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Dietary supplement

Moringa 500 mg Ingredients & Drug Interactions

by Best Naturals

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Moringa 500 mg is a dietary supplement by Best Naturals with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement, blood sugar support, cholesterol support.Based on those ingredients, 869 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Moringa, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Moringa 500 mg by Best Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This is a single-ingredient product: moringa powder in a 500 mg capsule. Moringa is a plant leaf sometimes called a "superfood," though its effectiveness for health conditions isn't well established in the data we hold.

The capsule itself contains inactive ingredients — magnesium stearate (a flow agent) and silicon dioxide (an anti-caking agent) — that help it hold together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Moringa product and its label doesn't state a use — see Moringa's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we have for moringa is insufficient to rate it reliably for any of the conditions it's traditionally used for — iron deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, and high cholesterol. This doesn't mean it doesn't work; it means good-quality human studies are lacking.

If you're considering it for a specific health goal, talk it over with your doctor so you can weigh what's known against your own situation.

The evidence, ingredient by ingredient Moringa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Moringa leaf powder is generally well tolerated, and a trial of 8 grams daily showed it caused only transient diarrhea in a small number of participants. However, high-quality safety data are limited.

Rare allergic reactions, including severe ones, have been reported. One case of Stevens-Johnson syndrome (a serious skin and mouth reaction) was linked to eating food containing moringa leaves, though this is uncommon.

Avoid medicinal amounts if you're pregnant, because moringa root and bark may stimulate the uterus, and safety data are lacking. If you're breastfeeding and thinking of taking medicinal amounts, safety hasn't been well studied — ask your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Moringa

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Moringa.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 870 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you're on levothyroxine (Synthroid or generic) for thyroid replacement, drugs processed by the liver enzyme CYP3A4 (a very large group that includes many statins, blood pressure pills, and immunosuppressants), or P-glycoprotein substrate drugs like certain cancer medications. Also mention it if you take diabetes medications or drugs processed by CYP1A2 (including some antidepressants and pain relievers).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Moringa is a leaf powder with limited safety concerns if used as food, but before you take this supplement, you need to clear it with your own doctor or pharmacist — especially if you take thyroid medication, HIV drugs, or anything processed by your liver. The evidence for what it actually does is still being built.

A pharmacist can check your specific medications against the interaction data on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Moringa 500 mg, straight from the product label.

Brand Best Naturals
Barcode (UPC) 817716010007
Net contents 180 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 270678
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Moringa 500 mg by Best Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
817716010007
IngredientAmount% DV
Moringa, Powder500 mg--

Other ingredients: Capsule, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Best Naturals uses the finest Moringa Oleifera leaves and pods. This nutrient dense food is rich in vitamins A, B, C and the minerals iron & potassium. It is a complete protein source containing essential amino acids as well as coenzymes and antioxidants. Moringa can be a healthy addition to any diet and may contribute to overall health. Certain research publications indicate that Moringa may help support the following: Supports healthy blood sugar level. Supports healthy kidney and liver function. Supports healthy weight management.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) capsule one to two times daily, preferably with meals or as directed by your qualified health care professional.

Precautions

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Discontinue use and consult your doctor if any adverse reaction occur.

Storage

Keep in cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Made in USA

GMP Good Manufacturing Practice Product

Formulation

Premium formula

3rd party lab tested

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no corn, no soy, no egg, no lactose, no gluten, no wheat, no yeast, no fish. Sodium free.

FDA Statement of Identity

Dietary Supplement

General Statements

For additional information call 1-877-659-6004

See for yourself

Moringa 500 mg by Best Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Moringa 500 mg by Best Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Moringa, Powder

Interacts with
869 drugs
500 mg per serving

Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....

Moringa, Powder monograph & interactions

Other (inactive) ingredients: Capsule, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Moringa 500 mg by Best Naturals Drug Interactions

Want to check YOUR meds against Moringa 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
869Drugs
717 Moderate 152 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Moringa 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Moringa, Powder6 drug types · 869 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Possible Evidence D
Levothyroxine (Synthroid, Others)

Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Nevirapine (Viramune)

Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Moringa 500 mg, from the product label.

Best Naturals

See all Best Naturals products
Name
Best Naturals
Street Address
PO Box 394
City
Kenilworth
State
NJ
ZipCode
07033
Phone Number
1-877-659-6004
Web Address
www.shopbestnaturals.com
Pharmacist Counseling Corner

Moringa 500 mg by Best Naturals: Common Questions

Does Moringa 500 mg by Best Naturals interact with any medications?
Yes. Based on its ingredients, Moringa 500 mg has a known interaction with 869 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Moringa 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
The data on moringa in pregnancy is mixed — it's rated both possibly safe and possibly unsafe, depending on the part of the plant and how much you take. The safety concern is mainly with the root and bark, which may stimulate the uterus. Since the evidence isn't clear, talk with your doctor or pharmacist before taking it; they can help you decide based on your individual situation.
What are the side effects?
Most people tolerate it well. The most common side effect is transient diarrhea — in one trial, about a quarter of people who took 8 grams daily had it, and it was temporary. Rare allergic reactions, including anaphylaxis, and one reported case of a serious skin and mouth reaction have been linked to moringa.
Does moringa actually work for diabetes?
We don't have reliable evidence yet. Animal research shows moringa can lower blood sugar, but human studies haven't been consistent. If you have diabetes, don't rely on this supplement instead of your prescribed medications — talk with your doctor first.
Is this safe to use while breastfeeding?
Moringa leaf is rated possibly safe for breastfeeding, and it's been traditionally used to boost milk supply. However, safety hasn't been well studied, so if you want to take medicinal amounts, ask your doctor or pharmacist for personalized advice.
What exactly is moringa?
Moringa is a plant leaf, sometimes called a superfood. This product is the powder form in a capsule. It contains no fillers other than the inactive ingredients listed — magnesium stearate and silicon dioxide, which are standard capsule materials.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Moringa 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Moringa 500 mg label
Sources

Sources & How We Checked

Moringa 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Moringa 23 references
  1. Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
  2. Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000;41:319-23. PubMed
  3. Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
  4. Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
  5. Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
  6. Monera TG, Wolfe AR, Maponga CC, et al. Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2008;2:379-83.
  7. Estrella M, Mantaring J, David G, Taup M. A double blind, randomised controlled trial on the use of malunggay (Moringa oleifera) for augmentation of the volume of breastmilk among non-nursing mothers of preterm infants. Philipp J Pediatr 2000;49:3-6.
  8. Morton, J. F. The Horseradish Tree, Moringa Pterygosperma (Moringaceae) - a boon to arid lands? Economic Botany 1991;45:318-333. DOI
  9. Espinosa-Kuo CL. A Randomized Controlled Trial on the Use of Malunggay (Moringa oleifera) for Augmentation of the Volume of Breastmilk Among Mothers of Term Infants. Filipino Family Physician. 2005;43(1):26-33.
  10. King JS, Raguindin PFN, Dans LF. Moringa oleifera (Malunggay) as a Galactagogue for Breastfeeding Mothers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Philipp J Pediatr 2013;61(2):34-42.
  11. Singh D, Choudhury S, Singh TU, Garg SK. Pharmacodynamics of uterotonic effect of Moringa oleifera flowers extract. J Vet Pharmcol Toxicol 2008;7(1-2):12-15.
  12. William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
  13. Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017;14:12. doi: 10.1186/s1 PubMed
  14. Witharana EWRA, Wijetunga WMGASTB, Wijesinghe SKJ. Stevens - Johnson syndrome (SJS) following murunga leaf (Moringa oleifera) consumption. Ceylon Med J 2018;63(4):188-9.
  15. Nur R, Demak IPK, Radhiah S, Rusydi M, Mantao E, Larasati RD. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women. Enferm Clin. 2020;30 Suppl 4:79-82. DOI
  16. Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M
  17. Sumiaty, Tahir A, Burhanuddin B, Nurhaedar J, Veni H. The effect of moringa leaves on pregnancy on growth and morbidity of 6-11 month. Enferm Clin. 2020;30 Suppl 4:104-108. DOI
  18. Ulmy MN, Tahir A, Arsunan AA, Burhanuddin B, Veni H. Effect of moringa leaves during pregnancy on growth and morbidity in 0-5 months. Enferm Clin. 2020;30 Suppl 4:61-65. DOI
  19. Amaeze O, Marques ES, Wei W, et al. Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction. Curr Drug Metab. 2021;22(14):1103-1113. PubMed
  20. Ebhohon E, Miller D. Moringa Oleifera leaf extract induced pulmonary embolism-a case report. Int J Emerg Med 2022;15(1):16. PubMed
  21. Basri H, Hadju V, Zulkifli A, Syam A, Indriasari R. Effect of Moringa oleifera supplementation during pregnancy on the prevention of stunted growth in children between the ages of 36 to 42 months. J Public Health Res 2021;10(2):2207.
  22. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  23. Amsler E, Mahevas T, Soria A, Barbaud A. Fixed food eruption to Moringa oleifera. Contact Dermatitis 2023;89(4):301-302.

See these in context on the Moringa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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