No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lutein 20 mg Ingredients & Drug Interactions

by GNC Natural Brand

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lutein 20 mg is a dietary supplement by GNC Natural Brand with 1 active ingredient. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lutein 20 mg by GNC Natural Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lutein at 20 mg per capsule. Lutein is a yellow-orange pigment found naturally in leafy greens and other plants; your body deposits it in the eye, particularly the macula (the central part of the retina responsible for sharp vision).

The remaining ingredients are inactive — spinach powder, microcrystalline cellulose (a binder), gelatin capsule, and several other fillers and flow agents that help the capsule hold together and flow through manufacturing.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Supports eye health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Lutein is rated "Insufficient Reliable Evidence To Rate" for Diabetic retinopathy, Dry eye, Glaucoma, Myopia, and more.

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts — the two eye conditions where the evidence is strongest, though still not conclusive. For retinitis pigmentosa, retinopathy of prematurity, bronchopulmonary dysplasia, and necrotizing enterocolitis, the data suggests it is likely ineffective.

If you're considering this supplement for AMD or cataract prevention or management, talk with your eye doctor about whether it fits into your plan.

The evidence, ingredient by ingredient Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein from food and typical supplement doses is generally well tolerated. Doses up to 20 mg daily — the amount in this product — have not produced adverse effects in the studies we've reviewed.

Lutein is naturally present in breast milk, and the safety data advises caution with higher supplement doses during pregnancy and lactation because long-term studies haven't been done; there isn't enough data to know either way, so talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Lutein

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the lutein in this product. That said, run your exact medications through the search tool on this page to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a single-ingredient lutein supplement that may be worth considering if you're concerned about AMD or cataracts and want to add lutein from a supplement rather than food alone. If you're pregnant, nursing, or taking any prescription medications, check with your pharmacist first — not because of known interactions with lutein, but to make sure it fits your full health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein 20 mg, straight from the product label.

Brand GNC Natural Brand
Barcode (UPC) 048107107321
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 314035
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein 20 mg by GNC Natural Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
048107107321
IngredientAmount% DV
Lutein20 mg--

Other ingredients: Spinach, Powder, Microcrystalline Cellulose, Gelatine, Alginate, Gum Arabic, Pea Starch, Magnesium Stearate, Rosemary extract, Silicon Dioxide, Sodium Lauryl Sulfate, Sunflower Lecithin, Zeaxanthin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

For More Information: 1-888-462-2548 GNC.com

Actual size 60-Day Supply

Precautions

Keep out of reach of children.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition.

Discontinue use two weeks prior to surgery.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Supports eye health

No artificial flavors, gluten free. GF Gluten free

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one capsule daily.

See for yourself

Lutein 20 mg by GNC Natural Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lutein 20 mg by GNC Natural Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Lutein

No known
interactions
20 mg per serving Form: Marigold Flower Extract

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Other (inactive) ingredients: Spinach, Powder, Microcrystalline Cellulose, Gelatine, Alginate, Gum Arabic, Pea Starch, Magnesium Stearate, Rosemary extract, Silicon Dioxide, Sodium Lauryl Sulfate, Sunflower Lecithin, Zeaxanthin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein 20 mg by GNC Natural Brand Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lutein 20 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lutein 20 mg, from the product label.

GNC Natural Brand

See all GNC Natural Brand products
Name
GNC Holdings, LLC
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
GNC.com
Pharmacist Counseling Corner

Lutein 20 mg by GNC Natural Brand: Common Questions

Does Lutein 20 mg by GNC Natural Brand interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lutein 20 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lutein 20 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lutein actually work for macular degeneration or cataracts?
The evidence says possibly effective for both — meaning there's some support, but it's not proven yet. If you have or are at risk for either condition, ask your eye doctor whether adding lutein makes sense for you alongside any other treatment.
Is 20 mg a day safe?
Yes. Lutein doses up to 20 mg daily haven't shown adverse effects in studies, and it's generally well tolerated by mouth. If you have questions about your personal health, check with your pharmacist.
Can I take this if I'm pregnant or breastfeeding?
The data rates lutein as likely safe in pregnancy and lactation, but supplement doses haven't been well studied long-term, so there isn't enough information to know either way. Talk with your doctor or pharmacist for personalized advice.
What's spinach powder doing in here?
Spinach is a natural source of lutein — the supplement's active ingredient. It's part of the formula, not just a filler.
Will this interact with my blood pressure or heart medications?
No interactions are documented for lutein with those drug types. Still, use the search tool on this page to check your exact medications — it's the safest way to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein 20 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein 20 mg label
Go deeper

The Full Monographs Behind Lutein 20 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Lutein 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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