No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lactase Enzyme 125 mg Ingredients & Drug Interactions

by The Vitamin Shoppe

Softgel Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lactase Enzyme 125 mg is a dietary supplement by The Vitamin Shoppe with 1 active ingredient. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lactase Enzyme 125 mg by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lactase, an enzyme that breaks down lactose (the natural sugar in milk and dairy). If your body doesn't make enough lactase on its own — which is what happens with lactose intolerance — taking it as a supplement lets you digest dairy without the bloating, gas, or cramping.

The softgel also contains several inactive ingredients (soybean oil, gelatin, glycerin, purified water, yellow beeswax, soy lecithin, titanium dioxide, and sorbitol crystalline powder) that help deliver and protect the enzyme.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: lactose intolerance enzyme support.
  • We looked for evidence on: Lactose intolerance, dairy digestion, milk tolerance.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase is effective for lactose intolerance — meaning it actually does help you digest dairy when your own enzyme production falls short. The evidence for its use in premature infant colic and related conditions is insufficient, so we can't say whether it works for those purposes based on the data we hold.

The evidence, ingredient by ingredient Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated when used as directed. A rare case of allergic reaction (contact dermatitis and nasal and eye symptoms) was reported in a worker exposed to powdered lactase, but this is not typical and usually doesn't occur in people taking the supplement normally.

For pregnancy and breastfeeding, the safety data indicates it's likely safe. However, because the data on regular use during pregnancy is limited, talk with your doctor before using it regularly if you're pregnant.

Similarly, since lactase acts only in the gut and isn't absorbed, the data suggests it should be fine while nursing, but ask your doctor or pharmacist first to be sure it fits your individual situation.

Side effects, ingredient by ingredient Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for lactase in our data. Because it works only in your digestive tract and isn't absorbed into your bloodstream, it's not expected to affect how your medications work.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're lactose intolerant, this enzyme can help you enjoy dairy without the uncomfortable side effects. It won't interact with your medications since it stays in your digestive system.

Before starting it regularly — especially if you're pregnant or nursing — check in with your doctor or pharmacist to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactase Enzyme 125 mg, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536015245
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 245286
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactase Enzyme 125 mg by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
100
UPC/BARCODE
766536015245
IngredientAmount% DV
Lactase125 mg--

Other ingredients: Soybean Oil, Gelatin, Glycerin, purified Water, yellow Beeswax, Soy Lecithin, Titanium Dioxide, Sorbitol crystalline powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Specialty

Gluten-free Dairy-free Nut-free

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Quality Promise Tested & Trusted

Precautions

Contains: Soy.

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Suggested/Recommended/Usage/Directions

Directions: Take one (1) softgel up to three (3) times daily, just before eating a meal, food or drink containing lactose.

Storage

Store in a cool, dry place.

See for yourself

Lactase Enzyme 125 mg by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lactase Enzyme 125 mg by The Vitamin Shoppe

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.

Lactase

No known
interactions
125 mg per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Purified Water, Yellow Beeswax, Soy Lecithin, Titanium Dioxide, Sorbitol crystalline powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactase Enzyme 125 mg by The Vitamin Shoppe Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lactase Enzyme 125 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lactase Enzyme 125 mg, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
The Vitamin Shoppe
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-866-293-3367
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Lactase Enzyme 125 mg by The Vitamin Shoppe: Common Questions

Does Lactase Enzyme 125 mg by The Vitamin Shoppe interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lactase Enzyme 125 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lactase Enzyme 125 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lactase actually work for lactose intolerance?
Yes — lactase is effective for lactose intolerance. It breaks down lactose in dairy so your body can digest it without bloating, gas, or cramping.
Can I take this while pregnant?
The data shows it's likely safe, but because regular use during pregnancy hasn't been studied extensively, talk with your doctor before taking it regularly if you're pregnant. They know your full medical picture and can give you personalized advice.
Is it safe while breastfeeding?
Limited data suggests it's probably okay since lactase stays in your gut and isn't absorbed into your bloodstream — so it shouldn't reach your breast milk. Ask your doctor or pharmacist first to be confident it's right for you.
Can I have an allergic reaction to lactase?
It's very rare, but one case of allergic reaction (including contact dermatitis and nasal and eye symptoms) was reported in someone exposed to powdered lactase. This is not typical and usually doesn't happen to people taking the supplement normally.
Will this help with colic in babies?
We don't have enough reliable evidence to say whether lactase helps with infant colic. Talk with your pediatrician about what might work for your baby.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactase Enzyme 125 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactase Enzyme 125 mg label
Go deeper

The Full Monographs Behind Lactase Enzyme 125 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lactase Enzyme 125 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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