L-Methionine 550 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking L-Methionine 550 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Methionine 550 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for acetaminophen (tylenol) overdose support, liver health, urinary tract acidification.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of L-Methionine 550 mg by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This is a straightforward, single-ingredient supplement: 550 mg of L-methionine per capsule. L-methionine is an amino acid — a building block your body uses to make proteins and other compounds.
The capsule itself is made from bovine gelatin.
Does it work?
Moderate evidence
The evidence for L-methionine is mixed and limited. Research suggests it may help reduce the risk of neural tube birth defects (malformations of the spine and brain in developing babies), though the data is not conclusive.
For other uses — acetaminophen poisoning, hay fever, asthma, and colorectal cancer — there simply isn't enough reliable evidence to say whether it works. If you're considering this for a specific health goal, talk it over with your doctor to see if the evidence supports its use for your situation.
How safe is it?
Well-documented data
When you eat methionine in food, it's well tolerated by your body. High-dose supplements, though, are a different story and should only be used under medical guidance.
The most common side effects with supplement doses are dizziness, drowsiness, low blood pressure, irritability, and vomiting; headache, elevated homocysteine levels (a heart disease risk factor), and increased calcium in the urine are also possible. Serious adverse effects like brain swelling (cerebral edema) are rare but have been reported.
During pregnancy, food amounts of methionine are fine, but the safety of supplement doses hasn't been proven — talk with your doctor or pharmacist about whether this dose is right for you. Similarly, the safety of supplement doses while breastfeeding hasn't been well studied, so personalized guidance from your healthcare provider is important.
Meds to double-check
No known interactions
No interactions are documented for L-methionine in our data. However, given that this ingredient can lower blood pressure and raise homocysteine levels, confirm with your own doctor or pharmacist before taking it if you're on blood pressure medications or have cardiovascular disease.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
L-Methionine is a single amino acid with limited but interesting evidence for neural tube defect prevention. It's well tolerated at food doses but carries real side-effect risks at higher supplement levels — especially dizziness, low blood pressure, and elevated homocysteine.
If you're pregnant, breastfeeding, or taking medications for blood pressure or heart health, talk with your doctor or pharmacist before starting this supplement.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Methionine 550 mg, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Net contents | 300 Gelatin Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 22, 2021 |
| DSLD ID | 254613 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Methionine 550 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Methionine | 1100 mg | -- |
Other ingredients: Bovine Gelatin Capsules
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Clean & pure bulk supplements
Precautions
Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.
Consult your physician before use.
Keep out of reach of children!
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Free of: Sugar, soy, dairy, yeast, gluten or additives
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 2 capsules once daily, or as directed by a physician.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Methionine 550 mg by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Methionine 550 mg by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Amounts shown are per serving.
L-Methionine
No knowninteractions
Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a norma...
L-Methionine monograph & interactionsOther (inactive) ingredients: Bovine Gelatin Capsules. These complete the product’s ingredient list but are not active constituents.
L-Methionine 550 mg by BulkSupplements.com Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in L-Methionine 550 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for L-Methionine 550 mg, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
L-Methionine 550 mg by BulkSupplements.com: Common Questions
Does L-Methionine 550 mg by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does L-methionine help prevent birth defects?
What are the most common side effects?
Is this safe to take while breastfeeding?
Can L-methionine raise my heart disease risk?
What does L-methionine do in your body?
Does this supplement have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Methionine 550 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Methionine 550 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Methionine 550 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Methionine 12 references
- La Vecchia C, Negri E, Franceschi S, Decarli A. Case-control study on influence of methionine, nitrite, and salt on gastric carcinogenesis in northern Italy. Nutr Cancer 1997;27:65-8. PubMed
- Btaiche IF, Khalidi N. Parenteral nutrition-associated liver complications in children. Pharmacotherapy 2002;22:188-211.. PubMed
- Cottington EM, LaMantia C, Stabler SP, et al. Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol 2002;22:1046-50.. PubMed
- Anon. Should methionine be added to paracetamol formulations? Drug Ther Perspect 1997;10:11-3. DOI
- Smulders, Y. M., Rakic, M., Slaats, E. H., Treskes, M., Sijbrands, E. J., Odekerken, D. A., Stehouwer, C. D., and Silberbusch, J. Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and c
- McAuley, D. F., Hanratty, C. G., McGurk, C., Nugent, A. G., and Johnston, G. D. Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. J.Toxicol.Clin.Toxicol. 1999;37(4):435-440. PubMed
- Hanratty, C. G., McGrath, L. T., McAuley, D. F., Young, I. S., and Johnston, G. D. The effects of oral methionine and homocysteine on endothelial function. Heart 2001;85(3):326-330. PubMed
- Ward, M., McNulty, H., McPartlin, J., Strain, J. J., Weir, D. G., and Scott, J. M. Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study. Int.J.Vitam.Nutr.Res. 2001;71(1):82-86. PubMed
- Yaghmai, R., Kashani, A. H., Geraghty, M. T., Okoh, J., Pomper, M., Tangerman, A., Wagner, C., Stabler, S. P., Allen, R. H., Mudd, S. H., and Braverman, N. Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient
- Talukdar R, Murthy HV, Reddy DN. Role of methionine containing antioxidant combination in the management of pain in chronic pancreatitis: a systematic review and meta-analysis. Pancreatology 2015;15(2):136-44. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: The National Academies Press, 2005. Available at: https://doi.org/10.17226 DOI
- Khairan P, Sobue T, Eshak ES, et al. Association of B Vitamins and Methionine Intake with the Risk of Gastric Cancer: The Japan Public Health Center-based Prospective Study. Cancer Prev Res (Phila) 2022;15(2):101-110. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC