Colostrum Plus With Lactoferrin Ingredients & Drug Interactions
by Symbiotics
What is this page for?
First and foremost: checking Colostrum Plus With Lactoferrin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Colostrum Plus With Lactoferrin is a dietary supplement by Symbiotics with 3 active ingredients. Its ingredients are commonly taken for iron deficiency and anemia support, immune support, gut health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Colostrum Plus With Lactoferrin by Symbiotics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: Lactoferrin and Immunoglobulins, plus Colostrum as a blend. Lactoferrin is a protein found naturally in milk and other body fluids; it plays a role in immune function and iron transport.
Immunoglobulins are antibodies that support immune response. The inactive ingredients — Medium Chain Triglycerides, Sunflower Lecithin, Silicon Dioxide, and HPMC — are fillers and capsule materials.
Does it work?
Moderate evidence
The evidence is mixed. Lactoferrin is possibly effective for sepsis and pregnancy-related iron deficiency.
However, it's rated likely ineffective for reducing fetal and premature infant mortality, and likely ineffective for preventing necrotizing enterocolitis (NEC), a serious intestinal condition in newborns. We don't have effectiveness data on file for Immunoglobulins or the overall colostrum blend.
How safe is it?
Well-documented data
Lactoferrin is generally well tolerated at typical doses, though long-term safety data are limited. The most common side effects at standard doses are mild gastrointestinal issues — diarrhea or constipation — but they're less frequent than with other iron supplements.
At much higher doses of 7.2 grams daily, you may see more constipation, loss of appetite, fatigue, and chills. In newborns, rare cases of jaundice, bloody stool, and bowel problems have been reported in trials.
For pregnancy, the safety data aren't fully established — use only under medical supervision. For breastfeeding, while Lactoferrin occurs naturally in breast milk, the safety of taking supplements hasn't been well studied.
We don't have safety data on file for Immunoglobulins.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check. Run your exact medications through the tool on this page to be sure.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product may be worth considering if you're interested in immune support or if your doctor has suggested Lactoferrin for sepsis or pregnancy-related iron deficiency. If you're pregnant, breastfeeding, or taking any medications, check with your pharmacist first.
Gastrointestinal side effects are possible at typical doses; stick to standard dosing to minimize them.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Colostrum Plus With Lactoferrin , straight from the product label.
| Brand | Symbiotics |
|---|---|
| Barcode (UPC) | 647303040052 |
| Net contents | 120 Veg Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 275845 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Colostrum Plus With Lactoferrin by Symbiotics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Protein | 1 Gram(s) | 1% |
| Lactoferrin | 30 mg | -- |
| Calories | 9 Calorie(s) | -- |
| Immunoglobulins | 232 mg | -- |
| Colostrum | 931 mg | -- |
Other ingredients: Medium Chain Triglycerides, Sunflower Lecithin, Silicon Dioxide, HPMC
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Immune Factors Fight back with Symbiotics Colostrum Plus with Immunoglobulins and Lactoferrin! Nature provides an immune defense network, but your immune system is challenged by normal physical and mental stress, as well as aging.
Under the Symbiotics label, Immunoglobulins (IgG) levels are verified by laboratory testing. Quality and Purity Assured. Our colostrum is sourced exclusively from the first milking of cows not treated with rBST at USDA Grade A Dairies. All colostrum is laboratory tested and verified free from pesticides and antibiotics.
Supports healthy immune response Supports normal GI tract health
Gluten free
Formula
Colostrum Plus with Immunoglobulins (IgG) and Lactoferrin powerfully enhances normal immune factors, providing dual action-in the bloodstream and in the GI tract. Contains three times the Lactoferrin as our regular Colostrum Plus capsules.
Now with 25% IgG Antibodies and Lactoferrin 30 mg
Precautions
Each bottle is double sealed for quality and safety. If either seal is broken or missing, do not use and call 1-800-421-1830.
Warning: If you have a physician-diagnosed health condition, consult your doctor before taking this product. Discontinue use if you experience adverse reactions and consult your doctor.
Contains: Milk
Storage
Close tightly and store in cool, dry place (below 75 degrees F), away from heat.
General Statements
The FDA has determined that there is no significant difference between cows treated with rBST and those not treated.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Symbiotics and Colostrum Plus are registered trademarks of Prevention, LLC. Nature's First Immune Defense is a trademark of Prevention, LLC
Symbiotics Nature's First Immune Defense
Copyright 2020 Prevention, LLC
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 2 capsules, twice daily, with water or your drink of choice, on empty stomach. Triple this amount in times of environmental or physical stress.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Colostrum Plus With Lactoferrin by Symbiotics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Colostrum Plus With Lactoferrin by Symbiotics
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Protein
Lactoferrin
No knowninteractions
Lactoferrin is an iron-binding protein found naturally in milk and other body fluids, and supplements are usually made from cow's milk or rice. It is...
Lactoferrin monograph & interactionsColostrum
- › Immunoglobulins
Other (inactive) ingredients: Medium Chain Triglycerides, Sunflower Lecithin, Silicon Dioxide, HPMC. These complete the product’s ingredient list but are not active constituents.
Colostrum Plus With Lactoferrin by Symbiotics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Colostrum Plus With Lactoferrin . This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Colostrum Plus With Lactoferrin , from the product label.
Symbiotics
See all Symbiotics products- Name
- Naturade a division of Prevention, LLC
- City
- Irvine
- State
- CA
- ZipCode
- 92614
- Phone Number
- 1-800-421-1830
- Web Address
- www.symbiotics.com
Colostrum Plus With Lactoferrin by Symbiotics: Common Questions
Does Colostrum Plus With Lactoferrin by Symbiotics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What exactly is Lactoferrin?
Can I take this while I'm pregnant?
Can I take this while breastfeeding?
What side effects should I watch for?
Does this work to prevent problems in newborns?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Colostrum Plus With Lactoferrin is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Colostrum Plus With Lactoferrin ’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Colostrum Plus With Lactoferrin 's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactoferrin 6 references
- Food and Drug Administration, CFSAN/Office of Food Additive Safety. Agency Response Letter GRAS Notice No. GRN 000130. 2003. Available at: http://www.cfsan.fda.gov/~rdb/opa-g130.html (Accessed 29 June 2005).
- Okada S, Tanaka K, Sato T, et al. Dose-response trial of lactoferrin in patients with chronic hepatitis C. Jpn J Cancer Res 2002;93:1063-9. PubMed
- Abu Hashim H, Foda O, Ghayaty E. Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials. Eur J Obstet Gynecol Reprod Biol. 2017;219:45-52. PubMed
- Tarnow-Mordi WO, Abdel-Latif ME, Martin A, et al. The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Health. 2020 Jun PubMed
- ELFIN trial investigators group. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Lancet. 2019 Feb 2;393(10170):423-433. doi: 10.1016/S0140-6736(18)32221-9.
- Lepanto MS, Rosa L, Cutone A, Conte MP, Paesano R, Valenti P. Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: An interventional study. Front Immunol. 2018 Sep 21;9:2123. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC