L-Serine 2000 mg Ingredients & Drug Interactions
by SuperSmart
What is this page for?
First and foremost: checking L-Serine 2000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Serine 2000 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for memory and brain health, nervous system disorders (e.g., als research), mood and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of L-Serine 2000 mg by SuperSmart
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: L-serine, an amino acid your body uses to build proteins and support nerve function. The tablet also contains acacia gum as an inactive ingredient (a natural binder).
Does it work?
Not established
The evidence is mixed. L-serine is rated possibly effective for schizophrenia.
For Alzheimer's disease, ALS (amyotrophic lateral sclerosis or Lou Gehrig's disease), back pain, PTSD, and cognitive function, the reliable evidence isn't there yet — the data we hold shows insufficient information to rate it either way.
How safe is it?
Well-documented data
L-serine is generally well tolerated at the doses used in studies. The most common side effects are stomach-related: abdominal pain, bloating, indigestion, loss of appetite, and nausea — and they tend to increase with higher doses.
At very high doses (greater than 25 grams daily), rare serious effects like seizures and reversible eye movement problems have been reported. Don't use this supplement in pregnancy or while breastfeeding.
The safety data isn't there, so the advice is to avoid it unless your doctor tells you otherwise. Long-term safety with supplements hasn't been well established, so check in with your pharmacist or doctor if you're planning to take this regularly.
Meds to double-check
No known interactions
No interactions are documented for L-serine in our data.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
This supplement might be worth considering if you have schizophrenia and want to explore it with your doctor — that's where the evidence is strongest. For other conditions, the proof isn't solid yet.
Anyone pregnant or breastfeeding should skip it. Talk to your pharmacist before starting, especially if you have a history of seizures or digestive issues.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Serine 2000 mg, straight from the product label.
| Brand | SuperSmart |
|---|---|
| Barcode (UPC) | 5453003828044 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2025 |
| DSLD ID | 332385 |
| Product type | Amino Acid/protein |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Serine 2000 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Formula
L-serine 2000 mg Per Day
Each tablet contains 1000 mg of L-serine.
Suggested/Recommended/Usage/Directions
Recommended use: Adults. Take 2 tablets a day.
Precautions
Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.
Keep out of childrens' reach.
As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.
Storage
Store away from direct light, heat and humidity.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Serine 2000 mg by SuperSmart label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Serine 2000 mg by SuperSmart
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
L-Serine
No knowninteractions
Serine is an amino acid your body can make on its own and also gets from protein-rich foods, so most people do not need a supplement. L-serine has bee...
L-Serine monograph & interactionsOther (inactive) ingredients: Acacia Gum. These complete the product’s ingredient list but are not active constituents.
L-Serine 2000 mg by SuperSmart Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in L-Serine 2000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for L-Serine 2000 mg, from the product label.
SuperSmart
See all SuperSmart products- Name
- SN Worldwide Unipessoal, LDA
- Street Address
- Avenida Do Infante 66 Edificio Quinta Avenida 1 C
- City
- Funchal
- ZipCode
- 9000-015
L-Serine 2000 mg by SuperSmart: Common Questions
Does L-Serine 2000 mg by SuperSmart interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is L-serine, and what does it do in my body?
Will this help my memory or thinking?
What side effects should I watch for?
Is it safe to take long-term?
Can I take this if I'm pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Serine 2000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Serine 2000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Serine 2000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Serine 3 references
- Fridman V, Suriyanarayanan S, Novak P, et al. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019;92(4):e359-e370.
- Kantrowitz JT, Malhotra AK, Cornblatt B, et al. High dose D-serine in the treatment of schizophrenia. Schizophr Res. 2010 Aug;121(1-3):125-30. PubMed
- Levine TD, Miller RG, Bradley WG, et al. Phase I clinical trial of safety of L-serine for ALS patients. Amyotroph Lateral Scler Frontotemporal Degener. 2017;18(1-2):107-111. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC