No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Proline 2000 mg Capsules Ingredients & Drug Interactions

by BulkSupplements.com

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Proline 2000 mg Capsules is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Proline 2000 mg Capsules by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-proline, an amino acid (a building block of protein) at 2000 mg per capsule. The capsule itself is made from gelatin, an inactive ingredient that holds the powder together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Proline's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: joint and connective tissue support.
  • We looked for evidence on: Athletic performance, Fractures, Osteopenia, Osteoporosis, Wound healing, Collagen synthesis — and 1 related terms.
  • The closest evidence on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis, Fractures, Wound healing, Osteopenia.

The evidence for L-proline is currently insufficient to rate. The product label lists potential uses — athletic performance, osteoporosis, fractures, wound healing, and osteopenia (low bone density) — but we don't have reliable data showing it works for any of them at supplemental doses.

If you're considering it for a specific reason, talk with your doctor about whether the current evidence supports a trial.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-proline from food is generally considered low-risk, but supplement safety at higher doses hasn't been well studied. There isn't enough reliable data on supplemental doses to recommend them without a doctor's guidance — it's best to avoid extra amounts unless your doctor specifically advises it.

Safety while breastfeeding is also not established, so use caution if you're nursing.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-proline with any medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

L-proline is a single-ingredient amino acid supplement with no documented drug interactions. However, the evidence for its effectiveness at supplemental doses is currently insufficient to support its use.

If you're thinking about taking it for a specific health goal, check with your doctor first — and if you're pregnant or breastfeeding, talk with your pharmacist or doctor about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Proline 2000 mg Capsules, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003HYILTT
Net contents 240 Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 312923
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Proline 2000 mg Capsules by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
60
UPC/BARCODE
X003HYILTT
IngredientAmount% DV
L-Proline2000 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

L-Proline Capsules 2000 mg per serving

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 4 capsules once daily, or as directed by a physician.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Always consult a physician before taking any dietary supplement.

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Precautions

Keep out of reach of children.

Storage

Store in a dry, cool place

General Statements

New Scan Me

See for yourself

L-Proline 2000 mg Capsules by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Proline 2000 mg Capsules by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

L-Proline

No known
interactions
2000 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Proline 2000 mg Capsules by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Proline 2000 mg Capsules. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Proline 2000 mg Capsules, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

L-Proline 2000 mg Capsules by BulkSupplements.com: Common Questions

Does L-Proline 2000 mg Capsules by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Proline 2000 mg Capsules. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Proline 2000 mg Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-proline and what's it supposed to do?
L-proline is an amino acid — one of the building blocks your body uses to make protein. This product is marketed for athletic performance, bone health, and wound healing, but the evidence for it at supplemental doses isn't established yet.
Is it safe to take while I'm pregnant?
We don't have enough reliable data on supplemental L-proline during pregnancy to say either way. Talk with your doctor or pharmacist about whether it's right for you in your situation.
Is it safe while breastfeeding?
Safety during breastfeeding isn't established. Use caution and check with your doctor or pharmacist before starting it while nursing.
Does it have any side effects?
No adverse effects are documented in our data, but supplement safety at high doses hasn't been well studied. If you notice anything unusual after taking it, let your pharmacist know.
Can I just take this without checking with my doctor?
Because there isn't enough reliable data on supplemental doses, it's best not to take extra amounts unless your doctor advises it. Check with them first, especially if you have any health conditions or are taking other supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Proline 2000 mg Capsules is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Proline 2000 mg Capsules label
Go deeper

The Full Monographs Behind L-Proline 2000 mg Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Proline 2000 mg Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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