No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Serine Unflavored Ingredients & Drug Interactions

by California Gold Nutrition

Powder Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Serine Unflavored is a dietary supplement by California Gold Nutrition with 1 active ingredient. Its ingredients are commonly taken for memory and brain health, nervous system disorders (e.g., als research), mood and stress support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Serine Unflavored by California Gold Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-serine, a naturally occurring amino acid. L-serine plays a role in nerve cell function and is found in small amounts in foods like eggs, dairy, and meat.

This unflavored powder lets you mix it into beverages or foods without added flavor or sweeteners.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Serine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Serine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

The evidence supporting L-serine is mixed and sparse. It's rated possibly effective for schizophrenia, meaning some research suggests it may help, but more study is needed.

For Alzheimer disease, ALS (Lou Gehrig's disease), back pain, PTSD, and general cognitive function, the evidence isn't reliable enough to rate it — we simply don't have solid data one way or the other.

The evidence, ingredient by ingredient Serine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-serine at food amounts is generally well tolerated, but the long-term safety of supplement doses isn't well established. At medicinal doses, gastrointestinal upset — nausea, bloating, abdominal pain, indigestion, and loss of appetite — is the most common side effect and appears to depend on how much you take.

Seizures are rare but have been reported at very high doses (over 25 grams daily). There isn't enough safety data to use L-serine supplements during pregnancy, so the recommendation is to avoid it unless your doctor advises otherwise.

Safety during breastfeeding hasn't been studied, so it's best avoided unless directed by your doctor.

Side effects, ingredient by ingredient Serine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for L-serine. Before you start, check with your own doctor or pharmacist to confirm it won't interfere with your specific medications.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

L-serine may be worth considering if you're exploring options for schizophrenia, though the evidence is still developing. If you're pregnant, breastfeeding, or taking any medications, talk it over with your doctor or pharmacist first — they can assess whether it fits your individual situation and flag any concerns we might not have data on yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Serine Unflavored, straight from the product label.

Brand California Gold Nutrition
Barcode (UPC) 898220015085
Net contents 2.2 lb(s); 1 KG(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 274249
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Serine Unflavored by California Gold Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Gram(s)
Maximum serving Sizes:
10 Gram(s)
Servings per container
100
UPC/BARCODE
898220015085
IngredientAmount% DV
L-Serine10 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Mix 1 scoop (approximately 10 grams) in juice or beverage of your choice 1 to 3 times per day. Best when taken as directed by a qualified healthcare professional.

Precautions

Warnings: Keep out of reach of children.

Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.

Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.

Sealed for your protection. Do not use if seal is missing or broken.

This product is not manufactured with eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

Storage

Best stored at controlled room temperature 20 degrees C to 25 degrees C (68 degrees F to 77 degrees F). Improper storage conditions, such as extended exposure to direct sunlight, high heat & humidity can cause product degradation over time.

FDA Disclaimer Statement

This statement has not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

L-Serine Amino Acid AjiPure Amino Acids

Formulation

Formulated to Contain No gluten No GMOs No soy

This product is not manufactured with eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, or gluten.

FDA Statement of Identity

Dietary Supplement

General Statements

10 grams per 1 slightly rounded scoop is an average. Individual scooping technique may yield slightly less than or slightly more than 10 grams. Slightly rounded scoop 13cc Image not actual scoop size

Brand IP Statement(s)

AjiPure is a registered trademark of AJINOMOTO CO., INC.

See for yourself

L-Serine Unflavored by California Gold Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Serine Unflavored by California Gold Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size10 Gram(s) Dosage formPowder Servings per container100 Amounts shown are per serving.

L-Serine

No known
interactions
10 Gram(s) per serving

Serine is an amino acid your body can make on its own and also gets from protein-rich foods, so most people do not need a supplement. L-serine has bee...

L-Serine monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Serine Unflavored by California Gold Nutrition Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Serine Unflavored. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Serine Unflavored, from the product label.

California Gold Nutrition

See all California Gold Nutrition products
Name
California Gold Nutrition
Street Address
22780 Harley Knox Blvd.
City
Perris
State
CA
ZipCode
92570
Web Address
www.calgn.com
Pharmacist Counseling Corner

L-Serine Unflavored by California Gold Nutrition: Common Questions

Does L-Serine Unflavored by California Gold Nutrition interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Serine Unflavored. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Serine Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
Stomach upset is most common — nausea, bloating, belly pain, indigestion, and loss of appetite. These tend to happen at higher doses. At very high doses (over 25 grams daily), seizures have been reported, though this is rare.
Can I take this while pregnant?
There isn't enough safety data on L-serine supplements during pregnancy. The recommendation is to avoid it unless your doctor specifically advises you to take it.
Is it safe to breastfeed while taking L-serine?
Safety during breastfeeding hasn't been studied. It's best to avoid supplements unless your doctor directs you to use one.
Does L-serine really improve memory or thinking?
We don't have reliable evidence on that yet. For general cognitive function, back pain, PTSD, and Alzheimer disease, the research isn't strong enough to rate it one way or the other.
What is L-serine, and where does it come from?
It's an amino acid — a building block your body uses to make proteins and support nerve cells. You get small amounts naturally from foods like eggs, dairy, and meat; this product gives you more in supplement form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Serine Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Serine Unflavored label
Go deeper

The Full Monographs Behind L-Serine Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Serine Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Serine 3 references
  1. Fridman V, Suriyanarayanan S, Novak P, et al. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019;92(4):e359-e370.
  2. Kantrowitz JT, Malhotra AK, Cornblatt B, et al. High dose D-serine in the treatment of schizophrenia. Schizophr Res. 2010 Aug;121(1-3):125-30. PubMed
  3. Levine TD, Miller RG, Bradley WG, et al. Phase I clinical trial of safety of L-serine for ALS patients. Amyotroph Lateral Scler Frontotemporal Degener. 2017;18(1-2):107-111. PubMed

See these in context on the Serine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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