No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Ornithine HCL Ingredients & Drug Interactions

by PureBulk.com

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Ornithine HCL is a dietary supplement by PureBulk.com with 1 active ingredient. Its ingredients are commonly taken for athletic performance and recovery, reducing fatigue, sleep and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Ornithine HCL by PureBulk.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-Ornithine Hydrochloride, an amino acid your body uses in several pathways. It's the single component doing the work here — no other actives are in the mix.

The powder form means you're getting ornithine with no fillers or binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Ornithine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Ornithine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).

The evidence points to ornithine being possibly effective for athletic performance — that's the strongest claim the data supports. For dry skin, insomnia, and periodontitis (gum disease), the evidence isn't established enough to say whether it helps or not.

If you're considering it for something other than athletic performance, talk it over with your doctor about whether it makes sense for you.

The evidence, ingredient by ingredient Ornithine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Ornithine HCL is generally well tolerated when you take it short-term. Long-term safety hasn't been well studied, so we don't have solid data on what happens if you use it for months or years on end.

During pregnancy and breastfeeding, there isn't enough safety data to know either way — the safety data advises against use during both. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this supplement.

Side effects, ingredient by ingredient Ornithine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-Ornithine HCL. That said, check your exact medications with the search tool on this page to be sure, and talk with your doctor or pharmacist if you take anything unusual or new.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and some safety-information gaps remain.

L-Ornithine HCL may be worth trying if you're looking to support athletic performance, since that's where the evidence is strongest. If you're pregnant, breastfeeding, or planning long-term use, check in with your doctor or pharmacist first — the safety data for those situations just isn't there yet.

Run your medications through the checker on this page, and reach out to your own healthcare provider if you have questions about whether it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Ornithine HCL, straight from the product label.

Brand PureBulk.com
Net contents 100 g; 3.53 oz.
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 23144
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Ornithine HCL by PureBulk.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
800 mg
Maximum serving Sizes:
800 mg
Servings per container
125
IngredientAmount% DV
L-Ornithine Hydrochloride800 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

CAUTION:Do not use if you have a herpes infection or cold sores.

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult your physician before use.

Keep out of reach of children.

Storage

Storage: Keep dry, cool & dark

Formulation

Free of: sugar, soy, dairy, yeast, gluten, corn and additives.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 800 mg (rounded 1/4 tsp) twice a day, or as directed by physician.

General Statements

US Standard Measuring Spoons Spoon Size (level) milligrams 1/8 teaspoon 325 1/4 teaspoon 651 1/2 teaspoon 1303

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

L-Ornithine HCL by PureBulk.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Ornithine HCL by PureBulk.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size800 mg Dosage formPowder Servings per container125 Amounts shown are per serving.

L-Ornithine Hydrochloride

No known
interactions
800 mg per serving

Ornithine is a non-essential amino acid your body makes naturally as part of the urea cycle, which helps remove ammonia. It is sold as a supplement fo...

L-Ornithine Hydrochloride monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Ornithine HCL by PureBulk.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Ornithine HCL. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Ornithine HCL, from the product label.

PureBulk.com

See all PureBulk.com products
Name
PureBulk.com
City
Roseburg
State
OR
ZipCode
97471
Phone Number
(541) 679-1500
Web Address
PureBulk.com
Pharmacist Counseling Corner

L-Ornithine HCL by PureBulk.com: Common Questions

Does L-Ornithine HCL by PureBulk.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Ornithine HCL. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Ornithine HCL contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does L-Ornithine actually help with exercise and athletic performance?
The evidence says it's possibly effective for athletic performance — that's the strongest rating we have for this ingredient. Whether that translates to noticeable results for you depends on your goals and how you use it, so talk with your doctor about whether it makes sense to try.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against use during pregnancy and while breastfeeding because there isn't enough data to know if it's safe. If you're in either situation and want to consider ornithine, talk with your doctor or pharmacist for personalized advice.
What about long-term use — is it safe to take every day for months?
Long-term safety hasn't been well studied, so we don't have solid data on that. Stick with your doctor or pharmacist on how long you should take it and whether periodic breaks make sense for you.
Does this help with insomnia or dry skin?
The evidence for both isn't established yet — we don't have enough data to say whether ornithine helps or not. If you're considering it for either of those, your doctor is the best person to discuss whether it's worth trying.
Are there any side effects I should watch for?
We don't have adverse effects documented in the data we hold. That doesn't mean none occur, but it does mean serious reactions aren't commonly reported. If you notice anything unusual after starting, let your doctor or pharmacist know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Ornithine HCL is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Ornithine HCL label
Go deeper

The Full Monographs Behind L-Ornithine HCL’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Ornithine HCL's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ornithine 1 reference
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the Ornithine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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