No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lecithin 411 mg Ingredients & Drug Interactions

by The Vitamin Shoppe

Softgel Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Lecithin 411 mg is a dietary supplement by The Vitamin Shoppe with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, liver health, brain and memory support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lecithin 411 mg by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Triple Strength Lecithin” is listed as a grouped ingredient — the label gives one combined amount (411 mg) without saying how much of each component you get.

This softgel contains five active ingredients centered around lecithin and its phospholipid components. Phosphatidylcholine is the main checked ingredient — a natural compound your body uses to build cell membranes and support liver function.

The product also contains linoleic acid and alpha-linolenic acid (essential fatty acids), phosphatidylethanolamine, and phosphatidylinositol, all part of the lecithin complex. Five inactive ingredients (gelatin, glycerin, polygycitol syrup, soybean oil, and water) make up the softgel capsule itself.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Choline and essential fatty acids support.
  • We looked for evidence on: Memory, Age-related cognitive decline, Dementia, Alzheimer disease, Hyperlipidemia, Hyperlipoproteinemia — and 4 related terms.
  • The strongest evidence on file: Phosphatidylcholine is rated "Possibly Effective" for Ulcerative colitis (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Hepatic encephalopathy, Hyperlipidemia, Hyperlipoproteinemia, and more.

The evidence we hold is limited. Phosphatidylcholine is rated possibly effective for ulcerative colitis, but the data for other common uses — including nonalcoholic fatty liver disease, alcohol-related liver damage, Alzheimer disease, and anxiety — falls short of what we'd call reliable.

If you're considering this product for a specific condition, talk it over with your doctor to see whether the evidence fits your situation.

The evidence, ingredient by ingredient Lecithin Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated when taken by mouth. The most common side effects are mild digestive ones: altered taste, bloating, diarrhea, nausea, and vomiting.

Very high doses (30 grams per day or more) are more likely to cause stomach upset and loose stools. Sweating and itching have also been reported.

During pregnancy, choline (which phosphatidylcholine provides) is an important nutrient, but we don't have solid safety data on supplements beyond food sources — talk with your doctor before taking this if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Lecithin Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That doesn't mean none exist — it means we have no monograph data flagging a concern.

If you take any prescription medications, confirm with your own doctor or pharmacist before starting.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Lecithin 411 mg is a straightforward lecithin supplement with no documented drug interactions for the ingredient we could assess. It's generally well tolerated but may cause mild digestive symptoms in some people, especially at higher doses.

If you're pregnant, breastfeeding, or taking prescription medications, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lecithin 411 mg, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536029679
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Jan 25, 2016
DSLD ID 55685
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lecithin 411 mg by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
766536029679
IngredientAmount% DV
Linoleic Acid140 mg--
Alpha-Linolenic Acid18 mg--
Phosphatidylcholine143 mg--
Phosphatidylethanolamine27 mg--
Phosphatidylinositol3 mg--
Triple Strength Lecithin411 mg--

Other ingredients: Gelatin, Glycerin, Polygycitol Syrup, Soybean Oil, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

easy to swallow

specialty

{softgel} actual size

Lecithin is a natural combination of phospholipids, choline, inositol, and the essential fatty acids (linoleic and linolenic).

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Formula

Choline Essential fatty acids

Contains: Soy.

FDA Statement of Identity

dietary supplement

Formulation

gluten free dairy free nut free

Does not contain: Yeast, Wheat, Gluten, Sugar, Salt, Dairy, Citrus, Fish, Preservatives, Artificial Colors or Flavors.

Precautions

Contains: Soy.

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper Evident DO not use if outer seal is broken or missing.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) softgel up to two (2) times daily, preferably with meals.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place.

General

Item No. VS-2967 1967249 DO 6

See for yourself

Lecithin 411 mg by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lecithin 411 mg by The Vitamin Shoppe

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Triple Strength Lecithin

No known
interactions
411 mg per serving Form: Phosphatidylcholine

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Triple Strength Lecithin monograph & interactions
  • › Linoleic Acid
  • › Alpha-Linolenic Acid
  • Phosphatidylcholine
  • › Phosphatidylethanolamine
  • › Phosphatidylinositol

Other (inactive) ingredients: Gelatin, Glycerin, Polygycitol Syrup, Soybean Oil, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lecithin 411 mg by The Vitamin Shoppe Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lecithin 411 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lecithin 411 mg, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Lecithin 411 mg by The Vitamin Shoppe: Common Questions

Does Lecithin 411 mg by The Vitamin Shoppe interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lecithin 411 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lecithin 411 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this upset my stomach?
It might cause mild digestive symptoms like bloating, nausea, diarrhea, or altered taste, especially if you take larger doses. Most people tolerate it well, but if your stomach is sensitive, starting with a low dose and taking it with food may help.
Can I take this while pregnant?
Choline — which phosphatidylcholine provides — is actually needed during pregnancy, but we don't have reliable safety data on supplements beyond what's in food. Talk with your doctor to see whether this supplement makes sense for you during pregnancy.
Is it safe to breastfeed while taking this?
We don't have enough reliable data on supplement use while breastfeeding. Check with your healthcare provider first to make sure it's right for you and your baby.
What is phosphatidylcholine and why is it in here?
It's a natural compound in lecithin that helps build and maintain cell membranes throughout your body. It's mainly studied for possible benefits in ulcerative colitis, though evidence for other conditions is still developing.
Does this help with liver health or fatty liver?
Phosphatidylcholine has been studied for nonalcoholic fatty liver disease and alcohol-related liver damage, but the evidence we have isn't strong enough to call it reliable for these uses. Talk with your doctor about whether it fits your needs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lecithin 411 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lecithin 411 mg label
Sources

Sources & How We Checked

Lecithin 411 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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