No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Glutathione 500 mg Ingredients & Drug Interactions

by Dr. Clark Store

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

L-Glutathione 500 mg is a dietary supplement by Dr. Clark Store with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Glutathione 500 mg by Dr. Clark Store

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: Setria L-Glutathione at 500 mg per capsule. L-glutathione is a small protein (called a tripeptide) made by your cells — it acts as an antioxidant, helping protect cells from damage and supporting your body's natural detoxification processes.

The capsule itself is vegetarian delayed-release material, designed to break down in your small intestine rather than your stomach.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutathione's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glutathione for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Cisplatin-induced neurotoxicity — rated "Possibly Effective" (Natural Medicines).

The evidence for L-glutathione is mixed. It's rated possibly effective for reducing nerve damage caused by the chemotherapy drug cisplatin.

For other conditions — nonalcoholic fatty liver disease, Alzheimer disease, athletic performance, and cataracts — the evidence isn't established in the data we hold. If you're considering this product for one of those uses, talk with your doctor about whether the current research supports trying it.

The evidence, ingredient by ingredient Glutathione

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral L-glutathione appears generally well tolerated in the short term, though long-term safety hasn't been fully worked out. The safety information for pregnancy isn't sufficient, so the data advises against use unless your doctor says otherwise.

The same goes for breastfeeding — there isn't enough reliable information, so caution and avoidance are recommended. One important note: inhaled (nebulized) glutathione can narrow the airways and cause shortness of breath or cough in people with asthma; this product is a capsule, not inhaled, but that's worth knowing if you ever encounter other forms.

Side effects, ingredient by ingredient Glutathione

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient in this product. That doesn't mean none exist — just that we haven't found documented ones.

If you're on any regular medications, a quick conversation with your pharmacist is never a bad idea.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

L-glutathione may be worth considering if your doctor has suggested it for cisplatin-related nerve damage. For other uses, the evidence isn't clear yet.

If you're pregnant, breastfeeding, or have asthma, talk with your doctor or pharmacist before starting — the safety data for pregnancy and breastfeeding advises against it unless your doctor specifically recommends it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Glutathione 500 mg, straight from the product label.

Brand Dr. Clark Store
Barcode (UPC) 652384104302
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 219868
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Glutathione 500 mg by Dr. Clark Store, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
652384104302
IngredientAmount% DV
Setria L-Glutathione500 mg--

Other ingredients: Vegetarian delayed release Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule, preferably with a meal, or as directed by a healthcare professional.

Storage

Store at room temperature.

Precautions

Keep away from children.

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.

Seals/Symbols

GMP Quality Assured

Made in USA

Formulation

Our products don’t contain flow agents like magnesium stearate. Not now, not ever.

Delayed release

General Statements

Leader in purity Established by Dr. Clark’s Family in 1993

Company does not adopt any Dr. Clark claims.

Formula

L-Glutathione reduced Setria 500 mg

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Setria is a registered trademark of KYOWA HAKKO BIO CO., LTD.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

L-Glutathione 500 mg by Dr. Clark Store label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Glutathione 500 mg by Dr. Clark Store

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Setria L-Glutathione

No known
interactions
500 mg per serving

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

Setria L-Glutathione monograph & interactions

Other (inactive) ingredients: Vegetarian delayed release Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Glutathione 500 mg by Dr. Clark Store Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Glutathione 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Glutathione 500 mg, from the product label.

Dr. Clark Store

See all Dr. Clark Store products
Name
Self Health Resource Center
Street Address
1055 Bay Blvd., Ste A
City
Chula Vista
State
CA
ZipCode
91911
Phone Number
866-372-5275
Web Address
www.DrClarkStore.com
Pharmacist Counseling Corner

L-Glutathione 500 mg by Dr. Clark Store: Common Questions

Does L-Glutathione 500 mg by Dr. Clark Store interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Glutathione 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Glutathione 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
The safety information for pregnancy isn't sufficient, so it's best avoided unless your doctor advises otherwise. Talk with your doctor or pharmacist before taking it if you're pregnant or trying to become pregnant.
Is it safe to use while breastfeeding?
There isn't enough reliable safety information for breastfeeding, so caution and avoidance are advised. Check with your doctor or pharmacist before taking it if you're nursing.
Does L-glutathione work for boosting athletic performance?
The evidence isn't established in the data we hold. There isn't enough reliable evidence to say whether it helps with athletic performance.
What does L-glutathione actually do in my body?
L-glutathione is an antioxidant your cells make naturally — it helps protect them from damage and supports your body's detoxification processes. This product supplies an extra dose of it in supplement form.
Can I take this long-term?
Short-term use appears generally well tolerated, but long-term safety hasn't been fully worked out. If you're thinking about taking it regularly for months or longer, ask your doctor or pharmacist whether that makes sense for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Glutathione 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Glutathione 500 mg label
Go deeper

The Full Monographs Behind L-Glutathione 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Glutathione 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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