Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Prenatal DHA Ingredients & Drug Interactions

by California Gold Nutrition

Softgel Capsule Category: Other Combinations
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Prenatal DHA is a dietary supplement by California Gold Nutrition with 3 active ingredients. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 27 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Prenatal DHA by California Gold Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (1,240 mg) without saying how much of each component you get.
  • “Choline” is listed as a grouped ingredient — the label gives one combined amount (60 mg) without saying how much of each component you get.

This prenatal supplement contains three active ingredients. Two are omega-3 fatty acids — eicosapentaenoic acid and docosahexaenoic acid — which are the key components of fish oil.

The third is alpha-glycerophosphocholine (alpha-GPC), a compound derived from phospholipids that supports brain health. The remaining ingredients are inactive carriers and stabilizers, including fish gelatin, glycerin, and other plant-derived compounds.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Brain and prenatal nutrition for fetal development.
  • We looked for evidence on: Infant development, Neural tube birth defects, Maternal nutrition, Fetal brain development.
  • The closest evidence on file: Alpha-gpc is rated "Insufficient Reliable Evidence To Rate" for Brain tumor (Natural Medicines).

Alpha-GPC has possibly effective evidence for Alzheimer disease. For other conditions this product may target — brain tumors, cognitive function, vascular dementia, and stroke — the evidence we hold is insufficient to rate its benefit.

We hold no effectiveness data in our records for the omega-3 fatty acids in this product, so we cannot comment on their established benefits.

The evidence, ingredient by ingredient Choline Alpha-gpc

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha-GPC is generally well tolerated in studies, though long-term safety isn't fully established. Rarely, people taking it orally have reported dizziness, headache, insomnia, nausea, heartburn, and diarrhea.

Very rarely, oral use for at least 2 months has been associated with an elevated stroke risk compared with non-users or shorter-term users. We hold no pregnancy and lactation safety data for any ingredient in this product — talk with your doctor or pharmacist before taking it while pregnant or breastfeeding.

Side effects, ingredient by ingredient Choline Alpha-gpc

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Alpha-gpc.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take scopolamine (the motion sickness patch, Transderm Scop), alpha-GPC might weaken its effects. Check all your medications with the tool below, particularly because we couldn't verify the omega-3 ingredients in this product for drug interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is a prenatal omega-3 plus alpha-GPC formula. If you're pregnant, planning pregnancy, or breastfeeding, discuss it with your doctor or pharmacist first, since we don't have safety data for these ingredients in those settings.

Before you start, especially if you take any medications, check them against the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prenatal DHA, straight from the product label.

Brand California Gold Nutrition
Barcode (UPC) 898220013364
Net contents 60 Fish Gelatin Softgel(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 299676
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Pregnant Women, Lactating, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prenatal DHA by California Gold Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Pregnant and Lactating
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
898220013364
IngredientAmount% DV
Calories25 Calorie(s)--
Eicosapentaenoic Acid120 mg--
Docosahexaenoic Acid900 mg--
Total Omega-3 Fatty Acids1240 mg--
Cholesterol10 mg3%
Total Fat2 Gram(s)3%
Choline60 mg11%
Alpha-Glycerophosphocholine150 mg--

Other ingredients: Omega-3 Fatty Acids, Fish Gelatin, Glycerin, Water, Purified, Annatto Extract, Carob, Beeswax, Soy Lecithin, Mixed Tocopherols

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 softgels daily, with food. Best when taken as directed by a qualified healthcare professional.

Precautions

Warnings: Keep out of reach of children.

Consult with a licensed physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements. Sealed for protection. Do not use if seal is missing or broken.

Contains: Fish (Anchovy, Sardine, and Mackerel [Fish Oil], Catfish and Tilapia [Fish Gelatin]) and Soy

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

Storage

Best stored at controlled room temperature 20 degrees C to 25 degrees C (68 degrees F to 77 degrees F). Improper storage conditions, such as extended exposure to direct sunlight, high heat & humidity can cause product degradation over time.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

KD-Pur is a trademark of KD Pharma. California Gold Nutrition is a registered trademark of Madre Labs, LLC

Formula

For pregnant & nursing mothers

Formulation

KD-Pur

Supports prenatal health

Formulated to contain No Gluten No GMOs

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat or gluten.

FDA Statement of Identity

Dietary Supplement

See for yourself

Prenatal DHA by California Gold Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Prenatal DHA by California Gold Nutrition

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Total Omega-3 Fatty Acids

1240 mg per serving
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid

Choline

Interacts with
16 drugs
60 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Other (inactive) ingredients: Omega-3 Fatty Acids, Fish Gelatin, Glycerin, Water, Purified, Annatto Extract, Carob, Beeswax, Soy Lecithin, Mixed Tocopherols. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prenatal DHA by California Gold Nutrition Drug Interactions

Want to check YOUR meds against Prenatal DHA?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
27Drugs
27 Minor

Ingredients driving the most interactions

Choline 16

Each ingredient & the kinds of drugs it affects

For each ingredient in Prenatal DHA with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Prenatal DHA, from the product label.

California Gold Nutrition

See all California Gold Nutrition products
Name
Madre Labs, LLC
Street Address
301 N. Lake Ave. #500
City
Pasadena
State
CA
ZipCode
91101
Web Address
www.calgn.com
Pharmacist Counseling Corner

Prenatal DHA by California Gold Nutrition: Common Questions

Does Prenatal DHA by California Gold Nutrition interact with any medications?
Yes. Based on its ingredients, Prenatal DHA has a known interaction with 27 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prenatal DHA contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
We don't have safety data on file for any of the ingredients in this product during pregnancy. Talk with your doctor or pharmacist before starting — they can give you personalized advice based on your health and what you're already taking.
What is alpha-GPC, and what does it do?
Alpha-GPC is a compound that supports brain health. We have evidence it may help with Alzheimer disease, but for other brain-related benefits, the evidence isn't yet established in our data.
Does this product have side effects?
Alpha-GPC is generally well tolerated, though rarely people report dizziness, headache, insomnia, nausea, or digestive upset. Very rarely, long-term use (2+ months) has been linked to an elevated stroke risk — discuss that with your doctor if you're considering longer-term use.
Why does this say I can't check the omega-3 fatty acids for interactions?
We don't hold interaction data for the eicosapentaenoic and docosahexaenoic acids in our database, so we can't verify whether they interact with your medications. That doesn't mean they're unsafe — it means we haven't checked them. Your pharmacist can help clarify.
Can I take this if I use a scopolamine patch for motion sickness?
Alpha-GPC in this product may weaken the scopolamine patch's effects. Check with your pharmacist or doctor before combining them — they can advise whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prenatal DHA is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prenatal DHA label
Sources

Sources & How We Checked

Prenatal DHA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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