No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lutein 20 mg Ingredients & Drug Interactions

by GNC Natural Brand

Softgel Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lutein 20 mg is a dietary supplement by GNC Natural Brand with 1 active ingredient. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lutein 20 mg by GNC Natural Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lutein, a natural pigment found in leafy greens and other plants. Lutein accumulates in the eye and is thought to filter blue light and protect the retina from damage.

The softgel also contains several inactive ingredients — soybean oil, gelatin, safflower oil, glycerin, beeswax, and soy lecithin — that help deliver the lutein.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports eye health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Diabetic retinopathy, Dry eye — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Lutein is rated "Possibly Ineffective" for Retinitis pigmentosa.

The evidence suggests lutein may help with age-related macular degeneration (AMD) and cataracts — both rated possibly effective. For retinitis pigmentosa (a progressive inherited eye disease), retinopathy of prematurity (an eye condition in premature infants), necrotizing enterocolitis (a serious digestive disorder), and bronchopulmonary dysplasia (a lung condition), the data shows possibly ineffective.

That means either the research hasn't borne out a benefit or the studies are too thin to draw a firm conclusion.

The evidence, ingredient by ingredient Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein at 20 mg daily is generally well tolerated, and dietary sources are considered safe. The facts note that lutein is naturally present in breast milk.

For pregnancy and lactation, the data rates lutein as likely safe — though the notes also advise caution because there isn't enough research on higher supplement doses in pregnancy or nursing. Talk it over with your doctor or midwife if you're expecting or breastfeeding.

Side effects, ingredient by ingredient Lutein

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for lutein in our data. You may still want to mention this supplement to your pharmacist when you pick up or refill any medications, just to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward lutein supplement at a common dose, with no drug interactions documented. It may help with AMD or cataracts, though the evidence is modest.

If you're pregnant, nursing, or have any eye condition you're treating, check with your doctor or pharmacist before starting — they know your full health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein 20 mg, straight from the product label.

Brand GNC Natural Brand
Barcode (UPC) 048107166410
Net contents 120 Softgel(s)
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 82103
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein 20 mg by GNC Natural Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
048107166410
IngredientAmount% DV
Lutein20 mg--

Other ingredients: Soybean Oil, Gelatin, Safflower Oil, Glycerin, Beeswax, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

General Statements

Supports eye health

Actual size

General

CODE 722221 ARG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one softgel capsule daily.

Formulation

No sugar, no starch, no artificial colors, no artificial flavors, no preservatives, sodium free, no wheat, gluten free, no corn, no dairy yeast free.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Lutein 20 mg by GNC Natural Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lutein 20 mg by GNC Natural Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Lutein

No known
interactions
20 mg per serving Form: Marigold extract

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Safflower Oil, Glycerin, Beeswax, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein 20 mg by GNC Natural Brand Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lutein 20 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lutein 20 mg, from the product label.

GNC Natural Brand

See all GNC Natural Brand products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
www.gnc.com
Pharmacist Counseling Corner

Lutein 20 mg by GNC Natural Brand: Common Questions

Does Lutein 20 mg by GNC Natural Brand interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lutein 20 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lutein 20 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lutein actually work for macular degeneration?
The evidence says possibly effective — lutein may help, but we don't have the strongest proof yet. The research is promising enough that many eye doctors suggest it, but it's not a cure. Talk with your ophthalmologist about whether it's right for you.
Is it safe to take this while I'm breastfeeding?
The data rates lutein as likely safe in pregnancy and lactation, but the caution note says there isn't enough research on higher supplement doses while nursing. Your own doctor or lactation consultant can weigh whether this dose is right for you.
What's soy lecithin in here, and is it a problem if I'm avoiding soy?
Soy lecithin is an inactive ingredient — a binder and emulsifier in the softgel. If you have a soy allergy or are avoiding soy for other reasons, you should pick a different brand.
Can I take 20 mg of lutein every day without side effects?
Yes — the data shows that doses up to 20 mg daily are generally well tolerated with no reported adverse effects.
Does this product interact with my blood pressure or heart medications?
No interactions are documented in our data for lutein. That said, it's always smart to mention any new supplement to your pharmacist when you're on prescription drugs, so they can double-check your full profile.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein 20 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein 20 mg label
Go deeper

The Full Monographs Behind Lutein 20 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lutein 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring