L-Lysine Ingredients & Drug Interactions
by OL Olympian Labs Incorporated
What is this page for?
First and foremost: checking L-Lysine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Lysine is a dietary supplement by OL Olympian Labs Incorporated with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against L-Lysine by OL Olympian Labs Incorporated
Ask about any prescription or over-the-counter medication and we check it for interactions with L-Lysine by OL Olympian Labs Incorporated — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of L-Lysine by OL Olympian Labs Incorporated
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This supplement contains one active ingredient: L-lysine, an amino acid your body uses to build and repair tissues. L-lysine is available from food sources like meat, fish, and dairy, but this product delivers it in concentrated form as a capsule.
The capsule also contains inactive ingredients—microcrystalline cellulose, rice flour, ascorbyl palmitate, and silica—which serve as fillers and binders.
Does it work?
Not established
L-lysine is possibly effective for cold sores (herpes labialis). The evidence we hold doesn't establish its usefulness for child growth, pressure ulcers, or diabetic foot ulcers — there isn't enough reliable data to say either way on those.
How safe is it?
Well-documented data
L-lysine is generally well tolerated at typical doses. High amounts may cause stomach upset, though, and long-term safety at supplement levels hasn't been well studied.
The most common side effects reported from oral use are abdominal pain, diarrhea, and indigestion. One case report linked high-dose oral lysine to a kidney problem, though this is rare.
During pregnancy, eating lysine-containing foods is fine, but supplement safety hasn't been well studied — talk with your doctor before taking it as a supplement. There also isn't enough reliable information on supplement use while breastfeeding, so caution is advised and a conversation with your doctor or pharmacist would be wise.
Meds to double-check
Minor interactions only
If you take a 5-HT4 agonist (a medication for certain stomach or gut issues), confirm with your pharmacist or doctor before using L-lysine — it may reduce how well the drug works.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.
If you're looking to manage cold sores, L-lysine is possibly effective and generally well tolerated. If you're taking a 5-HT4 agonist medication, check with your pharmacist or doctor before starting.
Pregnant or breastfeeding? Talk it over with your doctor first, since supplement safety data is limited.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 1, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Lysine, straight from the product label.
| Brand | OL Olympian Labs Incorporated |
|---|---|
| Barcode (UPC) | 710013032164 |
| Net contents | 60 Capsule(s); 500 mg |
| Market status | On market |
| Date entered into DSLD | Jun 1, 2012 |
| DSLD ID | 9630 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Lysine by OL Olympian Labs Incorporated, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Lysine | 500 mg | -- |
Other ingredients: Microcrystalline Cellulose, Rice Flour, Ascorbyl Palmitate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
OLYMPIAN LABS GUARANTEE: Olympian Labs guarantees that all OL products are of the highest quality ingredients and lab assayed to ensure that what we say on the label is actually in the product.
When you buy an Olympian Labs product, you can be sure you are buying the best.
Free Form Amino Acid
L-Lysine is an essential free form amino acid that is a necessary building block for all protein in the body. L-Lysine plays a major role in calcium absorption, building muscle protein and the body's production of hormones, enzymes, and antibodies. L-Lysine also reduces the absorption of L-Arginine, an amino acid that can fuel herpes and cold sore outbreaks.
Confused on what to take? Check yourself at: WhatVitaminsAreRightForYou.com
Made in USA
Formulation
All Olympian Labs products are free from most allergens such as corn, yeast, barley, gluten, wheat, soy, lactose, all milk products, citrus, fish, egg products, as well as added flavorings, sugars, sweeteners, salt, preservatives, salicylates, artificial colors and coatings.
Storage
STORE IN A COOL, DRY PLACE.
Seals/Symbols
VEGETARIAN & KOSHER CAPSULES V
Since 1992 OL
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Suggested/Recommended/Usage/Directions
SUGGESTED USE: As a dietary supplement, take one (1) capsule daily, or as directed by a healthcare professional.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Lysine by OL Olympian Labs Incorporated label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Lysine by OL Olympian Labs Incorporated
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
L-Lysine
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Rice Flour, Ascorbyl Palmitate, Silica. These complete the product’s ingredient list but are not active constituents.
L-Lysine by OL Olympian Labs Incorporated Drug Interactions
HelloPharmacist Interaction Report
L-Lysine by Olympian Labs Incorporated has one documented interaction worth knowing about, involving a specific class of drugs called 5-HT4 agonists.
Animal research suggests lysine may work against how these drugs function, potentially reducing their effects. This is a Minor interaction, so it's not an emergency, but worth a conversation with your doctor or pharmacist if you're on one of these medications.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 1 individual medication.
If you take a 5-HT4 agonist, run it through the medication checker on this page or confirm with your pharmacist before starting lysine. Otherwise, check your exact medications with the search tool below to be sure.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against L-Lysine?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in L-Lysine interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in L-Lysine interact with drugs. Each result below shows which ingredient is responsible. L-Lysine
TegaserodZelnorm
How Tegaserod interacts with L-Lysine — through 1 ingredient. Tap an ingredient for the detail:
L-lysine5-ht4 Agonists Minor
Interaction Summary
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Read the full L-lysine + Tegaserod interactionEach ingredient & the kinds of drugs it affects
For each ingredient in L-Lysine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Lysine
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for L-Lysine, from the product label.
OL Olympian Labs Incorporated
See all OL Olympian Labs Incorporated products- Name
- OLYMPIAN LABS INCORPORATED
- Street Address
- P.O. Box 12461
- City
- Scottsdale
- State
- AZ
- ZipCode
- 85267
- Phone Number
- 1-800-473-5883
- Web Address
- www.OlympianLabs.com
L-Lysine by OL Olympian Labs Incorporated: Common Questions
Does L-Lysine by OL Olympian Labs Incorporated interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will L-lysine actually help my cold sores?
What side effects should I watch for?
Is it safe to take while pregnant?
Can I take it while breastfeeding?
What is L-lysine and where does it come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Lysine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Lysine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Lysine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC