No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Proline 500 mg Ingredients & Drug Interactions

by AN Amazing Nutrition Amazing Formulas

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Proline 500 mg is a dietary supplement by AN Amazing Nutrition Amazing Formulas with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Proline 500 mg by AN Amazing Nutrition Amazing Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: L-proline, an amino acid that your body uses to build and repair connective tissue like collagen in skin, tendons, and cartilage. You get 500 mg per capsule.

The remaining ingredients — rice flour, microcrystalline cellulose, magnesium stearate, and gelatin — are inactive components that help form and deliver the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Proline's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports joint health and collagen production.
  • We looked for evidence on: Osteoporosis, Osteopenia, Fractures, Wound healing, connective tissue integrity, ligament and tendon health.
  • The closest evidence on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis (Natural Medicines).
  • Also on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Fractures, Wound healing, Osteopenia.

The evidence on L-proline for athletic performance, bone health (osteoporosis, osteopenia, fractures), and wound healing is insufficient — meaning the data we have doesn't establish that it works for any of these purposes. That doesn't mean it's ineffective; it means reliable studies haven't yet shown a clear benefit.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-proline comes naturally in food and is generally well tolerated from dietary sources, but the safety of supplemental doses hasn't been well studied. The data we hold advises caution: there isn't enough reliable information on supplemental amounts to say they're safe, so it's best to avoid extra doses unless your doctor recommends them.

Safety during breastfeeding is also not established, so talk with your doctor or pharmacist if you're nursing before starting this supplement.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for L-proline in our data. You're clear on the medication front, though as always, your own pharmacist can confirm there are no surprises with your specific prescriptions.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

L-Proline 500 mg is a single-ingredient amino acid supplement with no documented medication interactions. The evidence for it doesn't yet show it works for athletic performance, bone strength, or wound healing.

If you're pregnant or breastfeeding, or if you have questions about whether supplemental doses are right for you, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Proline 500 mg, straight from the product label.

Brand AN Amazing Nutrition Amazing Formulas
Barcode (UPC) 810180024471
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 251947
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Proline 500 mg by AN Amazing Nutrition Amazing Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
810180024471
IngredientAmount% DV
L-Proline500 mg--

Other ingredients: Rice Flour, Microcrystalline Cellulose, Magnesium Stearate, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

We believe that Amazing Nutrition is the key for healthy living. We are passionate about bringing you the finest selection of products which can perfectly complement a healthy diet and active lifestyle.

Formulation

L-Proline is an amino acid that is essential for the synthesis of collagen. Collagen is the main structural protein that constitutes all human connective tissues, including skin, tendons, ligaments, joints, bone, veins and arteries. L-Proline therefore provides the building blocks that help to stabilize and strengthen the structural components of the body.

Supports joint health Supports collagen production Promotes structural support

Contains No: Shellfish, egg, fish, peanuts, milk, soy, tree nuts or wheat.

Precautions

Keep out of reach of children

Do not use if safety seal is damaged or missing

Caution: If you are pregnant or nursing, taking medications or or have a medical condition, consult your doctor before using this product.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Storage

Store in a cool, dry place

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to cure, prevent, treat or diagnose any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in USA GMP Good Manufacturing Practice Quality Product

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take one (1) capsule daily with meals or as directed by a health care professional.

See for yourself

L-Proline 500 mg by AN Amazing Nutrition Amazing Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Proline 500 mg by AN Amazing Nutrition Amazing Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

L-Proline

No known
interactions
500 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: Rice Flour, Microcrystalline Cellulose, Magnesium Stearate, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Proline 500 mg by AN Amazing Nutrition Amazing Formulas Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Proline 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Proline 500 mg, from the product label.

AN Amazing Nutrition Amazing Formulas

See all AN Amazing Nutrition Amazing Formulas products
Name
Amazing Nutrition
City
Jersey City
State
NJ
Phone Number
1-800-526-0177
Web Address
www.amazingnutrition.com
Pharmacist Counseling Corner

L-Proline 500 mg by AN Amazing Nutrition Amazing Formulas: Common Questions

Does L-Proline 500 mg by AN Amazing Nutrition Amazing Formulas interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Proline 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Proline 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does L-proline actually help with wound healing or stronger bones?
The evidence isn't established yet. Studies haven't shown a clear benefit for wound healing, osteoporosis, fractures, or osteopenia — so we can't say whether it works for these.
Is this safe to take if I'm pregnant?
There isn't enough data to know either way. Talk with your doctor or pharmacist before taking it if you're pregnant — they can give you advice based on your situation.
Can I take this while breastfeeding?
Safety during breastfeeding is not established. Use caution and check with your doctor or pharmacist first if you're nursing.
What is L-proline and what does it do in the body?
L-proline is an amino acid — one of the building blocks your body uses to make and repair connective tissues like collagen in skin, tendons, and cartilage.
Are there any side effects listed for this supplement?
The data we have doesn't document side effects from L-proline supplementation, though supplement safety at these doses hasn't been well studied overall.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Proline 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Proline 500 mg label
Go deeper

The Full Monographs Behind L-Proline 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Proline 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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