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Dietary supplement

Lobelia Ingredients & Drug Interactions

by Herbs Etc.

Lobelia label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lobelia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lobelia is a dietary supplement by Herbs Etc. with 1 active ingredient. Its ingredients are commonly taken for asthma and breathing problems, cough and bronchitis, smoking cessation aid.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are fresh Lobelia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lobelia by Herbs Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Lobelia by Herbs Etc. — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lobelia by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: fresh lobelia in a liquid form. The preparation also includes grain alcohol (40%) and purified water as inactive ingredients to deliver the herb.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lobelia product and its label doesn't state a use — see Lobelia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

Lobelia is rated possibly ineffective for smoking cessation based on the evidence we hold. If you're considering this product for that purpose, the data doesn't support that it will work.

The evidence, ingredient by ingredient Lobelia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lobelia carries serious safety warnings. It can be toxic, especially at higher doses, and the adverse effects are real and sometimes severe.

Even at doses as low as 50 mg, people have reported nausea, vomiting, diarrhea, coughing, dizziness, tremors, and throat irritation. At 600 mg or higher, toxicity symptoms include sweating, rapid heart rate, convulsions, low body temperature, low blood pressure, and in severe cases, coma or death.

The product should not be used during pregnancy or while breastfeeding — the safety data rates it likely unsafe due to toxicity concerns and lack of adequate safety information. If you're pregnant, planning to become pregnant, or nursing, avoid this product entirely.

Side effects, ingredient by ingredient Lobelia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lobelia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, do not start this product without talking to your pharmacist or doctor first — lobelia may raise your lithium levels and your dose may need adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lobelia is a potent herb with real toxicity risks, especially at higher doses. It's not recommended for pregnancy or breastfeeding.

If you take lithium, you must check with your pharmacist before using it. For anyone else considering it, the evidence for smoking cessation doesn't support its use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lobelia, straight from the product label.

Brand Herbs Etc.
Net contents 8 fl. Oz.; 236 mL
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50353
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lobelia by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
IngredientAmount% DV
fresh Lobelia0 NP--

Other ingredients: 40% Grain Alcohol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Herbal Single

Professional Strength

Fresh herb extract

For dispensing purposes only

Formula

Lobelia inflata

FDA Statement of Identity

Fast-Acting Dietary Supplement

General

99126

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lobelia by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lobelia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lobelia by Herbs Etc.

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0 Not Present Dosage formLiquid Amounts shown are per serving.

Fresh Lobelia

Interacts with
1 drug
0 NP per serving

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking...

Fresh Lobelia monograph & interactions

Other (inactive) ingredients: 40% Grain Alcohol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lobelia by Herbs Etc. Drug Interactions

Want to check YOUR meds against Lobelia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

fresh Lobelia 1

Individual Drug Interactions

The ingredients in Lobelia interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Lobelia interact with drugs. Each result below shows which ingredient is responsible. fresh Lobelia

Each ingredient & the kinds of drugs it affects

For each ingredient in Lobelia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

fresh Lobelia1 drug type · 1 drug

Lithium

Lobelia is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, lobelia might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
fresh Lobelia full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lobelia, from the product label.

Herbs Etc.

Name
Herbs, Etc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Lobelia by Herbs Etc.: Common Questions

Does Lobelia by Herbs Etc. interact with any medications?
Yes. Based on its ingredients, Lobelia has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lobelia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this while pregnant or breastfeeding?
No. Lobelia is rated likely unsafe in pregnancy and while breastfeeding due to toxicity concerns and lack of safety data. If you're pregnant, planning pregnancy, or nursing, skip this product and talk with your doctor about alternatives.
What side effects might I experience?
Even at lower doses, lobelia can cause nausea, vomiting, diarrhea, coughing, dizziness, tremors, and throat irritation. At higher doses (600 mg or more), toxicity becomes a serious risk, with symptoms like rapid heart rate, low blood pressure, convulsions, and in severe cases, coma or death.
Does this product actually help with quitting smoking?
No. Lobelia is rated possibly ineffective for smoking cessation, so the evidence doesn't support it will help you quit.
Why is caution so strongly advised with lobelia?
Because lobelia is toxic at higher doses. Serious effects — including rapid heart rate, low blood pressure, convulsions, and even death — have been documented. That's why dosing and supervision matter a lot, and why it's not recommended for home use without medical guidance.
What's in this liquid besides the herb?
The product contains 40% grain alcohol and purified water as the carrier. If you need to avoid alcohol, this form may not be right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lobelia is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lobelia label
Go deeper

The Full Monographs Behind Lobelia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lobelia

Interacts with 1 drug

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking. It can be toxic in higher amounts, cau...

Read the full Lobelia monograph →
Sources

Sources & How We Checked

Lobelia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lobelia 6 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. McChargue DE, Collins FL Jr, Cohen LM. Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during 48-h smokeless tobacco deprivation. Nicotine Tob Res 2002;4:195-200. PubMed
  5. Stead LF, Hughes JR. Lobeline for smoking cessation. Cochrane Database Syst Rev 2000;2:CD000124. PubMed
  6. Plakun, A. L., Ambrus, J., Bross, I., Graham, S., Levin, M. L., and Ross, C. A. Clinical factors in smoking withdrawal: preliminary report. Am J Public Health Nations.Health 1966;56(3):434-441. PubMed

See these in context on the Lobelia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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