Lipanase Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Lipanase against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Lipanase is a dietary supplement by Douglas Laboratories with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Lipanase by Douglas Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Lipanase contains three active digestive enzymes. Protease breaks down proteins, lipase breaks down fats, and amylase breaks down carbohydrates — together they're meant to support the digestive process.
The tablet also includes microcrystalline cellulose, croscarmellose sodium, vegetable stearate, coating, and silica as inactive ingredients.
Does it work?
Couldn't assess
The evidence for these enzymes is limited. For both inflammatory bowel disease and indigestion (dyspepsia), the data we hold rates the evidence as insufficient to say whether lipase works.
There's also insufficient evidence for its use in premature infants. We don't hold effectiveness data for protease or amylase in this product.
How safe is it?
Well-documented data
Protease and lipase are generally well tolerated in adults, though either may cause digestive upset or allergic reactions in some people. Protease exposure in occupational settings has rarely triggered allergic reactions like allergic rhinitis or asthma, though this is not typical for supplement use.
For pregnancy, the safety data advises against protease unless your doctor prescribes it. Lipase has little safety data in pregnancy — use only if your doctor recommends it.
During breastfeeding, neither protease nor lipase is recommended without medical advice. We hold no pregnancy or breastfeeding data for amylase.
If you are pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this product.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Amylase could not be checked because we hold no monograph for it.
Before taking Lipanase with any prescription or over-the-counter medication, check with your doctor or pharmacist.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Lipanase is a three-enzyme digestive aid with limited evidence for the conditions listed on the label. It's generally well tolerated in adults, though it may cause digestive upset or, rarely, allergic reactions.
If you're pregnant, breastfeeding, or have a serious digestive condition, check with your doctor or pharmacist before starting. Run your medications through the interaction tool on this page to be sure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Lipanase, straight from the product label.
| Brand | Douglas Laboratories |
|---|---|
| Barcode (UPC) | 745287110119 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2022 |
| DSLD ID | 261221 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Lipanase by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Pancreatin | 300 mg | -- |
Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Vegetable Stearate, Coating, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take 1 tablet with each meal, or as directed by your health professional.
Precautions
Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.
Keep out of the reach of children.
Use only if safety seal is intact.
Storage
Store in a cool, dry place.
Formulation
Gluten-free, Non-GMO
Pancreatic enzyme support
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Lipanase by Douglas Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Lipanase by Douglas Laboratories
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Vegetable Stearate, Coating, Silica. These complete the product’s ingredient list but are not active constituents.
Lipanase by Douglas Laboratories Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Lipanase. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Lipanase, from the product label.
Douglas Laboratories
See all Douglas Laboratories products- Name
- Douglas Laboratories
- Street Address
- 600 Boyce Road
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15205
- Phone Number
- 1.800.245.4440
- Web Address
- www.douglaslabs.com
Lipanase by Douglas Laboratories: Common Questions
Does Lipanase by Douglas Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What do these enzymes do?
Can I take Lipanase if I'm pregnant?
Is this safe while breastfeeding?
What side effects might happen?
Does this actually work for indigestion or inflammatory bowel disease?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Lipanase is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Lipanase’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph →Sources & How We Checked
Lipanase's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC