications?
Yes. Based on its ingredients, Whole Body Glutamine has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Whole Body Glutamine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does L-glutamine actually do?
L-glutamine is an amino acid your body uses for muscle repair, immune support, and maintaining your intestinal lining. It's especially studied for helping people recover from surgery, critical illness, and certain conditions like sickle cell disease and HIV/AIDS-related muscle wasting.
Will I get GI side effects?
Belching, bloating, constipation, diarrhea, nausea, and headache are the most common side effects, especially when taking higher doses. A small number of trial participants experienced these at doses of 10–30 grams daily. Most people tolerate lower doses without trouble.
Is it safe during pregnancy or breastfeeding?
The safety data for supplemental glutamine during pregnancy and breastfeeding is incomplete. The product facts rate it likely safe, but your doctor or pharmacist should weigh this for your situation before you start.
Can I take this if I have kidney or liver disease?
If you have kidney or liver disease, you should only use this supplement under medical supervision — your doctor or pharmacist can assess whether it's right for you and what dose is safe.
Does glutamine actually help with athletic performance?
The effectiveness data we hold focuses on sickle cell disease, HIV/AIDS wasting, postoperative recovery, and critical illness — athletic performance isn't included in what we can speak to. Talk with your healthcare provider about whether it fits your specific goals.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Whole Body Glutamine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Whole Body Glutamine label
Go deeper

The Full Monographs Behind Whole Body Glutamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Whole Body Glutamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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