Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

Probiotic With Colostrum Ingredients & Drug Interactions

by Symbiotics

Probiotic With Colostrum label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Probiotic With Colostrum against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Probiotic With Colostrum is a dietary supplement by Symbiotics with 5 active ingredients. Its ingredients are commonly taken for immune support, gut health and digestion, exercise recovery.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Probiotic With Colostrum by Symbiotics

Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic With Colostrum by Symbiotics — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Probiotic With Colostrum by Symbiotics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 7 active ingredients.
  • “Bifidobacterium” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Lactobacilli:” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Bovine Colostrum” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

This product is a blend of 7 ingredients: live beneficial bacteria (probiotics) including Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus rhamnosus, Bifidobacterium breve, and Bifidobacterium lactis, plus Bifidobacterium as a group blend. It also contains bovine colostrum — the nutrient-rich first milk from cows — which supplies immunoglobulins and proline-rich polypeptides.

The inactive ingredients are hypromellose, medium-chain triglycerides, heat-treated rice flour, sunflower lecithin, silicon dioxide, and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive balance and health support.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Colic, Constipation, Inflammatory bowel disease (IBD), Irritable bowel syndrome (IBS) — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Inflammatory bowel disease (IBD), Lactose intolerance, Necrotizing enterocolitis (NEC), and more.

The evidence we hold shows Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis. It's rated possibly ineffective for atopic disease (eczema and allergies), and the evidence for acute respiratory distress syndrome (ARDS) isn't established.

For Bifidobacterium breve, the data we hold show it may not work for age-related cognitive decline or sepsis; evidence for allergic rhinitis (hay fever) and atopic disease isn't established yet, and we have no rating for antibiotic-associated diarrhea. We hold no effectiveness data for the other ingredients in this product.

The evidence, ingredient by ingredient Bovine Colostrum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Taking it with other probiotics — as you would in this product — may cause gastrointestinal side effects like epigastric discomfort, abdominal pain, bloating, flatulence, or diarrhea, though these are uncommon.

Rare but serious cases of infection (bacteremia, sepsis, endocarditis) have been reported, mostly in patients with other underlying conditions. Bifidobacterium breve is generally well tolerated in healthy people, but caution is advised if you're very ill or immunocompromised — rare cases of bacteremia have occurred, especially in critically ill infants and preterm infants.

Bloating and flatulence may occur with probiotic use. We have no safety data on file for Immunoglobulins, Proline-Rich Polypeptides, Lactobacillus rhamnosus, Lactobacillus plantarum, or Bifidobacterium lactis.

Side effects, ingredient by ingredient Bovine Colostrum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Breve.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, time this product carefully — separate your antibiotic dose from the probiotic by several hours, since antibiotics may reduce how well the live bacteria work. Several ingredients in this product could not be checked for drug interactions because we hold no data for them.

Use the search tool on this page to look up your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic blend may help if you have IBS, antibiotic-associated diarrhea, or certain infections — though evidence is modest. If you're taking antibiotics, separate them from this product so the antibiotics don't kill the live cultures.

If you're very ill, immunocompromised, or have a critical illness, talk with your doctor before starting it. Check with your own doctor or pharmacist about whether this product makes sense for your health and any medications you take.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Probiotic With Colostrum, straight from the product label.

Brand Symbiotics
Barcode (UPC) 647303070011
Net contents 60 Delayed Release Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2017
DSLD ID 75793
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Probiotic With Colostrum by Symbiotics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
647303070011
IngredientAmount% DV
Calories5 Calorie(s)--
Sugar1 Gram(s)--
Protein1 Gram(s)1%
Bifidobacterium0 NP--
Immunoglobulins198 mg--
Proline-Rich Polypeptides39.6 mg--
Lactobacilli:0 NP--
Bovine Colostrum1000 mg--
Ultra Defense Probiotic Blend200 mg--
Lactobacillus rhamnosus (Lr-04)0 NP--
Lactobacillus acidophilus (La-02)0 NP--
Lactobacillus plantarum (Lp-01)0 NP--
Bifidobacterium breve (Br-03)0 NP--
Bifidobacterium lactis (Bs-01)0 NP--

Other ingredients: Hypromellose, Medium Chain Triglycerides, heat treated Rice Flour, Sunflower Lecithin, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Combines probiotics with Colostrum for the synergistic support of digestive balance A cutting-edge, science based, combination of wholesome ingredients for digestive health support that represents the next generation in probiotic supplementation.

10 billion live microencapsulated cells derived from 5 clinically studied human probiotic strains

Every live cell has a protective coating which helps more live cells reach the intestine and grow better than uncoated probiotics.

What are probiotics? Probiotics are live microorganisms that are also known as “good” bacteria that help promote a healthy digestive tract and immune system. What is Colustrum? Colostrum is the first milk produced by mammals (cows) after birth and is particularly rich in immunoglobulins, immune supporting peptides (lactoferrin & lactoperoxidase) and other bioactive molecules, including growth factors. Combined, the bioactive natural compounds found in colostrum help promote immune health and support normal gastrointestinal tract health.

~ Helps promote digestive balance ~ Supports immune health

Ultra defense 10 billion live cells

The next generation in probiotic supplementation

Made in the U.S.A.

ITEM NO. 7001

Formula

2 Bifidobacterium strains for the large intestine. 3 Lactobacillus strains for the small intestine.

Synergy of probiotics and Colostrum

Contains: Milk (Instantized skim colostrum)

Brand IP Statement(s)

Superior stability and delivery with MicroGuard Microencapsulation Technology

Live probiotic cell MicroGuard Coating

Our MicroGuard coated probiotic strains also have the added protection of a delayed release capsule which resists harsh stomach acid better than standard capsules.

Symbiotics a trusted name in gut health & immune support

Expanding the Symbiotics brand to include a cutting edge probiotic line along with their market leading colostrum line is an important development for consumers looking to support their digestive health, particularly when considering the synergistic effect that probiotics and colostrum each provide for optimum gut health and immune support.

With MicroGuard Microencapsulation technology

2017 Prevention, LLC.

MicroBac is a registered trademark of Probiotical S.P.A. TempSURE is a registered trademark of Honeyville, Inc. MicroGuard is a trademark of Prevention, LLC.

Formulation

~ Gluten free

Free of GMOs, wheat, gluten, soy, eggs, shellfish, tree nuts, and artificial ingredients.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

C-7001-017 v26

Suggested/Recommended/Usage/Directions

Directions: Take two capsules daily. May be taken with or without food. Dosage may be increased to 6 capsules daily in times of environmental or physical stress.

Precautions

Contains: Milk (Instantized skim colostrum)

Storage

Formulated to provide at least 10 billion live cells per two capsules at time of consumption, if prior to expiration, under recommended storage conditions. Storage and handling conditions may vary, and may affect the total amount of live cells delivered at consumption.

For best results, store in the original blister package in a cool dry place at 73(0)F (23(0)C) or below. Best if refrigerated.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Probiotic With Colostrum by Symbiotics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Probiotic With Colostrum label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Probiotic With Colostrum by Symbiotics

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Protein

1 Gram(s) per serving

Bovine Colostrum

No known
interactions
1000 mg per serving

Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help w...

Bovine Colostrum monograph & interactions
  • › Immunoglobulins
  • › Proline-Rich Polypeptides

Ultra Defense Probiotic Blend

200 mg per serving
  • › Bifidobacterium
  • › Lactobacilli:

Other (inactive) ingredients: Hypromellose, Medium Chain Triglycerides, Heat treated Rice Flour, Sunflower Lecithin, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Probiotic With Colostrum by Symbiotics Drug Interactions

Want to check YOUR meds against Probiotic With Colostrum?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Probiotic With Colostrum interact with 182 drugs. Click any drug to see the details.

0 of the 5 ingredients in Probiotic With Colostrum interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Probiotic With Colostrum with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Probiotic With Colostrum, from the product label.

Symbiotics

See all Symbiotics products
Name
Naturade a division of Prevention, LLC
City
Irvine
State
CA
ZipCode
92614
Phone Number
1-800-421-1830
Web Address
www.symbiotics.com
Pharmacist Counseling Corner

Probiotic With Colostrum by Symbiotics: Common Questions

Does Probiotic With Colostrum by Symbiotics interact with any medications?
Yes. Based on its ingredients, Probiotic With Colostrum has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Probiotic With Colostrum contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with my antibiotic?
Not at the same time. Antibiotics can kill the live organisms in this probiotic, making it less effective. Separate your antibiotic dose from this product by a few hours — ask your doctor or pharmacist for the best timing for your specific antibiotic.
Is this safe during pregnancy?
Lactobacillus acidophilus is rated possibly safe in pregnancy, but data are limited. We have no safety information on file for the other ingredients. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy.
Could this cause stomach upset?
Gastrointestinal side effects like bloating, flatulence, abdominal pain, and diarrhea are uncommon but can happen when you combine probiotics. Most people tolerate it well.
Will this help my IBS?
Lactobacillus acidophilus is possibly effective for IBS, which means there's some evidence it may help, but the evidence isn't definitive. Results vary from person to person.
What's colostrum and why is it in here?
Colostrum is the first milk produced by cows after giving birth — it's nutrient-dense and contains immunoglobulins and proline-rich polypeptides that may support immunity. We hold no effectiveness data on these particular ingredients, though.
Is this safe if I'm immunocompromised or very ill?
Caution is advised. Rare but serious infections have been reported with Bifidobacterium breve in critically ill patients. Check with your doctor before starting this if you're very ill or have a weakened immune system.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Probiotic With Colostrum is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Probiotic With Colostrum label
Go deeper

The Full Monographs Behind Probiotic With Colostrum’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bovine Colostrum

Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help with gut health, certain types of diarrhe...

Read the full Bovine Colostrum monograph →
Sources

Sources & How We Checked

Probiotic With Colostrum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bovine Colostrum 8 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54. PubMed
  3. Duff WR, Chilibeck PD, Rooke JJ, Kaviani M, Krentz JR, Haines DM. The effect of bovine colostrum supplementation in older adults during resistance training. Int J Sport Nutr Exerc Metab. 2014 Jun;24(3):276-85. PubMed
  4. Sanctuary MR, Kain JN, Chen SY, et al. Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms. PLoS One. 2019;14(1):e0210064. PubMed
  5. Porcaro F, Caminiti L, Crisafulli G, Guglielmo F, Pajno GB. Anaphylaxis to cutaneous exposure to bovine colostrum based cream. Asian Pac J Allergy Immunol. 2019;37(1):9-11.
  6. Yan X, Pan X, Ding L, et al. Bovine colostrum to supplement the first feeding of very preterm infants: The PreColos randomized controlled trial. Clin Nutr 2023;42(8):1408-1417. PubMed
  7. Halasa M, Skonieczna-Zydecka K, Machalinski B, Bühner L, Baskiewicz-Halasa M. Six Weeks of Supplementation with Bovine Colostrum Effectively Reduces URTIs Symptoms Frequency and Gravity for Up to 20 Weeks in Pre-School Children. Nutrients 2023;15(16):3626 PubMed
  8. Simonsen MB, Kappel SS, Aunsholt L, Möller S, Sangild PT, Zachariassen G. Mineral supplementation for very preterm infants fed fortified human milk. J Pediatr Gastroenterol Nutr 2024;78(6):1389-1397. PubMed

See these in context on the Bovine Colostrum monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team