L-Lysine SAP Ingredients & Drug Interactions
by NFH
What is this page for?
First and foremost: checking L-Lysine SAP against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Lysine SAP is a dietary supplement by NFH with 1 active ingredient. Its ingredients are commonly taken for cold sores (herpes labialis), genital herpes outbreaks, supporting protein and collagen formation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against L-Lysine SAP by NFH
Ask about any prescription or over-the-counter medication and we check it for interactions with L-Lysine SAP by NFH — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of L-Lysine SAP by NFH
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
L-Lysine SAP is a single-ingredient supplement — just L-lysine, an amino acid your body needs for protein and immune function. The capsules also contain inactive ingredients: vegetable magnesium stearate, silicon dioxide, vegetable hypromellose, and purified water.
Does it work?
Couldn't assess
L-lysine is possibly effective for cold sores (herpes labialis). For other uses listed — child growth, pressure ulcers, and diabetic foot ulcers — the evidence isn't strong enough to rate, so we don't know yet whether it actually helps.
How safe is it?
Well-documented data
L-lysine is generally well tolerated at normal doses. At very high amounts, it may cause stomach upset, and long-term safety at higher doses isn't well studied.
The most common side effects are abdominal pain, diarrhea, and indigestion. There is one reported case of kidney inflammation linked to oral lysine, though this is very rare.
Supplement safety in pregnancy and breastfeeding hasn't been well studied — food sources of lysine are fine, but before taking this supplement during pregnancy or while breastfeeding, talk with your doctor, since there isn't enough data to know either way.
Meds to double-check
Minor interactions only
If you take 5-HT4 agonist medications (used for certain digestive issues), check with your doctor or pharmacist before starting this supplement — lysine may reduce their effect, though the evidence is limited.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
L-lysine may help with cold sores if you want to try it. If you take any medications for digestive function — especially 5-HT4 agonists — clear this supplement with your doctor or pharmacist first.
It's generally well tolerated at typical doses, but high amounts may upset your stomach, and pregnancy and breastfeeding safety data are limited.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Lysine SAP, straight from the product label.
| Brand | NFH |
|---|---|
| Barcode (UPC) | 856711001603 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2023 |
| DSLD ID | 273160 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Lysine SAP by NFH, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Lysine | 1000 mg | -- |
Other ingredients: Vegetable Magnesium Stearate, Silicon Dioxide, Vegetable Hypromellose, Water, Purified
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
L-Lysine SAP is n essential amino acid for the maintenance of collagen, skin, bone, tendon, and cartilage health. L-Lysine SAP promotes a healthy immune system.
All ingredients listed for this product lot number have been tested by a third-party laboratory for identity, potency, and purity.
Contains no: Gluten, soy, wheat, corn, eggs, dairy, yeast, citrus, preservatives, artificial flavor or color, starch, or sugar.
This product in non-GMO and vegan friendly.
This product in non-GMO and vegan friendly.
Color, size and smell may vary from one lot to another.
Suggested/Recommended/Usage/Directions
Directions for use: Adults: Take 2 capsules one to three times daily or as directed by your healthcare practitioner. Consult a healthcare practitioner for use beyond 6 months. Take on an empty stomach.
Precautions
Cautions and warnings: Consult a healthcare practitioner prior to use if you are following a low protein diet; or if you are pregnant or breast-feeding.
Do not use if seal is broken.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Amino acid
FDA Statement of Identity
Dietary Supplement
General Statements
NPN 80028551
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Lysine SAP by NFH label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Lysine SAP by NFH
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
L-Lysine
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine monograph & interactionsOther (inactive) ingredients: Vegetable Magnesium Stearate, Silicon Dioxide, Vegetable Hypromellose, Water, Purified. These complete the product’s ingredient list but are not active constituents.
L-Lysine SAP by NFH Drug Interactions
HelloPharmacist Interaction Report
L-Lysine SAP by NFH contains one ingredient — L-lysine — that has a documented interaction.
The concern is with 5-HT4 agonists (medications that work on a specific serotonin receptor in your gut). Animal research suggests lysine may reduce how well these drugs work, though the evidence is limited and the interaction is rated Minor.
Read the full breakdown — every affected drug type, severity by severity
If you take any 5-HT4 agonists for digestive symptoms, mention this supplement to your doctor or pharmacist before starting it so you can decide together whether it's right for you. Use the medication checker on this page to see your exact drugs, and have that conversation with your healthcare provider.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against L-Lysine SAP?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in L-Lysine SAP interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in L-Lysine SAP interact with drugs. Each result below shows which ingredient is responsible. L-Lysine
TegaserodZelnorm
How Tegaserod interacts with L-Lysine SAP — through 1 ingredient. Tap an ingredient for the detail:
L-lysine5-ht4 Agonists Minor
Interaction Summary
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Read the full L-lysine + Tegaserod interactionEach ingredient & the kinds of drugs it affects
For each ingredient in L-Lysine SAP with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Lysine
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for L-Lysine SAP, from the product label.
NFH
See all NFH products- Name
- NFH - Nutritional Fundamentals for Health, Inc.
- Street Address
- 351 Joseph-Carrier
- City
- Vaudreuil
- State
- QC
- ZipCode
- J7V 5V5
- Phone Number
- 1-866-510-3123
- Web Address
- nfh.ca
L-Lysine SAP by NFH: Common Questions
Does L-Lysine SAP by NFH interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
Will this actually help my cold sores?
What are the most common side effects?
Does this supplement work for pressure ulcers or diabetic foot ulcers?
Is there anything else in this capsule besides lysine?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Lysine SAP is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Lysine SAP’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Lysine SAP's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lysine 7 references
- Thein DJ, Hurt WC. Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Oral Surg Oral Med Oral Pathol 1984;58:659-66. PubMed
- McCune MA, Perry HO, Muller SA, O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366-73.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol 1984;120:48-51. DOI
- Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
- Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Dermatologica 1987;175:183-90. DOI
- Lo JC, Chertow GM, Rennke H, Seifter JL. Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. Am J Kidney Dis 1996;28:614-7. PubMed
- Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC