No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Maca Plus Pygeum Ingredients & Drug Interactions

by DC

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Maca Plus Pygeum is a dietary supplement by DC with 2 active ingredients. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maca Plus Pygeum by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has two active ingredients. Maca extract is a plant used traditionally for various health purposes, though evidence for many of them is limited.

Pygeum extract comes from the bark of an African tree and is best studied for benign prostatic hyperplasia—enlarged prostate in men. The capsule itself is made from vegetable cellulose and gelatin, with vegetable magnesium stearate and silica as inactive ingredients to help keep everything stable.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: prostate health and male sexual function.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Sexual desire, Male infertility, Age-related testosterone deficiency, urinary symptoms, libido.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pygeum is rated "Insufficient Reliable Evidence To Rate" for Sexual desire.
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Sexual desire, Age-related testosterone deficiency, Male infertility.

Pygeum has been found likely effective for benign prostatic hyperplasia (BPH)—the enlarged prostate condition common in older men. Maca extract has been tested for a range of uses—from amenorrhea (missing periods) to athletic performance to osteoporosis—but the evidence for all of them is insufficient right now.

The same goes for pygeum in uses beyond BPH, like sexual desire or Alzheimer disease. If either ingredient interests you for a specific reason, that's worth discussing with your doctor, since the research may not back up how you're thinking of using it.

The evidence, ingredient by ingredient Maca Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated in the short term, but maca has not been studied long term as a supplement, and pygeum's quality and long-term safety data are limited. Uncooked maca can cause stomach pain in some people.

Pygeum has been linked to nausea and belly pain in clinical trials, though rates were similar to placebo. Maca should be avoided during pregnancy—there isn't enough safety data.

The same goes for breastfeeding. Pygeum is designed for men's prostate health and has no established safe use in pregnancy; it's also best avoided while breastfeeding due to lack of safety information.

Side effects, ingredient by ingredient Maca Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients in this product. That said, run your medications through the search tool on this page before you begin, and if you take any blood thinners, heart medications, diabetes drugs, or anything that affects hormone levels, mention this supplement to your pharmacist or doctor first.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're a man considering pygeum for prostate health, this supplement has decent evidence behind it. Maca is less proven for most uses.

Neither ingredient has documented drug interactions, but that's not a guarantee none exist—check your specific medications with your doctor or pharmacist before you start. Pregnant women and those breastfeeding should steer clear of both ingredients.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maca Plus Pygeum, straight from the product label.

Brand DC
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 266173
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Women (not pregnant or lactating), Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maca Plus Pygeum by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Maca Extract300 mg--
Pygeum Extract40 mg--

Other ingredients: Vegetable Cellulose, Gelatin, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 capsule twice daily.

Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

Formulation

FDA Registered Facility (Reg. #1023013) Mfg. under Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Gluten free

Nutritionally supports healthy prostate function

Made in USA

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Quali Pure

FDA Statement of Identity

Dietary Supplement

See for yourself

Maca Plus Pygeum by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maca Plus Pygeum by DC

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Maca Extract

No known
interactions
300 mg per serving Form: Macaenes, Macamides

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca Extract monograph & interactions

Pygeum Extract

No known
interactions
40 mg per serving Form: Triterpenes

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum Extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Gelatin, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maca Plus Pygeum by DC Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maca Plus Pygeum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maca Plus Pygeum, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
Street Address
304 Dee Cee Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Maca Plus Pygeum by DC: Common Questions

Does Maca Plus Pygeum by DC interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maca Plus Pygeum. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maca Plus Pygeum contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is pygeum actually effective for prostate problems?
Yes—pygeum extract is rated likely effective for benign prostatic hyperplasia, the enlarged prostate common in older men. The research backs this use.
What about maca—does it work for sexual health?
Maca has been studied for sexual desire and other uses, but the evidence right now is insufficient. We can't say it works or doesn't; we just don't have enough solid research yet.
Can I take this if I'm pregnant or breastfeeding?
No. Maca should be avoided during pregnancy and breastfeeding due to lack of safety data. Pygeum, designed for men's prostate health, also has no established safe use in pregnancy and should be avoided while breastfeeding. Talk to your doctor or pharmacist about your situation.
What side effects might I see?
Maca may cause stomach pain, especially if it's uncooked. Pygeum has been linked to nausea and belly pain in studies, though these happened at rates similar to placebo. Most people tolerate both short term.
Is this safe to take long term?
Maca hasn't been studied long term as a supplement, and pygeum's long-term safety data are limited. Both are generally well tolerated in the short run, but don't rely on either as a permanent solution without checking in with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maca Plus Pygeum is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maca Plus Pygeum label
Sources

Sources & How We Checked

Maca Plus Pygeum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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