No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lactoferrin 250 mg Ingredients & Drug Interactions

by Best Naturals

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Lactoferrin 250 mg is a dietary supplement by Best Naturals with 1 active ingredient. Its ingredients are commonly taken for iron deficiency and anemia support, immune support, gut health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lactoferrin 250 mg by Best Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lactoferrin, an iron-binding protein that your body produces naturally and that also appears in breast milk. The capsule itself is made up of inactive ingredients — cellulose, magnesium stearate, silica, and microcrystalline cellulose — which are standard fillers and binders that help hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lactoferrin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: intestinal health and immune function support.
  • We looked for evidence on: Helicobacter pylori, Iron deficiency anemia, Respiratory tract infections, Acne, gut barrier function, immune response.
  • The closest evidence on file: Lactoferrin is rated "Insufficient Reliable Evidence To Rate" for Acne (Natural Medicines).
  • Also on file: Lactoferrin is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections, Helicobacter pylori, Iron deficiency anemia.

The evidence for lactoferrin is mixed depending on what you're taking it for. It's rated possibly effective for sepsis and for pregnancy-related iron deficiency.

However, it's rated likely ineffective for reducing fetal and premature infant mortality and for preventing necrotizing enterocolitis (a serious intestinal condition in preterm infants). If you're considering it for a specific condition, talk with your doctor about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Lactoferrin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactoferrin is generally well tolerated at typical doses, but long-term safety data of high quality are limited — most research has been short-term. At very high doses of 7.2 grams daily, some people report constipation, diarrhea, anorexia (loss of appetite), fatigue, and chills.

In newborns, rare cases of jaundice, bloody stool, bowel obstruction, and intestinal perforation have been reported in trials. For pregnancy, the safety data aren't fully established, so use only under medical supervision.

While lactoferrin occurs naturally in breast milk, the safety of supplements while breastfeeding hasn't been well studied — talk with your doctor or pharmacist about whether it's right for you if you're nursing.

Side effects, ingredient by ingredient Lactoferrin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for lactoferrin in the data we hold. This doesn't mean interactions are impossible — it means we don't have monograph data showing them.

If you're on any prescription medications, use the search tool on this page to check them individually for peace of mind.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Lactoferrin may be worth considering if you're exploring options for sepsis or pregnancy-related iron deficiency, though the evidence is promising but not conclusive. Because long-term safety data are limited and dosing matters (especially at higher amounts), this isn't a take-it-and-forget-it supplement.

Check with your own doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or have a newborn.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lactoferrin 250 mg, straight from the product label.

Brand Best Naturals
Barcode (UPC) 817716017501
Net contents 60 Veggie Cap(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 269782
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lactoferrin 250 mg by Best Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
817716017501
IngredientAmount% DV
Lactoferrin250 mg--

Other ingredients: Cellulose, Magnesium Stearate, Silica, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Certain research publicaions indicate that Lactoferrin may help support the following: Supports intestinal health. Promotes healthy immune function.

Precautions

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Storage

Keep in cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Made in USA

GMP Good Manufacturing Practice Product

Formulation

Premium formula

3rd party lab tested

No artificial color, flavor or sweetener, no preservatives, no sugar, no corn, no soy, no egg, no gluten, no wheat, no yeast, no fish. Sodium free.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule daily with food or as directed by a healthcare practitioner.

See for yourself

Lactoferrin 250 mg by Best Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lactoferrin 250 mg by Best Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Lactoferrin

No known
interactions
250 mg per serving

Lactoferrin is an iron-binding protein found naturally in milk and other body fluids, and supplements are usually made from cow's milk or rice. It is...

Lactoferrin monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Silica, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lactoferrin 250 mg by Best Naturals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lactoferrin 250 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lactoferrin 250 mg, from the product label.

Best Naturals

See all Best Naturals products
Name
Best Naturals
Street Address
PO Box 394
City
Kenilworth
State
NJ
ZipCode
07033
Phone Number
1-877-659-6004
Web Address
www.shopbestnaturals.com
Pharmacist Counseling Corner

Lactoferrin 250 mg by Best Naturals: Common Questions

Does Lactoferrin 250 mg by Best Naturals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lactoferrin 250 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lactoferrin 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does lactoferrin do?
Lactoferrin is a protein your body makes naturally and that's also found in breast milk. In supplement form, it's been studied for things like sepsis and pregnancy-related iron deficiency, though the evidence is still being worked out.
Is it safe to take lactoferrin long-term?
It's generally well tolerated at typical doses, but high-quality long-term safety data are limited. If you're thinking about taking it regularly over months or years, talk with your doctor about what the research actually shows for your specific reason.
Can I take this if I'm pregnant?
Lactoferrin is rated possibly safe in pregnancy, but the evidence isn't fully established. If you're pregnant and considering it, use it only under medical supervision — talk with your doctor or midwife first.
Is it okay to take while breastfeeding?
The safety of lactoferrin supplements while breastfeeding hasn't been well studied, even though the protein occurs naturally in breast milk. There isn't enough data to know either way, so check with your doctor or pharmacist for personalized advice.
What side effects might I notice?
At typical doses, side effects are uncommon. At very high doses (7.2 grams daily), some people report constipation, diarrhea, appetite loss, fatigue, and chills. Gastrointestinal effects tend to be milder with lactoferrin than with other iron sources like ferrous sulfate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lactoferrin 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lactoferrin 250 mg label
Go deeper

The Full Monographs Behind Lactoferrin 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lactoferrin 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactoferrin 6 references
  1. Food and Drug Administration, CFSAN/Office of Food Additive Safety. Agency Response Letter GRAS Notice No. GRN 000130. 2003. Available at: http://www.cfsan.fda.gov/~rdb/opa-g130.html (Accessed 29 June 2005).
  2. Okada S, Tanaka K, Sato T, et al. Dose-response trial of lactoferrin in patients with chronic hepatitis C. Jpn J Cancer Res 2002;93:1063-9. PubMed
  3. Abu Hashim H, Foda O, Ghayaty E. Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials. Eur J Obstet Gynecol Reprod Biol. 2017;219:45-52. PubMed
  4. Tarnow-Mordi WO, Abdel-Latif ME, Martin A, et al. The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Health. 2020 Jun PubMed
  5. ELFIN trial investigators group. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Lancet. 2019 Feb 2;393(10170):423-433. doi: 10.1016/S0140-6736(18)32221-9.
  6. Lepanto MS, Rosa L, Cutone A, Conte MP, Paesano R, Valenti P. Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: An interventional study. Front Immunol. 2018 Sep 21;9:2123. PubMed

See these in context on the Lactoferrin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring