Phosphatidyl Choline 385 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Phosphatidyl Choline 385 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phosphatidyl Choline 385 mg is a dietary supplement by The Vitamin Shoppe with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Phosphatidyl Choline 385 mg by The Vitamin Shoppe
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: phosphatidylcholine, a fatty compound found naturally in cell membranes and foods like eggs and soy. It's delivered in a 385 mg softgel capsule with gelatin, glycerin, medium chain triglycerides, and purified water as inactive ingredients.
Does it work?
Not established
Phosphatidylcholine is possibly effective for ulcerative colitis (an inflammatory bowel condition). For nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence we hold is insufficient to rate whether it works.
Talk with your doctor about what the science shows for your specific reason for considering it.
How safe is it?
Well-documented data
Phosphatidylcholine is generally well tolerated. At the dose in this product, side effects are unlikely, but high doses can cause digestive upset — bloating, diarrhea, nausea, vomiting, and altered taste have been reported, as well as sweating and itching.
Choline (the active nutrient) is needed during pregnancy, but the safety of supplements beyond food sources isn't well studied. If you're pregnant or breastfeeding, check with your doctor or pharmacist before starting — there isn't enough data to know either way.
Meds to double-check
No known interactions
No interactions are documented in our data for phosphatidylcholine. That said, it's always smart to check your exact medications with the search tool on this page, or ask your pharmacist before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
Phosphatidyl Choline might interest you if you're looking into support for ulcerative colitis or liver health, though the evidence is mixed. It's generally well tolerated at normal doses.
Talk to your pharmacist if you're pregnant, breastfeeding, or have questions about whether it fits your health goals.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phosphatidyl Choline 385 mg, straight from the product label.
| Brand | The Vitamin Shoppe |
|---|---|
| Net contents | 100 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2017 |
| DSLD ID | 73889 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phosphatidyl Choline 385 mg by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Calories from Fat | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | -- |
| Phosphatidyl Choline | 385 mg | -- |
Other ingredients: Gelatin, Glycerin, Medium Chain Triglycerides, purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Contains soy
Precautions
Contains soy
Warning Keep out of reach of children.
General Statements
Natural food supplement
Essential for healthy liver function
Dietary Supplement
About this product One of the phospholipids found in high concentrations in the brain, reported in studies as being able to improve memory, learning, concentration, word recall, and mood in middle-aged and elderly persons with dementia or decreased cognitive function. Has been used to support memory and cognitive function in individuals with mild to moderate faulty memory due to age.
How do you read a supplement facts label?
Formulation
No; yeast, corn, wheat, sugar, salt, starch, dairy, citrus, fish
Does Not Contain: Yeast, corn, wheat, sugar, salt, starch, dairy, citrus, fish, preservatives, artificial colors or flavors added.
Suggested/Recommended/Usage/Directions
Directions As a dietary supplement, take one (1) to three (3) softgels daily, preferably with meals.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phosphatidyl Choline 385 mg by The Vitamin Shoppe label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phosphatidyl Choline 385 mg by The Vitamin Shoppe
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.
Phosphatidyl Choline
No knowninteractions
Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...
Phosphatidyl Choline monograph & interactionsOther (inactive) ingredients: Gelatin, Glycerin, Medium Chain Triglycerides, Purified Water. These complete the product’s ingredient list but are not active constituents.
Phosphatidyl Choline 385 mg by The Vitamin Shoppe Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Phosphatidyl Choline 385 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Phosphatidyl Choline 385 mg, from the product label.
The Vitamin Shoppe
See all The Vitamin Shoppe products- Name
- The Vitamin Shoppe
- Phone Number
- 1-866-293-3367
Phosphatidyl Choline 385 mg by The Vitamin Shoppe: Common Questions
Does Phosphatidyl Choline 385 mg by The Vitamin Shoppe interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is phosphatidylcholine and what does it do in my body?
Will this help my liver health?
Can I take this if I'm pregnant?
What side effects should I expect?
Does this interact with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phosphatidyl Choline 385 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phosphatidyl Choline 385 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Phosphatidyl Choline 385 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylcholine 15 references
- Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
- Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
- Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
- Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
- Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
- Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
- Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
- Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
- Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
- Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
- Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
- Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
- Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC