No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Maca 500 mg Ingredients & Drug Interactions

by Best Naturals

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Maca 500 mg is a dietary supplement by Best Naturals with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maca 500 mg by Best Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: maca root at 500 mg per capsule. Maca is a plant native to Peru, traditionally used for various purposes including fertility and sexual function, though the evidence base for most uses remains limited.

The capsule also contains inactive ingredients — gelatin, silica, and stearate — which are fillers and binders that hold the supplement together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Maca's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support male and female reproductive health.
  • We looked for evidence on: Age-related testosterone deficiency, Antidepressant-induced sexual dysfunction, Male infertility, Sexual desire, Postmenopausal conditions, Female sexual dysfunction — and 1 related terms.
  • The closest evidence on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction (Natural Medicines).
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Postmenopausal conditions, Sexual desire, Age-related testosterone deficiency, Male infertility.

The evidence for maca's effectiveness is insufficient to rate across the conditions tested in our data: amenorrhea (absent periods), anemia of chronic disease, antidepressant-induced sexual dysfunction, athletic performance, and osteoporosis. That means the studies we have aren't strong enough yet to say whether it works for any of these uses.

If you're considering maca for a specific health goal, talk it over with your doctor or pharmacist about what the current science supports.

The evidence, ingredient by ingredient Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maca is generally well tolerated when used as a food, but long-term safety as a supplement hasn't been well studied. One thing to note: eating fresh, uncooked maca may cause stomach pain, though this product is a processed supplement form.

During pregnancy, there isn't enough safety data in supplement amounts to recommend it — the facts advise against use. Similarly, there's not enough reliable information on safety while breastfeeding, so talk with your doctor or pharmacist if you're pregnant or nursing and thinking about adding this.

Side effects, ingredient by ingredient Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That doesn't mean none exist elsewhere, so if you take any medications regularly, run them through the search tool on this page or ask your pharmacist before adding maca.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Maca is generally well tolerated, and no medication interactions are documented for it. However, the evidence that it actually works for the conditions people typically take it for remains limited.

If you're pregnant or breastfeeding, the safety data advises against it. Before starting, mention it to your own doctor or pharmacist — they can help you weigh whether it's right for you and your health goals.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maca 500 mg, straight from the product label.

Brand Best Naturals
Barcode (UPC) 817716011271
Net contents 250 Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 269833
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maca 500 mg by Best Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
250
UPC/BARCODE
817716011271
IngredientAmount% DV
Maca500 mg--

Other ingredients: Gelatin, Silica, Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Maca has been imported traditional food and medicinal plant for over 2000 years. Maca is naturally rich in essential minerals, especially selenium, calcium, magnesium and iron, and fatty acid including; linolenic acid, palmitic acid, oleic acid and 19 amino acids, as well as polysaccharides. Maca's reported benefits for sexual vigor and health could be due to its high concentration of protein and vital nutrients and the root's unique nutritional profile, which provides optimum levels of nutrients utilized by the body's endocrine system without adversely impacting hormone levels

Rich source of minerals, fatty acids and amino acids

Formulation

Support male and female reproductive health. Supports healthy stamina, energy and sexual function

Reproductive health

Energizing herb Supports healthy stamina, energy & vigor

No artificial flavor or sweetener, no preservatives, no sugar, no starch no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish. Sodium free.

Precautions

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Keep in cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to cure, prevent, treat or diagnose any disease.

Seals/Symbols

Made in USA

GMP Good Manufacturing Practice Product

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) capsule one to three times daily, or as directed by your qualified healthcare professional.

See for yourself

Maca 500 mg by Best Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maca 500 mg by Best Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container250 Amounts shown are per serving.

Maca

No known
interactions
500 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca monograph & interactions

Other (inactive) ingredients: Gelatin, Silica, Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maca 500 mg by Best Naturals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maca 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maca 500 mg, from the product label.

Best Naturals

See all Best Naturals products
Name
Best Naturals
Street Address
PO Box 394
City
Kenilworth
State
NJ
ZipCode
07033
Phone Number
1-877-659-6004
Web Address
www.shopbestnaturals.com
Pharmacist Counseling Corner

Maca 500 mg by Best Naturals: Common Questions

Does Maca 500 mg by Best Naturals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maca 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maca 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against maca during pregnancy because there isn't enough information in supplement amounts. If you're breastfeeding, there's also not enough reliable information to know either way. Talk with your doctor or pharmacist for personalized advice on whether it's right for you.
Does maca actually improve sexual function?
The evidence for maca on antidepressant-induced sexual dysfunction is insufficient to rate — meaning the studies so far aren't strong enough to say it works. If sexual function is your main goal, ask your doctor what the current science supports.
Will this help with my irregular periods?
The evidence for maca on amenorrhea (absent or irregular periods) is insufficient to rate, so we don't have strong data showing it works for that. Your doctor can discuss what treatments have better evidence behind them.
What's in the capsule besides maca?
The capsule itself is gelatin, and the formula also contains silica and stearate — all inactive ingredients that help hold the supplement together and deliver it. There's one active ingredient: maca at 500 mg.
Will this upset my stomach?
Fresh, uncooked maca may cause stomach pain, but this is a processed supplement form. Overall, maca is generally well tolerated, though long-term safety as a supplement hasn't been thoroughly studied.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maca 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maca 500 mg label
Go deeper

The Full Monographs Behind Maca 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Maca 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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