No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Glutathione Ingredients & Drug Interactions

by HoltraCeuticals

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

L-Glutathione is a dietary supplement by HoltraCeuticals with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Glutathione by HoltraCeuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 1 active ingredient: Setria, a form of L-glutathione, an antioxidant your body makes naturally. The capsule also contains inactive ingredients — microcrystalline cellulose, magnesium stearate, and silicon dioxide — which are binders and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutathione's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glutathione for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Cisplatin-induced neurotoxicity — rated "Possibly Effective" (Natural Medicines).

The evidence here is mixed. Glutathione is possibly effective for reducing nerve damage (neurotoxicity) caused by the chemotherapy drug cisplatin.

For nonalcoholic fatty liver disease (NAFLD), Alzheimer disease, athletic performance, and cataracts, the evidence isn't established in the data we hold.

The evidence, ingredient by ingredient Glutathione

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral glutathione appears generally well tolerated in the short term, but we don't have solid long-term safety data on it. During pregnancy, the safety data advises against use unless your doctor advises otherwise.

The same caution applies to breastfeeding — there isn't enough reliable information, so avoidance is advised. One note: if you were to inhale nebulized glutathione (not the form in this capsule), it can narrow airways and cause shortness of breath or cough, especially in people with asthma.

Side effects, ingredient by ingredient Glutathione

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we checked. That said, always run your exact prescriptions through the tool on this page before adding any new supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

If your doctor has mentioned glutathione for cisplatin-induced nerve damage, this is worth discussing with them. For other uses, the evidence isn't clear yet.

Pregnant or breastfeeding? Talk to your pharmacist or doctor first — the safety data doesn't support use without their guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Glutathione, straight from the product label.

Brand HoltraCeuticals
Barcode (UPC) 615033607180
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 319567
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Glutathione by HoltraCeuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
615033607180
IngredientAmount% DV
Setria250 mg--

Other ingredients: Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 1 or more capsules per day or as recommended by your health care professional.

Formulation

Formulated to be free of allergens derived from: Gluten, corn, yeast, artificial colors and flavors.

Supports immune function

Vcaps

Precautions

If you are pregnant or nursing, consult your physician before taking this product.

As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used.

Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.

Keep out of reach of children.

This product was sealed for your protection. Do not use if outer logoed neck seal or inner-seal is missing or damaged.

Storage

Keep container tightly closed. Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Setria is a registered trademark of Kyowa Hakko Bio Co. Ltd.

Formula

Setria

General Statements

To reorder visit: HoltraCeuticals.com

See for yourself

L-Glutathione by HoltraCeuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Glutathione by HoltraCeuticals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Setria

No known
interactions
250 mg per serving Form: Glutathione, Reduced

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

Setria monograph & interactions

Other (inactive) ingredients: Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Glutathione by HoltraCeuticals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Glutathione. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Glutathione, from the product label.

HoltraCeuticals

See all HoltraCeuticals products
Name
Holtorf Medical Group Centers for Hormone Balance, Hypothyroidism and Fatigue
Street Address
2232 E. Maple Ave
City
El Segundo
State
CA
ZipCode
90245
Web Address
HoltraCeuticals.com
Pharmacist Counseling Corner

L-Glutathione by HoltraCeuticals: Common Questions

Does L-Glutathione by HoltraCeuticals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Glutathione. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Glutathione contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this glutathione safe to take while pregnant?
There isn't enough reliable safety information to say yes. The data advises against it unless your doctor advises otherwise. Talk to your doctor or pharmacist before taking it during pregnancy.
Can I take this while breastfeeding?
No, there isn't enough reliable safety information during breastfeeding. Caution and avoidance are advised. Check with your pharmacist or doctor before use.
Does glutathione actually work for anything?
It's possibly effective for reducing nerve damage caused by the chemotherapy drug cisplatin. For other uses listed here — liver disease, Alzheimer disease, athletic performance, and cataracts — the evidence isn't established yet.
What is Setria?
Setria is the brand name for the L-glutathione in this capsule. Glutathione is an antioxidant your body makes on its own.
Is this form of glutathione safe long-term?
Short-term use appears generally well tolerated, but we don't have solid data on long-term safety with oral forms. If you're considering taking it regularly, check with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Glutathione is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Glutathione label
Go deeper

The Full Monographs Behind L-Glutathione’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Glutathione's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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