No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Liposomal Hyaluronic Acid Ingredients & Drug Interactions

by Dr. Mercola

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Liposomal Hyaluronic Acid is a dietary supplement by Dr. Mercola with 1 active ingredient. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Liposomal Hyaluronic Acid by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: hyaluronic acid, a naturally occurring substance your body uses to retain moisture in skin, joints, and connective tissue. The capsule also holds several inactive ingredients—rice bran, gum acacia, hydroxypropyl methylcellulose, L-leucine, sunflower lecithin, and silicon dioxide—which are fillers and binders that help deliver the active ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Skin hydration and joint comfort support.
  • We looked for evidence on: Aging skin, Dry eye, Osteoarthritis, Wound healing, Gingivitis, Joint flexibility — and 3 related terms.
  • The strongest evidence on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Gingivitis, Osteoarthritis, Wound healing.

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing sores on the lower leg), based on the evidence we have. For aging skin, hay fever, and sexual dysfunction, the evidence isn't strong enough yet to rate it—we just don't have enough reliable data to say whether it works for those uses.

Talk with your pharmacist about whether this fits what you're trying to address.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth or applied to skin, hyaluronic acid is generally well tolerated in most adults. Topically, some people have reported eczema, redness, itching, and rarely wound infections.

Eye drops with hyaluronic acid have occasionally caused eye pain, though this is rare. The safety facts note that long-term safety of oral supplements isn't fully studied, and there isn't enough data to know whether oral supplements are safe for everyone—your doctor should sign off before you start.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for hyaluronic acid. That said, check your specific medications with the search tool on this page or ask your pharmacist, since the absence of documented interactions isn't a guarantee none exist.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Hyaluronic acid may help with dry eye or slow-healing leg sores. If you're thinking of taking this for aging skin or other uses, the evidence isn't there yet.

Talk to your doctor or pharmacist first, especially about long-term use—the safety data for oral supplements over time is still being worked out.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liposomal Hyaluronic Acid, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 810094213374
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 327178
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liposomal Hyaluronic Acid by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
810094213374
IngredientAmount% DV
Hyaluronic Acid100 mg--

Other ingredients: Rice Bran, Gum Acacia, Hydroxypropyl Methylcellulose, L-Leucine, Sunflower Lecithin, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults, as a dietary supplement, take one (1) capsule daily.

Precautions

Keep out of reach of children.

Do not use if safety seal broken.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

Formula

Liposomal Hyaluronic Acid 100 mg Per capsule

FDA Statement of Identity

Dietary Supplement

General Statements

Providing quality products since 2001.

Brand IP Statement(s)

LipoVantage is a registered of Spencnova, LLC.

See for yourself

Liposomal Hyaluronic Acid by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liposomal Hyaluronic Acid by Dr. Mercola

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Hyaluronic Acid

No known
interactions
100 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Other (inactive) ingredients: Rice Bran, Gum Acacia, Hydroxypropyl Methylcellulose, L-Leucine, Sunflower Lecithin, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liposomal Hyaluronic Acid by Dr. Mercola Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Liposomal Hyaluronic Acid. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Liposomal Hyaluronic Acid, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Liposomal Hyaluronic Acid by Dr. Mercola: Common Questions

Does Liposomal Hyaluronic Acid by Dr. Mercola interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Liposomal Hyaluronic Acid. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Liposomal Hyaluronic Acid contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is hyaluronic acid safe to take every day?
Taken by mouth or applied to skin, it's generally well tolerated. However, the long-term safety of oral supplements isn't fully studied. Your doctor should clear it before you use it regularly, especially over a long time.
Will this help my wrinkles or sagging skin?
The evidence for aging skin is insufficient—we don't have enough reliable data to say whether it works for that. It is possibly effective for dry eye and slow-healing leg ulcers, though.
What's in the capsule besides hyaluronic acid?
The capsule contains rice bran, gum acacia, hydroxypropyl methylcellulose, L-leucine, sunflower lecithin, and silicon dioxide. These are all inactive ingredients—fillers and binders that help deliver the hyaluronic acid.
Can I take this with my other medications?
No interactions are documented in our data for hyaluronic acid. Still, run your specific medications through the checker on this page or ask your pharmacist to be sure.
What side effects should I watch for?
Taken by mouth, hyaluronic acid is generally well tolerated. Topically, some people have reported redness, itching, or eczema. Eye pain has rarely been reported with eye drops. Stop and talk to your pharmacist if anything feels off.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liposomal Hyaluronic Acid is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liposomal Hyaluronic Acid label
Go deeper

The Full Monographs Behind Liposomal Hyaluronic Acid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Liposomal Hyaluronic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring