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Dietary supplement

Livatrate 475 mg Ingredients & Drug Interactions

by Progressive Professional from Progressive Laboratories

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Livatrate 475 mg is a dietary supplement by Progressive Professional from Progressive Laboratories with 1 active ingredient. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Livatrate 475 mg by Progressive Professional from Progressive Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Livatrate 475 mg contains one active ingredient: liver extract, a desiccated (dried) form of animal liver. The capsule also includes gelatin, rice flour, and vegetable lubricant as inactive ingredients to hold it together and make it easy to take.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for liver extract in chronic fatigue syndrome (CFS) is rated possibly ineffective — meaning it hasn't been shown to help. For hepatitis C, the data isn't reliable enough to say one way or the other.

The bottom line is that we don't have solid proof this product works for either condition.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been formally reported, but the safety profile hasn't been thoroughly studied. The bigger concern is source quality: liver extract comes from raw animal liver from slaughterhouses, and there's a risk of contamination from sick or diseased animals.

There's also a theoretical risk of bovine spongiform encephalitis (BSE, also called mad cow disease) in extracts from cows in countries where BSE has been reported — though no human cases from contaminated liver extract have been documented so far. Liver extract can deliver very high levels of vitamin A and iron, which matters if you're taking this long-term or at high doses.

The product is not recommended in pregnancy due to the high vitamin A content, which could harm a developing baby.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take warfarin (Coumadin) or any iron supplements or medications before adding this product. Altogether, these interactions span 3 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This product is a single-ingredient supplement with minimal studied effectiveness for the conditions it's marketed for. If you're taking warfarin or iron supplements, talk to your pharmacist before starting.

Given the source-quality concerns and high micronutrient levels, it's worth checking with your doctor first, especially if you're pregnant or have an iron-overload condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Livatrate 475 mg, straight from the product label.

Brand Progressive Professional from Progressive Laboratories
Barcode (UPC) 351821009827
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 261913
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Livatrate 475 mg by Progressive Professional from Progressive Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
351821009827
IngredientAmount% DV
Liver475 mg--

Other ingredients: Gelatin, Rice Flour, Vegetable Lubricant

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: One capsule three times daily, or more, as directed by a health care professional.

General Statements

Sold only for dispensing by a licensed health professional.

Precautions

Pregnant and/or lactating women should consult their physician prior to use.

Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.

Keep out of reach of children.

Formulation

Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)

Seals/Symbols

GMP Good Manufacturing Practice Certified GMP Compliant 21 CFR 111

Brand IP Statement(s)

Progressive Professional from Progressive Laboratories

Formula

Raw liver concentrate

FDA Statement of Identity

Dietary Supplement

See for yourself

Livatrate 475 mg by Progressive Professional from Progressive Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Livatrate 475 mg by Progressive Professional from Progressive Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Liver

Interacts with
3 drugs
475 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Liver monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Vegetable Lubricant. These complete the product’s ingredient list but are not active constituents.

Interaction report

Livatrate 475 mg by Progressive Professional from Progressive Laboratories Drug Interactions

Want to check YOUR meds against Livatrate 475 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Liver 3

Each ingredient & the kinds of drugs it affects

For each ingredient in Livatrate 475 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Livatrate 475 mg, from the product label.

Progressive Professional from Progressive Laboratories

See all Progressive Professional from Progressive Laboratories products
Name
Progressive Laboratories, Inc.
City
Irving
State
Texas
ZipCode
75038
Phone Number
1-800-527-9512
Pharmacist Counseling Corner

Livatrate 475 mg by Progressive Professional from Progressive Laboratories: Common Questions

Does Livatrate 475 mg by Progressive Professional from Progressive Laboratories interact with any medications?
Yes. Based on its ingredients, Livatrate 475 mg has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Livatrate 475 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does liver extract help with chronic fatigue?
The evidence says it's possibly ineffective — meaning research hasn't shown it works for chronic fatigue syndrome. It's not a reliable choice if that's what you're looking for.
What's in this product besides the liver extract?
The capsule itself contains gelatin, rice flour, and vegetable lubricant. These are inactive fillers that help hold the capsule together — they're not active ingredients.
Can I take this if I'm pregnant?
No. Liver extract contains very high amounts of vitamin A, which can harm a developing baby. Avoid it unless your doctor specifically advises you otherwise.
Are there any reported side effects?
No adverse reactions have been formally reported, but safety hasn't been thoroughly studied. There is concern about contamination from the source animal liver and, theoretically, BSE in products from countries where it's been reported — though no human cases from contaminated liver extract have occurred.
Can I take this with iron supplements?
Be cautious. Liver extract contains heme iron, so adding it to iron supplements could increase your total iron intake and raise the risk of stomach upset or iron buildup. Check with your pharmacist first, especially if you take high doses or use it long-term.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Livatrate 475 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Livatrate 475 mg label
Sources

Sources & How We Checked

Livatrate 475 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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