No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Ornithine L-Aspartate Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

L-Ornithine L-Aspartate is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for liver-related brain symptoms (hepatic encephalopathy), lowering blood ammonia levels, support in cirrhosis and fatty liver.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Ornithine L-Aspartate by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains one active ingredient: L-ornithine L-aspartate, an amino acid compound. It's been studied mainly for hepatic encephalopathy (a brain condition that can happen with severe liver disease), where the evidence suggests it may help.

The product contains no other inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded L-ornithine-l-aspartate's overall clinical evidence instead.

Moderate

Some clinical evidence supports L-ornithine-l-aspartate for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Hepatic encephalopathy — rated "Possibly Effective" (Natural Medicines).

The evidence for L-ornithine L-aspartate is strongest for hepatic encephalopathy, where it's rated possibly effective. For athletic performance, cachexia (muscle wasting), cirrhosis, and wound healing, the evidence isn't reliable enough yet to rate it — meaning either studies are too small, too few, or the results are mixed.

If you're considering this for one of those other uses, talk to your doctor about what the current science actually supports.

The evidence, ingredient by ingredient L-ornithine-l-aspartate

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth or given intravenously, L-ornithine L-aspartate is generally well tolerated. The most common side effects from IV infusion include cough, muscle cramps, nausea, vomiting, and less often diarrhea — slowing the infusion rate can help prevent nausea and vomiting.

Don't self-treat serious liver disease with this supplement; it's meant to be used under medical supervision. Safety data in pregnancy advises against use unless your doctor directs otherwise.

During breastfeeding, there isn't enough safety information, so avoid it unless your doctor advises you to take it. Talk with your doctor or pharmacist about whether this is right for you before starting.

Side effects, ingredient by ingredient L-ornithine-l-aspartate

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-ornithine L-aspartate. Still, because this product is primarily used for liver disease, your own doctor or pharmacist should review your full medication list to make sure it fits your health picture.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

L-ornithine L-aspartate may have a role for hepatic encephalopathy under medical care, but evidence for other uses is thin. Because serious liver disease needs professional oversight, this isn't a product to dose yourself for at home.

If you're pregnant, breastfeeding, or have liver problems, check with your doctor or pharmacist before taking it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Ornithine L-Aspartate, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X0023JWXQB
Net contents 500 Gram(s); 17.6 oz
Market status On market
Date entered into DSLD Sep 24, 2021
DSLD ID 254683
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Ornithine L-Aspartate by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Gram(s)
Maximum serving Sizes:
3 Gram(s)
Servings per container
167
UPC/BARCODE
X0023JWXQB
IngredientAmount% DV
L-Ornithine L-Aspartate3 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & pure bulk supplements

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 3 g (about 1/2 tbsp) once or twice daily with water, or as directed by a physician.

Storage

Store in a dry, cool place

See for yourself

L-Ornithine L-Aspartate by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Ornithine L-Aspartate by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Gram(s) Dosage formPowder Servings per container167 Amounts shown are per serving.

L-Ornithine L-Aspartate

No known
interactions
3 Gram(s) per serving

L-ornithine-L-aspartate (LOLA) is a combination of two amino acids studied mainly for lowering ammonia in people with liver disease and helping manage...

L-Ornithine L-Aspartate monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Ornithine L-Aspartate by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Ornithine L-Aspartate. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Ornithine L-Aspartate, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

L-Ornithine L-Aspartate by BulkSupplements.com: Common Questions

Does L-Ornithine L-Aspartate by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Ornithine L-Aspartate. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Ornithine L-Aspartate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is L-ornithine L-aspartate safe to take if I'm pregnant?
Safety hasn't been established in pregnancy, so the data advises against it unless your doctor directs otherwise. Talk with your doctor before taking it if you're pregnant or planning to be.
Can I take this while breastfeeding?
There isn't enough safety information during breastfeeding. Avoid it unless your doctor advises you to take it — ask your doctor or pharmacist whether it's okay for you.
What are the most common side effects?
When given intravenously, cough, muscle cramps, nausea, and vomiting are the most common. When taken by mouth, it's generally well tolerated. If you experience nausea, talk to your doctor about adjusting the dose or form.
Does L-ornithine L-aspartate really work for athletic performance?
The evidence isn't reliable enough yet to say. There isn't solid proof it helps with athletic performance, so don't expect it as a sports supplement based on current data.
Can I use this to self-treat liver disease at home?
No — serious liver disease needs medical supervision. This supplement is meant to be used under a doctor's care, not on your own. If you have liver problems, talk with your doctor about whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Ornithine L-Aspartate is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Ornithine L-Aspartate label
Go deeper

The Full Monographs Behind L-Ornithine L-Aspartate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Ornithine L-Aspartate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-ornithine-l-aspartate 3 references
  1. Ahmad, I., Khan, A. A., Alam, A., Dilshad, A., Butt, A. K., Shafqat, F., Malik, K., and Sarwar, S. L-ornithine-L-aspartate infusion efficacy in hepatic encephalopathy. J.Coll.Physicians Surg.Pak. 2008;18(11):684-687.
  2. Waghray A, Waghray N, Mullen K. Management of covert hepatic encephalopathy. J Clin Exp Hepatol 2015;5:S75-81. PubMed
  3. Pérez Hernández JL, Higuera de la Tijera F, Serralde-Zúñiga AE, Abdo Francis JM. Critical analysis of studies evaluating the efficacy of infusion of L-ornithine L-aspartate in clinical hepatic encephalopathy in patients with liver failure. Ann Hepatol 201

See these in context on the L-ornithine-l-aspartate monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring