L-Histidiine 600 mg Ingredients & Drug Interactions
by NOW
What is this page for?
First and foremost: checking L-Histidiine 600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Histidiine 600 mg is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for skin conditions like eczema, anemia related to kidney disease, allergy and inflammation support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of L-Histidiine 600 mg by NOW
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: L-Histidine HCl, an amino acid (a building block of protein). The supplement also includes inactive ingredients—microcrystalline cellulose, hypromellose, stearic acid, and silicon dioxide—which are standard capsule fillers and binders.
Does it work?
Couldn't assess
The evidence on L-Histidine is mixed. It's rated possibly effective for cholera.
For other uses—atopic dermatitis (eczema), kidney failure, and rheumatoid arthritis—the data we hold shows insufficient reliable evidence to rate whether it works. If you're considering this supplement for a specific condition, check with your doctor or pharmacist about what the current evidence actually supports.
How safe is it?
Some data gaps
L-Histidine from food is considered likely safe as part of normal nutrition. At supplement doses like the 600 mg in this product, though, the safety data is thin.
The available information advises caution because supplemental amounts haven't been well studied. Pregnancy and lactation: L-Histidine at dietary levels is likely safe, but talk with your doctor before taking a supplement dose during pregnancy or while nursing, since higher amounts aren't well established.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredient we could check. That doesn't mean none exist—just that this supplement hasn't shown documented interactions with medications in the resources we hold.
If you take any prescription drugs, confirm with your own doctor or pharmacist before adding this to your routine.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.
This product may be worth considering if your doctor has advised you to take L-Histidine for a specific reason—such as cholera. The supplement doesn't interact with medications in our data, but the evidence for most other uses is weak or missing.
Before you start, talk with your doctor or pharmacist about whether it makes sense for your situation and whether the dose is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Histidiine 600 mg, straight from the product label.
| Brand | NOW |
|---|---|
| Barcode (UPC) | 733739001214 |
| Net contents | 60 Veg Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 292049 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Histidiine 600 mg by NOW, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Histidine | 600 mg | -- |
| L-Histidine HCl | 833 mg | -- |
Other ingredients: Hypromellose, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 1 capsule daily with or without food.
Formula
L-Histidine is an essential amino acid that is best known for its role in the production of histamine, an important mediator of immune system responses. Histidine is also critical for normal brain function, as well as for the maintenance of a healthy skin barrier. In addition, histidine plays important roles in muscle function, cardiovascular health, protection against free radicals, and the elimination of heavy metals from the body.
Essential Amino Acid
FDA Disclaimer Statement
These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution: For adults only.
Consult physician if pregnant/nursing, taking medication (especially anticoagulant and anti-platelet drugs), have a medical condition (especially bleeding disorders), or if planning to have surgery.
Keep out of reach of children.
Produced in a GMP facility that processes other ingredients containing these allergens.
Formulation
Non-GMO
Vegetarian/Vegan
Made with quality tested in the USA with globally sourced ingredients.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.
Natural color variation may occur in this product.
Critical for normal brain function Immune System Support
FDA Statement of Identity
A Dietary Supplement
General Statements
Family owned since 1968.
Storage
Store in a cool, dry place after opening.
Seals/Symbols
GMP Quality Assured
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Histidiine 600 mg by NOW label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Histidiine 600 mg by NOW
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
L-Histidine
No knowninteractions
Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from...
L-Histidine monograph & interactionsOther (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
L-Histidiine 600 mg by NOW Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in L-Histidiine 600 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for L-Histidiine 600 mg, from the product label.
NOW
See all NOW products- Name
- NOW FOODS
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- www.nowfoods.com
L-Histidiine 600 mg by NOW: Common Questions
Does L-Histidiine 600 mg by NOW interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is L-Histidine safe to take at this dose?
Can I take this while pregnant or breastfeeding?
What is L-Histidine used for?
Does this interact with my medications?
What are the inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Histidiine 600 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Histidiine 600 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Histidiine 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC